DRSC/TRiP Functional Genomics Resources

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Protein Alignment Pax3 and oc

DIOPT Version :10

Sequence 1:NP_001152992.1 Gene:Pax3 / 18505 MGIID:97487 Length:484 Species:Mus musculus
Sequence 2:NP_001356934.1 Gene:oc / 31802 FlyBaseID:FBgn0004102 Length:664 Species:Drosophila melanogaster


Alignment Length:301 Identity:79/301 - (26%)
Similarity:114/301 - (37%) Gaps:80/301 - (26%)


- Green bases have known domain annotations that are detailed below.


Mouse   217 RKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWR----KQ 277
            |||||.|||||..||:.||..|.:|.||||:.|||:|.:..|.|:||||||.||||:.|    :|
  Fly    65 RKQRRERTTFTRAQLDVLEALFGKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQLQQQ 129

Mouse   278 AGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQS 342
            ..:|.|.:..:...||...:.       ..|..:.:..|.....|..::|             ||
  Fly   130 QQSNSLSSSKNASGGGSGNSC-------SSSSANSRSNSNNNGSSSNNNT-------------QS 174

Mouse   343 TIPSNADSSSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNPTIGNGLS-----PQVMGLLTNH--- 399
            :..:|::.|      |.:.|.|..:......||.:|..|.:.....|     .....:.|:|   
  Fly   175 SGGNNSNKS------SQKQGNSQSSQQGGGSSGGNNSNNNSAAAAASAAAAVAAAQSIKTHHSSF 233

Mouse   400 ---------GG-----------------VPHQPQTDYALSPLTGGLEPTTTVSASCSQRLEHMKN 438
                     ||                 .|:...:........||.......:|:.:....|..:
  Fly   234 LSAAAAAASGGTNQSANNNSNNNNQGNSTPNSSSSGGGGGSQAGGHLSAAAAAAALNVTAAHQNS 298

Mouse   439 VDSLPTSQPYCPPTYSTAGYSMDPVT-----GYQYGQYGQS 474
            ...|||     |.|      |:.||:     .:..|.||.|
  Fly   299 SPLLPT-----PAT------SVSPVSIVCKKEHLSGGYGSS 328

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Pax3NP_001152992.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..21
PAX 34..159 CDD:128645
PAI subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381 37..93
RED subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381 113..161
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 165..228 9/10 (90%)
Homeodomain 220..276 CDD:459649 34/59 (58%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 309..351 6/41 (15%)
Pax7 347..391 CDD:403540 10/48 (21%)
ocNP_001356934.1 Homeodomain 68..123 CDD:459649 33/54 (61%)
Blue background indicates that the domain is not in the aligned region.

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