Protein Alignment Pax6 and gsb-n

DIOPT Version :10

• Sequence 1: NP_038655.1
• Gene: Pax6 / 18508
• MGIID: 97490
• Length: 436
• Species: Mus musculus
• Sequence 2: NP_523862.1
• Gene: gsb-n / 38004
• FlyBaseID: FBgn0001147
• Length: 449
• Species: Drosophila melanogaster
• Alignment Length: 422
• Identity: 155/422 - (36%)
• Similarity: 198/422 - (46%)
• Gaps: 111/422 - (26%)

Mouse     8 VNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNENVSNGCVSKILG 72
            ||||||||:||||||:..|.||||:|.||.|||.|||.|:              ||:|||||||.
  Fly    24 VNQLGGVFINGRPLPNHIRLKIVEMAASGVRPCVISRQLR--------------VSHGCVSKILN 74

Mouse    73 RYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSVSSI 137
            ||.|||||||..||||||:|.:||:.::|.:.::|.||||:||||::|:.||..   :.||.|||
  Fly    75 RYQETGSIRPGVIGGSKPKVTSPEIETRIDELRKENPSIFSWEIREKLIKEGFA---DPPSTSSI 136

Mouse   138 NRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQPTQDGCQQQEGGGENTN 202
            :|:||.    ..:...||..|  ..:||..|
  Fly   137 SRLLRG----SDRGSEDGRKD--YTINGILG---------------------------------- 161

Mouse   203 SISSNGEDSD----EAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDL 263
                 |.|||    |::..:.||||.:|:||:||.||:||||:.|.||.||||:.||.||....|
  Fly   162 -----GRDSDISDTESEPGIPLKRKQRRSRTTFTAEQLEALERAFSRTQYPDVYTREELAQTTAL 221

Mouse   264 PEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPISSSFSTSVYQPIPQPTTPV--SSFTSG 326
            .|||||||||||||:.|:.....|......|       |.|.:..|...:...|.|:  .....|
  Fly   222 TEARIQVWFSNRRARLRKHSGGSNSGLSPMN-------SGSSNVGVGVGLSGATAPLGYGPLGVG 279

Mouse   327 SMLGRTDTALTNTYSALPPMPSFTMANNLPMQPPVPSQTSSYSCM------LPTSPSVNGRSYDT 385
            ||.|         ||                  |.|..|::.:.|      ...:||.:..:...
  Fly   280 SMAG---------YS------------------PAPGTTATGAGMNDGVHHAAHAPSSHHSAATA 317

Mouse   386 YTPPHMQTHMNSQPMGTSGTT---STGLISPG 414
            ....|..|.|....:..|...   ..|...||
  Fly   318 AAAAHHHTQMGGYDLVQSAAQHGFPGGFAQPG 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pax6	NP_038655.1	PAX	4..142	CDD:128645	75/133 (56%)
		Homeodomain	226..281	CDD:459649	36/54 (67%)
gsb-n	NP_523862.1	HTH_CRP	20..141	CDD:481199	75/133 (56%)
		Homeodomain	183..239	CDD:459649	36/55 (65%)