Protein Alignment Dusp8 and MKP-4

DIOPT Version :10

• Sequence 1: NP_032774.1
• Gene: Dusp8 / 18218
• MGIID: 106626
• Length: 663
• Species: Mus musculus
• Sequence 2: NP_608332.2
• Gene: MKP-4 / 32963
• FlyBaseID: FBgn0031044
• Length: 387
• Species: Drosophila melanogaster
• Alignment Length: 322
• Identity: 73/322 - (22%)
• Similarity: 114/322 - (35%)
• Gaps: 97/322 - (30%)

Mouse   159 VGLTRILPHLYLGSQKDVLNKDLMTQNGISYVLNASNSCPKPDFICESRFMR---IPINDNYCEK 220
            |.:..:...|:||:.....:.:.:....|:::|.. :|.|.|..|.|:.|:.   |.|.|...|.
  Fly    37 VSIDEVDTGLFLGNLTAATHMETLRSFKITHILTL-DSVPLPQHILEASFLTTKYIQIADMPRED 100

Mouse   221 LLPWLDKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPSISP 285
            :|..|:..::||..|......|:|||..|:|||::..|||:||...:....||..||.:|..:.|
  Fly   101 ILQHLEGCVDFISSALAQQGNVLVHCYFGVSRSSSTVIAYMMKRHNLDFLPAYELVKAKRRFVQP 165

Mouse   286 NFNFLGQLL-------------------------EYERSLKLL-----AALQTDGPHL--GTPEP 318
            |..|:.||.                         |..|..|:|     :.::.| |.:  ..|||
  Fly   166 NAGFVSQLKLFRRMGCKIDPNCQRYKIHRLRLAGEQMRKAKILPQSFHSVVRPD-PDITRENPEP 229

Mouse   319 LM-------------------GPAAGIPLPRLPPSTSESAATGSEAATAAREGSPSAGGDAPIPS 364
            ::                   .|....|...:|....|.||                   |.:|:
  Fly   230 IVFRCRRCRRVLASKSHVLEHKPRDRPPQEVVPKEKEEVAA-------------------AKLPA 275

Mouse   365 TAPATSALQQGLRGLHLSSDRLQDTNRLKRSFSLDIKSAYAPSRRPDFPGPPDPGEAPKLCK 426
            .:...:....|.|.|...|:|:       |..||               |.|.....|..|:
  Fly   276 QSHDQAENHHGARMLEQLSERI-------RQSSL---------------GSPGHESTPNYCR 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dusp8	NP_032774.1	DSP_MapKP	10..137	CDD:238723
		DSP_DUSP8	150..300	CDD:350493	46/168 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	313..367		11/74 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	404..624		4/23 (17%)
MKP-4	NP_608332.2	DSP	39..175	CDD:350348	43/136 (32%)