DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment chil-7 and Cht10

DIOPT Version :9

Sequence 1:	NP_496131.2	Gene:	chil-7 / 182437	WormBaseID:	WBGene00007472	Length:	482	Species:	Caenorhabditis elegans
Sequence 2:	NP_001036422.1	Gene:	Cht10 / 3355116	FlyBaseID:	FBgn0250907	Length:	2286	Species:	Drosophila melanogaster

Alignment Length:	397	Identity:	87/397 - (21%)
Similarity:	156/397 - (39%)	Gaps:	97/397 - (24%)

- Green bases have known domain annotations that are detailed below.

Worm   123 KCNKRIVGYYTDWEPRKISAKQLQKLTHLIFTNVPMNSSGHVFF-------ENLAQRR--RFLEI 178
            |..|:::.|.::|      |.......|.:...:..|....:.:       ::|..|.  .::::
  Fly   216 KMTKKVLCYMSNW------AFYRSGEAHFVPEQIDPNLCSAIIYSFASLDPDHLTIREFDSWVDL 274

Worm   179 N----RKAQLMNVKVMFSIGG--HKNAEHYSTVVADSTKRSVFIDSIVSFIKSNNASGVDLFWEW 237
            :    |:...:.|.|:.::||  ..:...||.:|:|:.||.|||.|:.||:..:..||:.|.|.:
  Fly   275 DNQYYRRVTSLGVPVLIALGGWTDSSGSKYSRLVSDNLKRRVFISSVSSFLLRHGFSGLHLDWNY 339

Worm   238 PN----------ISEMNDFITTIKELRKKLAALTKAQPKGTRYLLSIIVPSSPSDLEYYLRMDGL 292
            |.          :::..:....::|||      |:.|....::.|.:.:......::.......|
  Fly   340 PKCWQSDCSRGPVTDRPNLTKLLRELR------TEFQSVDPKFQLGVAISGYKEIIKEAYDFPAL 398

Worm   293 LHYVDFLNVLTYGYYAPWSGVNGKFVGPNAPLYGGNRE-----NVDETMQYLICKTRTPSKLNMA 352
            ...||::.|:||.|:..|....|..    :||||.:.:     |.:.|||.|:.......||.::
  Fly   399 SDIVDYMTVMTYDYHGAWEQKTGHV----SPLYGLSSDTYPQYNTNYTMQLLLKMGARREKLVLS 459

Worm   353 LSFYGRYWENVNDNVPDEMFKEADLINGKAQGMFVAWKNLAGRG------WDKSE-------ALW 404
            :.|||:.:.                       :..|.:.|||.|      .|..|       ..:
  Fly   460 IPFYGQSFT-----------------------LATAHQILAGPGVAASGPGDAGELTKQPGMLAY 501

Worm   405 HEETQ--IPYIWNSEERKFFVF-------------ENERSLQAKMDYAADHNIGGVYIWALGADD 454
            :|..|  ..:.|.|:.....:|             |:..|.|||..|||::|..||..|.:..||
  Fly   502 YEICQRLTKFNWISDRNLNVIFGPFAMLNDQWVGYEDPTSAQAKARYAANNNFAGVAAWTIDLDD 566

Worm   455 NNDTLLN 461
            ..:...|
  Fly   567 FRNLCCN 573

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
chil-7	NP_496131.2	Glyco_18	127..453	CDD:214753	82/383 (21%)
Cht10	NP_001036422.1	Glyco_18	220..565	CDD:214753	82/383 (21%)
		GH18_chitolectin_chitotriosidase	221..586	CDD:119351	85/392 (22%)
		ChtBD2	697..737	CDD:214696
		CBM_14	801..848	CDD:279884
		CBM_14	875..918	CDD:279884
		Glyco_18	966..1310	CDD:214753
		GH18_chitolectin_chitotriosidase	967..1331	CDD:119351
		Glyco_18	1410..1753	CDD:214753
		GH18_chitolectin_chitotriosidase	1411..1774	CDD:119351
		ChtBD2	1834..1871	CDD:214696
		Glyco_18	1909..2253	CDD:214753
		GH18_chitolectin_chitotriosidase	1910..2274	CDD:119351
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160164207
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D826687at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm4747
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.750