DRSC/TRiP Functional Genomics Resources

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Protein Alignment Pax3 and Gsc

DIOPT Version :10

Sequence 1:NP_001152992.1 Gene:Pax3 / 18505 MGIID:97487 Length:484 Species:Mus musculus
Sequence 2:NP_001137762.2 Gene:Gsc / 33240 FlyBaseID:FBgn0010323 Length:473 Species:Drosophila melanogaster


Alignment Length:148 Identity:58/148 - (39%)
Similarity:73/148 - (49%) Gaps:24/148 - (16%)


- Green bases have known domain annotations that are detailed below.


Mouse   214 PLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQA 278
            |.||| ||.||.||.||||:||..|::|||||:..||:||.:..|.|.||:|||.||||:||||.
  Fly   336 PPKRK-RRHRTIFTEEQLEQLEATFDKTHYPDVVLREQLALKVDLKEERVEVWFKNRRAKWRKQK 399

Mouse   279 GANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPTS----IPQAVSDPSSTVHRP--QPLPPS 337
            ...|              ..:..|...|...|:...|:    ...:..:.|.||..|  ......
  Fly   400 REEQ--------------ERLRKLQEEQCGSTTNGTTNSSSGTTSSTGNGSLTVKCPGSDHYSAQ 450

Mouse   338 TVHQSTIP---SNADSSS 352
            .||..:.|   |:||.||
  Fly   451 LVHIKSDPNGYSDADESS 468

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Pax3NP_001152992.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..21
PAX 34..159 CDD:128645
PAI subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381 37..93
RED subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381 113..161
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 165..228 9/13 (69%)
Homeodomain 220..276 CDD:459649 34/55 (62%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 309..351 12/50 (24%)
Pax7 347..391 CDD:403540 4/6 (67%)
GscNP_001137762.2 Homeodomain 341..397 CDD:459649 34/55 (62%)
Blue background indicates that the domain is not in the aligned region.

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