Protein Alignment DUSP3 and MKP-4

DIOPT Version :10

• Sequence 1: NP_004081.1
• Gene: DUSP3 / 1845
• HGNCID: 3069
• Length: 185
• Species: Homo sapiens
• Sequence 2: NP_608332.2
• Gene: MKP-4 / 32963
• FlyBaseID: FBgn0031044
• Length: 387
• Species: Drosophila melanogaster
• Alignment Length: 177
• Identity: 56/177 - (31%)
• Similarity: 86/177 - (48%)
• Gaps: 29/177 - (16%)

Human    31 NEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQE 95
            :||...:::||.:.|..:..|:...|||:|.........|: ..|:|     :|...|:..|...
  Fly    40 DEVDTGLFLGNLTAATHMETLRSFKITHILTLDSVPLPQHI-LEASF-----LTTKYIQIADMPR 98

Human    96 FNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNRE- 159
            .::..:.|...|||..||||: |.|||||..|.|||.:.||||:|.|..:|...|..:|:..|.
  Fly    99 EDILQHLEGCVDFISSALAQQ-GNVLVHCYFGVSRSSSTVIAYMMKRHNLDFLPAYELVKAKRRF 162

Human   160 IGPNDGFLAQL-------CQLND----------RLA----KEGKLKP 185
            :.||.||::||       |:::.          |||    ::.|:.|
  Fly   163 VQPNAGFVSQLKLFRRMGCKIDPNCQRYKIHRLRLAGEQMRKAKILP 209

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DUSP3	NP_004081.1	DUSP3	10..177	CDD:350427	51/163 (31%)
MKP-4	NP_608332.2	DSP	39..175	CDD:350348	50/141 (35%)