Protein Alignment Pax4 and al

DIOPT Version :10

• Sequence 1: NP_035168.1
• Gene: Pax4 / 18506
• MGIID: 97488
• Length: 349
• Species: Mus musculus
• Sequence 2: NP_722629.1
• Gene: al / 33208
• FlyBaseID: FBgn0000061
• Length: 408
• Species: Drosophila melanogaster
• Alignment Length: 222
• Identity: 67/222 - (30%)
• Similarity: 91/222 - (40%)
• Gaps: 34/222 - (15%)

Mouse   156 HSNCGAPRGPHPGTSHRNRTIFSPGQAEALEKEFQRGQYPDSVARGKLAAATSLPEDTVRVWFSN 220
            :|:|.|..........|.||.|:..|.|.|||.|.|..|||...|.:||....|.|..::|||.|
  Fly    71 NSDCEADEYAPKRKQRRYRTTFTSFQLEELEKAFSRTHYPDVFTREELAMKIGLTEARIQVWFQN 135

Mouse   221 RRAKWRRQEKL-----KWEAQLPGASQDL------TVPKNSPGIISAQ-------QSPGSVPSAA 267
            ||||||:|||:     .:...|||.:..:      .:|.|....:..|       |...::.:..
  Fly   136 RRAKWRKQEKVGPQSHPYNPYLPGGAATMQTVVGAALPPNPFTHLGFQLRKPFDAQHAANLAAFR 200

Mouse   268 LPVLE--PLSPS--FCQ--------LCCGTAPGRCSSDTSSQAYLQPYWDCQSLLPVASSSYVEF 320
            .|.|.  |:.||  |.|        |..|.| |..|..:|.|:.|..........|:.....:..
  Fly   201 YPHLSAAPMIPSGYFNQFQRAPPHMLPHGMA-GMYSPSSSFQSLLANMTAVPRGTPLGKPPALLV 264

Mouse   321 AWPCLTTHPVHHLIGGPGQVP-STHCS 346
            ..|.|  |..:|::..|...| |.|.|
  Fly   265 GSPDL--HSPNHMLASPPTSPASGHAS 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pax4	NP_035168.1	PAX	5..129	CDD:128645
		PAI subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381	8..64
		RED subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381	83..131
		Homeodomain	172..227	CDD:459649	28/54 (52%)
		Transcription repression	278..349		20/78 (26%)
al	NP_722629.1	Homeodomain	86..142	CDD:459649	28/55 (51%)
		OAR	374..391	CDD:461067