DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment chil-11 and Cht10

DIOPT Version :9

Sequence 1:	NP_500856.2	Gene:	chil-11 / 183470	WormBaseID:	WBGene00016665	Length:	389	Species:	Caenorhabditis elegans
Sequence 2:	NP_001036422.1	Gene:	Cht10 / 3355116	FlyBaseID:	FBgn0250907	Length:	2286	Species:	Drosophila melanogaster

Alignment Length:	368	Identity:	88/368 - (23%)
Similarity:	157/368 - (42%)	Gaps:	68/368 - (18%)

- Green bases have known domain annotations that are detailed below.

Worm    35 THAVFG-------SLRVQLNGTF-EIGNAFSKRKFKNWQRAVKNSSSNVKSMISIGRW-DSV-TQ 89
            ||.::|       :|.:|.:.:: ::.|.|       ::|.|.......|..::||.| ||. .:
  Fly  1439 THIIYGFAVLSRDNLTIQPHDSWADLDNKF-------YERIVAYRKKGAKVTVAIGGWNDSAGDK 1496

Worm    90 LSSVLLNVKSRRMFIESIVDFLKEHQLDGIDLFWRWVPLAVQSE-----------FCLFLEEVKI 143
            .|.::.|.::|..||.:::||::|:..||:||.|.: |:..|.:           |...:.|:..
  Fly  1497 YSRLVRNPEARSRFIRNVLDFIEEYNFDGLDLDWEY-PVCWQVDCKKGTAEEKIGFSALVRELFY 1560

Worm   144 EFLNQEKQYILSITAPPVGIENYEDGYDIEEIIERVDFVNVYSMNYAAPWSNQWGTPTGPSAPLY 208
            .|  |.:..|||....| ..:..:.||::.|:.....:::|.:.:|    ..||...||..||:|
  Fly  1561 AF--QPRGLILSAAVSP-NKKVIDAGYEVAELSHYFSWISVMAYDY----HGQWDKKTGHVAPMY 1618

Worm   209 GGLDARRKFSVDYTMKYYIRYTRKPEKFNLIIPFYVRHWRNVENAIKPGIEVFRNVTLQNNGAIG 273
            ...:....|:.:::|.|:|.......|..:.||.|.:.:...|.. |..:    |......|..|
  Fly  1619 SHPEGTANFNANFSMNYWISMGADRRKLVMGIPLYGQSFSLAETT-KHQL----NAPTYGGGEAG 1678

Worm   274 EVYMSRWTAESDG--------IELSNPSWD---DTTKTLYIWKPETKTFITFETEKSIEAKANYV 327
            |...:|      |        :::.:..|:   ||...:..:......:::|:....|..|:.|:
  Fly  1679 EATRAR------GFLAYYEICLKIRHHRWNVVRDTKGRIGPFAYHGDQWVSFDDVPMIRHKSEYI 1737

Worm   328 KSMNLGGVWIWLMENDDQDN----------SMIEAVSGQFGNP 360
            |:|.|||..||.::.||..|          ..|..|...||.|
  Fly  1738 KAMGLGGAMIWALDLDDFKNVCECESYPLLKAINRVLRGFGGP 1780

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
chil-11	NP_500856.2	Glyco_18	13..343	CDD:214753	80/339 (24%)
Cht10	NP_001036422.1	Glyco_18	220..565	CDD:214753
		GH18_chitolectin_chitotriosidase	221..586	CDD:119351
		ChtBD2	697..737	CDD:214696
		CBM_14	801..848	CDD:279884
		CBM_14	875..918	CDD:279884
		Glyco_18	966..1310	CDD:214753
		GH18_chitolectin_chitotriosidase	967..1331	CDD:119351
		Glyco_18	1410..1753	CDD:214753	80/339 (24%)
		GH18_chitolectin_chitotriosidase	1411..1774	CDD:119351	84/360 (23%)
		ChtBD2	1834..1871	CDD:214696
		Glyco_18	1909..2253	CDD:214753
		GH18_chitolectin_chitotriosidase	1910..2274	CDD:119351
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160164211
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740