DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment F15H10.7 and CG32985

DIOPT Version :9

Sequence 1:	NP_505674.1	Gene:	F15H10.7 / 184555	WormBaseID:	WBGene00008874	Length:	666	Species:	Caenorhabditis elegans
Sequence 2:	NP_788013.2	Gene:	CG32985 / 326244	FlyBaseID:	FBgn0052985	Length:	644	Species:	Drosophila melanogaster

Alignment Length:	703	Identity:	172/703 - (24%)
Similarity:	297/703 - (42%)	Gaps:	120/703 - (17%)

- Green bases have known domain annotations that are detailed below.

Worm     6 IFYNYSHYITYYSKVALIFVICFGVYYGLFRTETDFSTHPHFLYLQKLRDSQ--------SKSEC 62
            |.|::...|..:..|.||.:...    ...|.:.:||.          ||||        ...:|
  Fly     5 ISYSFKRLIVSFLAVTLICLWSM----NSSRVDENFSA----------RDSQEVEKLFYVESGKC 55

Worm    63 VIPDADPWDPSILSYYSKPSPLVCST----MQVQAVKSFNNGILTFEPQVI--------KNARCY 115
            .:...:|::...|......:.:.|:.    :.|...|..|..:|....:|:        .:..|:
  Fly    56 KMRYVNPFNAEFLKINHPKAFIPCTNESDLISVHYDKILNQYVLHTNEEVLHELSESKTNDFACF 120

Worm   116 KTGIRHDENVTDLDVIYEKPVPLNLTHTSSIKISDEVFQITCESDN---LLKSEIFKYHYTQIVP 177
            ...|.:.::....|   .|.|...::....:.:..|...:.|.:.:   :|:.:.|.  :.|...
  Fly   121 YQKIIYGQSAEHYD---GKGVKTKISQNHLVPLDVEGMLVECRTADEMRVLQRDAFV--FVQYKD 180

Worm   178 KSSNIKNKVIEQSTSDFPSVIMIGLDSMSRGNFVRQMQKTYKYMKEAGFIDMEGHMKIHDNTYGN 242
            ...|:  |.::::     ||||.|:|::||.|..|.|...::::|..|:.:|.|:.|:.||::.|
  Fly   181 PPQNV--KPVKKA-----SVIMYGIDTVSRTNLRRMMPMVFEFLKSPGWYEMMGYNKVADNSFPN 238

Worm   243 LLAILTGKRGVGVKEFSTE------INESWHIAFDEFDFIWKTFSDNGYATLFAEDRPDIGTFTY 301
            :.|:|||        ||.|      .|.......|:..||||.|..:||.|.:|||.....||.|
  Fly   239 IFAMLTG--------FSPESAETQICNTDVDGCLDKIPFIWKDFKKDGYLTAYAEDEEHSNTFNY 295

Worm   302 KNMLEGFLKQPTDHYIRPFWISAFWS--------------LISRRSVASCYDSTPQHKIQLKYLE 352
            ..  .||..:|||:|.||| ::|..:              .:.|| :||.|        ...|..
  Fly   296 AK--PGFAVKPTDYYFRPF-LTALENETFIQYCPGCVMKYCLGRR-LASSY--------IFDYCR 348

Worm   353 EFLEKYDKKRK-FAFWWSQDMSHGFLNLIG----KVDDDFEKFFKNNEKRMEDSIIIVFSDHGHR 412
            :|::::...|. :..:|:...||..|.::.    |:.:|...|.|:..  .|.:|:|.|||||.|
  Fly   349 QFMQRFVADRPIWGMFWTNHYSHDDLFMLSAMQHKILEDLLSFEKDGV--FEHTIMIFFSDHGAR 411

Worm   413 YDKIRETVIGRIESRMPFHSIRIPDGIKKKYPQIVENLMVNSKLMTTQFDVNDSLRKIAT--GKV 475
            :..:..|....:|.|:|...|.:|...:||||:.||.|..|...:::.||:.::|:.|..  |.|
  Fly   412 FGPLMYTKEAFLEERLPMMFIYLPPWFRKKYPRYVEALAQNQNRLSSNFDLYNTLKHIINIEGLV 476

Worm   476 GE-KWTQTDRKRSYSYFDPFPKRIGCYEAGIPSDFCPCFSEIEIPKSEAKEAAVELMRIVNDLLE 539
            .: ||:. |..:..|.|.|.|:...|.||.||..:|.|.:..||.:.:.      ..|:.|.:::
  Fly   477 EDTKWSY-DCPQCQSLFYPLPESRSCSEAAIPEAYCTCHNYEEIKEDQG------TWRLANLVVD 534

Worm   540 NTEKTEEYEPDSKELTEYMCTPMEIQNVEFSSVRLPMLSVLKDVKSEDTPLQSFSLQYHVVVRAK 604
            ...|...|..     .:.:|:.:.::.:..:.||:         ..:|..|.:....||...:..
  Fly   535 RMNKYLHYHN-----LQNLCSNLTLRVINSTEVRM---------DDKDVDLANGMRHYHTKFQVH 585

Worm   605 APSNALLESTLEHNLKTNTWSSLGEVERNNKYGNTSFCVNDRILKKICHCISR 657
            ........:.|..........::..:.|.|.||..|.|||::|.|..|.|:|:
  Fly   586 QNLAEFFATVLYDKQTEELQMNVELISRTNMYGTDSECVNNKIQKLYCVCLSK 638

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
F15H10.7	NP_505674.1	DUF229	79..568	CDD:281053	136/531 (26%)
F15H10.7	NP_505674.1	ALP_like	195..472	CDD:293745	95/301 (32%)
CG32985	NP_788013.2	DUF229	72..554	CDD:308570	136/527 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000