Protein Alignment DUSP2 and Mkp3

DIOPT Version :9

• Sequence 1: XP_016859035.1
• Gene: DUSP2 / 1844
• HGNCID: 3068
• Length: 342
• Species: Homo sapiens
• Sequence 2: NP_001262031.1
• Gene: Mkp3 / 40081
• FlyBaseID: FBgn0036844
• Length: 497
• Species: Drosophila melanogaster
• Alignment Length: 379
• Identity: 110/379 - (29%)
• Similarity: 166/379 - (43%)
• Gaps: 106/379 - (27%)

Human    23 EAERTLLLDCRPFLAFCRRHVRAA--RPVPWNALLRRRARGPPAAVLACLLPDRALRTRLVRG-- 83
            :::..:|||||....:...|:|.|  ..:| :.:|||.|.|  ...||..:....|:.|:..|
  Fly    22 DSKDLILLDCRGSHEYSESHIRGAVNLCIP-SIVLRRLAVG--KIDLASTIKSPELKQRIQSGYK 83

Human    84 -----------------ELARAVVLDEGSASVAELRPDSPAHVLLAALLHETRAGPTAVYFLRGE 131
                             |:|.|     ||.:||   .||     :.::||.           |.:
  Fly    84 LCWFILYNGEGVPGQNQEIAGA-----GSLAVA---MDS-----IISILHR-----------RLK 124

Human   132 QAGRPWPAPPDSSPAFPADRALPLLAGGFDGFQGCCPDLCSE-----------------APAPAL 179
            |.|                ..:..|..||:.|:...|:.|.:                 .....|
  Fly   125 QDG----------------CRVVALQDGFNNFRQAFPEWCEDDNQTHSKEIESSRNVQTDQLMGL 173

Human   180 PPTGDKTSRSDSRAPV---------------------YDQGGPVEILP-YLFLGSCSHSSDLQGL 222
            ......|::|||....                     |:: .||||:| .||||:.:||.|.:.|
  Fly   174 RSLRISTTQSDSACSSSAESSDCESSSHHHHHHSHHNYNE-APVEIIPGLLFLGNATHSCDSEAL 237

Human   223 QACGITAVLNVSASCPNHFE--GLFRYKSIPVEDNQMVEISAWFQEAIGFIDWVKNSGGRVLVHC 285
            :...|..||||:...||.|:  |..:|..||:.|:...:::..|.:||.||:..:::...|||||
  Fly   238 KKYNIKYVLNVTPDLPNKFKESGDIKYLQIPITDHYSQDLAIHFPDAIQFIEEARSASSVVLVHC 302

Human   286 QAGISRSATICLAYLMQSRRVRLDEAFDFVKQRRGVISPNFSFMGQLLQFETQV 339
            .||:|||.|:.|||||.:|.:.|::||..|:.|:..:||||.||.|||.||:|:
  Fly   303 LAGVSRSVTVTLAYLMHTRGLSLNDAFAMVRDRKPDVSPNFHFMQQLLSFESQL 356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DUSP2	XP_016859035.1	None
Mkp3	NP_001262031.1	DSP_MapKP	8..148	CDD:238723	38/168 (23%)
		DSPc	215..353	CDD:238073	62/137 (45%)
		CDC14	<242..359	CDD:225297	52/115 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X468
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910