DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Pax1 and al

DIOPT Version :9

Sequence 1:XP_006498974.1 Gene:Pax1 / 18503 MGIID:97485 Length:534 Species:Mus musculus
Sequence 2:NP_722629.1 Gene:al / 33208 FlyBaseID:FBgn0000061 Length:408 Species:Drosophila melanogaster


Alignment Length:424 Identity:91/424 - (21%)
Similarity:133/424 - (31%) Gaps:137/424 - (32%)


- Green bases have known domain annotations that are detailed below.


Mouse   114 PGAGGALGSGSLRVSSRRGPRLARALPLCLSGGGGARALP------DCAGP--SPRRSGAR---- 166
            ||:..|....:|.||.    .::...|...||..|....|      ||...  :|:|...|    
  Fly    31 PGSSAASAGAALTVSM----SVSGGAPSGASGASGGTNSPVSDGNSDCEADEYAPKRKQRRYRTT 91

Mouse   167 ----QLAGPRAMEQTYGEVNQLGGVFVNGRPLPNAIRLRIVELA-QLGIRPCDIS---RQLRVSH 223
                ||   ..:|:.:...: ...||..            .||| ::|:....|.   :..|...
  Fly    92 FTSFQL---EELEKAFSRTH-YPDVFTR------------EELAMKIGLTEARIQVWFQNRRAKW 140

Mouse   224 GCVSKILARYNETGSILPG-------AIGGSKPRVTTPNVVKHIRDYKQGDPGIFAWEIRDRLLA 281
            ....|:..:.:.....|||       .:|.:.|    ||...|:           .:::|....|
  Fly   141 RKQEKVGPQSHPYNPYLPGGAATMQTVVGAALP----PNPFTHL-----------GFQLRKPFDA 190

Mouse   282 DGVCD--KYNVPSVSSISRILRNKIGSLAQPGPYEASKQPPPQPALPYNHIYQYPYPSPVS---- 340
            ....:  .:..|.:|:...|          |..|....|..|...||:.....|   ||.|    
  Fly   191 QHAANLAAFRYPHLSAAPMI----------PSGYFNQFQRAPPHMLPHGMAGMY---SPSSSFQS 242

Mouse   341 --------PTGTKMGTHPG-VPGSAGHVSIPRSWPSAHSVSNILGIRTFMEQTGALAGSE--GAA 394
                    |.||.:|..|. :.||          |..||.:::|........:|..:..:  ..|
  Fly   243 LLANMTAVPRGTPLGKPPALLVGS----------PDLHSPNHMLASPPTSPASGHASQHQQHPTA 297

Mouse   395 YSPKMEDWAGVNRAAFPTSPAVNGLEKPALE----ADIKYTQSASSLSAVGGFLPACAYPASNQH 455
            :.|..:        |.|..|.  |::...|.    ..|..||.|||||.                
  Fly   298 HPPPPQ--------APPQMPV--GVQPAQLSPQHLVGIALTQQASSLSP---------------- 336

Mouse   456 GVYSAPAAGYLSPGP----PWPPAQAPPLTPHGA 485
             ..::|.|..||..|    |.|..||||..|..|
  Fly   337 -TQTSPVALTLSHSPQRQLPPPSHQAPPPPPRAA 369

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Pax1XP_006498974.1 PAX 177..304 CDD:238076 22/139 (16%)
alNP_722629.1 Homeobox 89..141 CDD:278475 11/67 (16%)
OAR 374..391 CDD:281777
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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