Protein Alignment P2ry2 and AstC-R1

DIOPT Version :9

• Sequence 1: NP_001289275.1
• Gene: P2ry2 / 18442
• MGIID: 105107
• Length: 373
• Species: Mus musculus
• Sequence 2: NP_649040.2
• Gene: AstC-R1 / 40020
• FlyBaseID: FBgn0036790
• Length: 483
• Species: Drosophila melanogaster
• Alignment Length: 384
• Identity: 100/384 - (26%)
• Similarity: 169/384 - (44%)
• Gaps: 66/384 - (17%)

Mouse    27 FNEDFKYVLLPVSYGVVCVLGLCLNVVALYIFLCRLKTWNASTTYMFHLAVSDSLYAASLPLLVY 91
            |.:.|..||    ||.||::||..|.:.:|:.|...|....:..|:.:|||:|..:...:|.|:
  Fly    75 FADLFTVVL----YGFVCIIGLFGNTLVIYVVLRFSKMQTVTNIYILNLAVADECFLIGIPFLL- 134

Mouse    92 YYARGDHWPFSTVLCKLVRFLFYTNL--YCSILFLTCISVHRCLGVLRPLHSLRWGRARYARRVA 154
            |..|...|.|...:||  .::..|::  :.|.:||..:|..|.:.|..|:.|.|:.....|:.|:
  Fly   135 YTMRICSWRFGEFMCK--AYMVSTSITSFTSSIFLLIMSADRYIAVCHPISSPRYRTLHIAKVVS 197

Mouse   155 AVVWVLVLACQAPVLYFVTTSVR--GTRITCH----DTSARELFSHFVAYSSVMLGLLFAVPFSV 213
            |:.|........||:.:.:|..:  |...:|:    |...:...:.|:.| :..||  ||.|...
  Fly   198 AIAWSTSAVLMLPVILYASTVEQEDGINYSCNIMWPDAYKKHSGTTFILY-TFFLG--FATPLCF 259

Mouse   214 ILVCYVLMARRL--LKPAYGT-TGGLPRAKRKSVRTIALVLAVFALCFLPFHLTRT--LYYSFRS 273
            ||..|.|:.|:|  :.|..|| :....||.||..|.:..|::|:.||:||..:::.  ::.:...
  Fly   260 ILSFYYLVIRKLRSVGPKPGTKSKEKRRAHRKVTRLVLTVISVYILCWLPHWISQVALIHSNPAQ 324

Mouse   274 LDLSCHTLNAINMAYKITRPLASANSCLDPVLY-FLAGQRLVRFAR----------DAKPPTEP- 326
            .|||...:    :.:.:...|..:||.::|:|| ||:......|.:          :|:...||
  Fly   325 RDLSRLEI----LIFLLLGALVYSNSAVNPILYAFLSENFRKSFFKAFTCMNKQDINAQLQLEPS 385

Mouse   327 -----------------TPSPQARRKLGLHRPNRTVRKDLSVSSDDSRRTESTPAGSET 368
                             |.:||....|.|:..|          ::.|..|.||....:|
  Fly   386 VFTKQGSKKRGGSKRLLTSNPQIPPLLPLNAGN----------NNSSTTTSSTTTAEKT 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
P2ry2	NP_001289275.1	7tm_1	51..306	CDD:278431	71/267 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	318..373		14/79 (18%)
AstC-R1	NP_649040.2	7tm_4	88..368	CDD:304433	79/289 (27%)
		7tm_1	94..353	CDD:278431	71/268 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X22
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000