DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment chil-5 and Cht10

DIOPT Version :9

Sequence 1:	NP_496127.1	Gene:	chil-5 / 182435	WormBaseID:	WBGene00007470	Length:	459	Species:	Caenorhabditis elegans
Sequence 2:	NP_001036422.1	Gene:	Cht10 / 3355116	FlyBaseID:	FBgn0250907	Length:	2286	Species:	Drosophila melanogaster

Alignment Length:	413	Identity:	92/413 - (22%)
Similarity:	166/413 - (40%)	Gaps:	94/413 - (22%)

- Green bases have known domain annotations that are detailed below.

Worm    91 PKHLIQESHQTISPPAAFCGKRIVGYF---AEFENAGLSRKQL------HMLTHIIYLFA----- 141
            |.|:::|  :.|.........:|:.||   |.:...|  .|.|      .:.|||||.||
  Fly  1391 PNHVLEE--ENIEATEMATEFKIICYFTNWAWYRQGG--GKFLPEDIDSDLCTHIIYGFAVLSRD 1451

Worm   142 ----RPTNGVITLDGEQTRRKFEEMKSKAREASSTLKVMISVGG--HDYYKEYSRLVSNETSRNV 200
                :|.:....||     .||.|.....|:..:  ||.:::||  .....:|||||.|..:|:.
  Fly  1452 NLTIQPHDSWADLD-----NKFYERIVAYRKKGA--KVTVAIGGWNDSAGDKYSRLVRNPEARSR 1509

Worm   201 FVKSIVSFFKKNDIDGIEIFWTRP----------KYEDIKSYSSFIQELRSAFTELQKRWNRKNE 255
            |:::::.|.::.:.||:::.|..|          ..|:...:|:.::||..||        :...
  Fly  1510 FIRNVLDFIEEYNFDGLDLDWEYPVCWQVDCKKGTAEEKIGFSALVRELFYAF--------QPRG 1566

Worm   256 YIISLIV-PKEK--HWSFDLKDFSKFVDFFNIYSTQFR---EKQVGPDSPLY----GGEGRNIDE 310
            .|:|..| |.:|  ...:::.:.|.:..:.::.:..:.   :|:.|..:|:|    |....|.:.
  Fly  1567 LILSAAVSPNKKVIDAGYEVAELSHYFSWISVMAYDYHGQWDKKTGHVAPMYSHPEGTANFNANF 1631

Worm   311 TMKYYICKTGQPSKFNIMVSFHGTFWEGAE-----LPLRDYSDDIWKEKNVARGPFAV------- 363
            :|.|:|.......|..:.:..:|..:..||     |....|......|...|||..|.
  Fly  1632 SMNYWISMGADRRKLVMGIPLYGQSFSLAETTKHQLNAPTYGGGEAGEATRARGFLAYYEICLKI 1696

Worm   364 ---RWRHLRQRNWNLTDIKFHNLTKTSYIWIPGPPTWFLTLEDEKSLREKNRYVADHNIGGITMW 425
               ||..:|.....:....:|.            ..| ::.:|...:|.|:.|:....:||..:|
  Fly  1697 RHHRWNVVRDTKGRIGPFAYHG------------DQW-VSFDDVPMIRHKSEYIKAMGLGGAMIW 1748

Worm   426 TIDQDD-------DDHTLLKVVS 441
            .:|.||       :.:.|||.::
  Fly  1749 ALDLDDFKNVCECESYPLLKAIN 1771

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
chil-5	NP_496127.1	Glyco_18	112..430	CDD:214753	83/372 (22%)
Cht10	NP_001036422.1	Glyco_18	220..565	CDD:214753
		GH18_chitolectin_chitotriosidase	221..586	CDD:119351
		ChtBD2	697..737	CDD:214696
		CBM_14	801..848	CDD:279884
		CBM_14	875..918	CDD:279884
		Glyco_18	966..1310	CDD:214753
		GH18_chitolectin_chitotriosidase	967..1331	CDD:119351
		Glyco_18	1410..1753	CDD:214753	83/372 (22%)
		GH18_chitolectin_chitotriosidase	1411..1774	CDD:119351	88/391 (23%)
		ChtBD2	1834..1871	CDD:214696
		Glyco_18	1909..2253	CDD:214753
		GH18_chitolectin_chitotriosidase	1910..2274	CDD:119351
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160164204
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm4747
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.740