DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment F07C3.3 and CG32985

DIOPT Version :9

Sequence 1:	NP_505391.4	Gene:	F07C3.3 / 184124	WormBaseID:	WBGene00017194	Length:	746	Species:	Caenorhabditis elegans
Sequence 2:	NP_788013.2	Gene:	CG32985 / 326244	FlyBaseID:	FBgn0052985	Length:	644	Species:	Drosophila melanogaster

Alignment Length:	763	Identity:	162/763 - (21%)
Similarity:	269/763 - (35%)	Gaps:	249/763 - (32%)

- Green bases have known domain annotations that are detailed below.

Worm    66 LWNINVFGDDDNIKT----EIER--------------DP-----LLTHHPFDNTCKFPLPNSYAE 107
            ||::|....|:|...    |:|:              :|     |..:||     |..:|.:...
  Fly    24 LWSMNSSRVDENFSARDSQEVEKLFYVESGKCKMRYVNPFNAEFLKINHP-----KAFIPCTNES 83

Worm   108 DIIPFHLSERMRQ-----------------------------------------LKCEVKQKDYA 131
            |:|..|..:.:.|                                         :|.::.|....
  Fly    84 DLISVHYDKILNQYVLHTNEEVLHELSESKTNDFACFYQKIIYGQSAEHYDGKGVKTKISQNHLV 148

Worm   132 TMDSEGYIYVHPHFVDWPRLERDVQCKVDIIEGGLRKPERNMTKNSMFIKKTLEIPSNERLFVNA 196
            .:|.||.:               |:|:.                            ::|...:..
  Fly   149 PLDVEGML---------------VECRT----------------------------ADEMRVLQR 170

Worm   197 DAFVINCYNHSKKAVKPEVPIWKKPFPGMKDKNLPEDEILRVKDLYSYGDYGNKIREQVSKAVDR 261
            ||||...|....:.|||                                         |.||
  Fly   171 DAFVFVQYKDPPQNVKP-----------------------------------------VKKA--- 191

Worm   262 YSIDILGFDSTARTMFMRHMPRTVEVMAKLDYHYLYGYTKVADNSMVNLAPILVGDMEEALKKPK 326
             |:.:.|.|:.:||...|.||...|.:....::.:.||.||||||..|:..:|.|...|:.:...
  Fly   192 -SVIMYGIDTVSRTNLRRMMPMVFEFLKSPGWYEMMGYNKVADNSFPNIFAMLTGFSPESAETQI 255

Worm   327 YDKSGDFNINWLLPTEDKMDPTKLNFLWKIMKEKYGCESLFNEDISTKGLGLFNYPPTEFQPGFT 391
            .:...|..::            |:.|:||..| |.|..:.:.||  .:....|||.    :|||.
  Fly   256 CNTDVDGCLD------------KIPFIWKDFK-KDGYLTAYAED--EEHSNTFNYA----KPGFA 301

Worm   392 ENPADHYYRAYYLAVYENWKYEACRD-------GEQLQNEFV-NIWRRFAHRY---RNICHFGFT 445
            ..|.|:|:|.:..|:......:.|..       |.:|.:.:: :..|:|..|:   |.|  :|..
  Fly   302 VKPTDYYFRPFLTALENETFIQYCPGCVMKYCLGRRLASSYIFDYCRQFMQRFVADRPI--WGMF 364

Worm   446 FVTTLTHEAGLVLEILDEKLAAHLSQMHLNGDLDNTLSIIMGDHGNRIGAIKSRYTGRIEERMPL 510
            :....:|:...:|..:..|:...|.....:|..::|:.|...|||.|.|.:.......:|||:|:
  Fly   365 WTNHYSHDDLFMLSAMQHKILEDLLSFEKDGVFEHTIMIFFSDHGARFGPLMYTKEAFLEERLPM 429

Worm   511 MAMRFPTGFAETYPVEYKNFLDNKHKLTSNFDVHKTLHDIVHMR--LGDNKAKSDEGRGISLFDA 573
            |.:..|..|.:.||...:....|:::|:||||::.||..|:::.  :.|.|...|..:..|||..
  Fly   430 MFIYLPPWFRKKYPRYVEALAQNQNRLSSNFDLYNTLKHIINIEGLVEDTKWSYDCPQCQSLFYP 494

Worm   574 IPNTRTCADVIVPENFCMCMIDVSSIANPLPNFNKKKPTDQ--------KMDQFNTLKSWLKTEN 630
            :|.:|:|::..:||.:|.|           .|:.:.| .||        .:|:.|   .:|...|
  Fly   495 LPESRSCSEAAIPEAYCTC-----------HNYEEIK-EDQGTWRLANLVVDRMN---KYLHYHN 544

Worm   631 LDDCVDVSSLETGQTFQEMAINPLSRFGLRTKNNASMLELMKERNKKNPELNY-INF-------E 687
            |.                   |..|...||..|:..:....|:.:..|...:| ..|       |
  Fly   545 LQ-------------------NLCSNLTLRVINSTEVRMDDKDVDLANGMRHYHTKFQVHQNLAE 590

Worm   688 FSVSGTY-KNGEPLSMLV----RTELFVEKSTSQLIFEPMIQEMPASC 730
            |..:..| |..|.|.|.|    ||.::   .|........||::...|
  Fly   591 FFATVLYDKQTEELQMNVELISRTNMY---GTDSECVNNKIQKLYCVC 635

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
F07C3.3	NP_505391.4	DUF229	75..623	CDD:308570	133/632 (21%)
CG32985	NP_788013.2	DUF229	72..554	CDD:308570	132/629 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165296
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.930