| Sequence 1: | NP_000205.1 | Gene: | JAG1 / 182 | HGNCID: | 6188 | Length: | 1218 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_062020.2 | Gene: | Jag1 / 29146 | RGDID: | 2937 | Length: | 1219 | Species: | Rattus norvegicus |
| Alignment Length: | 1219 | Identity: | 1176/1219 - (96%) |
|---|---|---|---|
| Similarity: | 1193/1219 - (97%) | Gaps: | 1/1219 - (0%) |
- Green bases have known domain annotations that are detailed below.
|
Human 1 MRSPRTRGRSGRPLSLLLALLCALRAKVCGASGQFELEILSMQNVNGELQNGNCCGGARNPGDRK 65
Human 66 CTRDECDTYFKVCLKEYQSRVTAGGPCSFGSGSTPVIGGNTFNLKASRGNDRNRIVLPFSFAWPR 130
Human 131 SYTLLVEAWDSSNDTVQPDSIIEKASHSGMINPSRQWQTLKQNTGVAHFEYQIRVTCDDYYYGFG 195
Human 196 CNKFCRPRDDFFGHYACDQNGNKTCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGL 260
Human 261 YCDKCIPHPGCVHGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCP 325
Human 326 EGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQ 390
Human 391 DLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCL 455
Human 456 GQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGN 520
Human 521 LCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASN 585
Human 586 DTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNS 650
Human 651 YKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCN 715
Human 716 NGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICA 780
Human 781 QNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCV 845
Human 846 CPPGHSGAKCQEVSGRPCITMGSVIPDGAKWDDDCNTCQCLNGRIACSKVWCGPRPCLLHKGHSE 910
Human 911 CPSGQSCIPILDDQCFVHPCTGVGECRSSSLQPVKTKCTSDSYYQDNCANITFTFNKEMMSPGLT 975
Human 976 TEHICSELRNLNILKNVSAEYSIYIACEPSPSANNEIHVAISAEDIRDDGNPIKEITDKIIDLVS 1040
Human 1041 KRDGNSSLIAAVAEVRVQRRPLKNRTDFLVPLLSSVLTVAWICCLVTAFYWCLRK-RRKPGSHTH 1104
Human 1105 SASEDNTTNNVREQLNQIKNPIEKHGANTVPIKDYENKNSKMSKIRTHNSEVEEDDMDKHQQKAR 1169
Human 1170 FAKQPAYTLVDREEKPPNGTPTKHPNWTNKQDNRDLESAQSLNRMEYIV 1218 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| JAG1 | NP_000205.1 | MNNL | 32..185 | CDD:462222 | 150/152 (99%) |
| DSL | 167..229 | CDD:128366 | 59/61 (97%) | ||
| Important for interaction with NOTCH1. /evidence=ECO:0000269|PubMed:18660822 | 199..207 | 7/7 (100%) | |||
| EGF_CA | 296..334 | CDD:238011 | 36/37 (97%) | ||
| EGF | 340..370 | CDD:394967 | 28/29 (97%) | ||
| EGF_CA | 374..410 | CDD:238011 | 35/35 (100%) | ||
| EGF_CA | 412..447 | CDD:238011 | 33/34 (97%) | ||
| EGF_CA | 450..485 | CDD:238011 | 34/34 (100%) | ||
| EGF_CA | 487..523 | CDD:238011 | 35/35 (100%) | ||
| EGF_CA | 525..560 | CDD:238011 | 34/34 (100%) | ||
| EGF_CA | 629..665 | CDD:238011 | 32/35 (91%) | ||
| EGF_CA | 667..702 | CDD:238011 | 33/34 (97%) | ||
| EGF | 748..777 | CDD:394967 | 27/28 (96%) | ||
| EGF_CA | 782..817 | CDD:238011 | 34/34 (100%) | ||
| EGF_CA | 820..856 | CDD:238011 | 33/35 (94%) | ||
| VWC_out | 863..930 | CDD:214565 | 58/66 (88%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1152..1218 | 61/65 (94%) | |||
| Jag1 | NP_062020.2 | MNNL | 32..185 | CDD:462222 | 150/152 (99%) |
| DSL | 167..229 | CDD:128366 | 59/61 (97%) | ||
| Important for interaction with NOTCH1. /evidence=ECO:0000250 | 199..207 | 7/7 (100%) | |||
| EGF_CA | 296..334 | CDD:238011 | 36/37 (97%) | ||
| EGF | 340..370 | CDD:394967 | 28/29 (97%) | ||
| EGF_CA | 374..410 | CDD:238011 | 35/35 (100%) | ||
| EGF_CA | 412..447 | CDD:238011 | 33/34 (97%) | ||
| EGF_CA | 450..485 | CDD:238011 | 34/34 (100%) | ||
| EGF_CA | 487..523 | CDD:238011 | 35/35 (100%) | ||
| EGF_CA | 525..560 | CDD:238011 | 34/34 (100%) | ||
| EGF_CA | 629..665 | CDD:238011 | 32/35 (91%) | ||
| EGF_CA | 667..702 | CDD:238011 | 33/34 (97%) | ||
| EGF_CA | <714..740 | CDD:238011 | 23/25 (92%) | ||
| EGF | 748..777 | CDD:394967 | 27/28 (96%) | ||
| EGF_CA | 782..817 | CDD:238011 | 34/34 (100%) | ||
| EGF_CA | 820..855 | CDD:238011 | 32/34 (94%) | ||
| VWC_out | 863..930 | CDD:214565 | 58/66 (88%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1182..1219 | 34/36 (94%) |