| Sequence 1: | NP_000205.1 | Gene: | JAG1 / 182 | HGNCID: | 6188 | Length: | 1218 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_038850.1 | Gene: | Jag1 / 16449 | MGIID: | 1095416 | Length: | 1218 | Species: | Mus musculus |
| Alignment Length: | 1218 | Identity: | 1176/1218 - (96%) |
|---|---|---|---|
| Similarity: | 1194/1218 - (98%) | Gaps: | 0/1218 - (0%) |
- Green bases have known domain annotations that are detailed below.
|
Human 1 MRSPRTRGRSGRPLSLLLALLCALRAKVCGASGQFELEILSMQNVNGELQNGNCCGGARNPGDRK 65
Human 66 CTRDECDTYFKVCLKEYQSRVTAGGPCSFGSGSTPVIGGNTFNLKASRGNDRNRIVLPFSFAWPR 130
Human 131 SYTLLVEAWDSSNDTVQPDSIIEKASHSGMINPSRQWQTLKQNTGVAHFEYQIRVTCDDYYYGFG 195
Human 196 CNKFCRPRDDFFGHYACDQNGNKTCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGL 260
Human 261 YCDKCIPHPGCVHGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCP 325
Human 326 EGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQ 390
Human 391 DLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCL 455
Human 456 GQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGN 520
Human 521 LCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASN 585
Human 586 DTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNS 650
Human 651 YKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCN 715
Human 716 NGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICA 780
Human 781 QNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCV 845
Human 846 CPPGHSGAKCQEVSGRPCITMGSVIPDGAKWDDDCNTCQCLNGRIACSKVWCGPRPCLLHKGHSE 910
Human 911 CPSGQSCIPILDDQCFVHPCTGVGECRSSSLQPVKTKCTSDSYYQDNCANITFTFNKEMMSPGLT 975
Human 976 TEHICSELRNLNILKNVSAEYSIYIACEPSPSANNEIHVAISAEDIRDDGNPIKEITDKIIDLVS 1040
Human 1041 KRDGNSSLIAAVAEVRVQRRPLKNRTDFLVPLLSSVLTVAWICCLVTAFYWCLRKRRKPGSHTHS 1105
Human 1106 ASEDNTTNNVREQLNQIKNPIEKHGANTVPIKDYENKNSKMSKIRTHNSEVEEDDMDKHQQKARF 1170
Human 1171 AKQPAYTLVDREEKPPNGTPTKHPNWTNKQDNRDLESAQSLNRMEYIV 1218 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| JAG1 | NP_000205.1 | MNNL | 32..106 | CDD:284966 | 72/73 (99%) |
| DSL | 167..229 | CDD:279722 | 59/61 (97%) | ||
| Important for interaction with NOTCH1. /evidence=ECO:0000269|PubMed:18660822 | 199..207 | 7/7 (100%) | |||
| EGF_CA | 296..334 | CDD:238011 | 36/37 (97%) | ||
| EGF | 340..370 | CDD:278437 | 28/29 (97%) | ||
| EGF_CA | 374..410 | CDD:238011 | 35/35 (100%) | ||
| EGF_CA | 412..447 | CDD:238011 | 33/34 (97%) | ||
| EGF_CA | 450..485 | CDD:238011 | 34/34 (100%) | ||
| EGF_CA | 487..523 | CDD:238011 | 35/35 (100%) | ||
| EGF_CA | 525..560 | CDD:238011 | 34/34 (100%) | ||
| EGF_CA | 629..665 | CDD:238011 | 33/35 (94%) | ||
| EGF_CA | 667..702 | CDD:238011 | 33/34 (97%) | ||
| EGF | 748..777 | CDD:278437 | 27/28 (96%) | ||
| EGF_CA | 782..817 | CDD:238011 | 34/34 (100%) | ||
| EGF_CA | 820..856 | CDD:238011 | 33/35 (94%) | ||
| VWC_out | 863..930 | CDD:214565 | 58/66 (88%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1152..1218 | 61/65 (94%) | |||
| Jag1 | NP_038850.1 | MNNL | 32..106 | CDD:284966 | 72/73 (99%) |
| DSL | 167..229 | CDD:279722 | 59/61 (97%) | ||
| Important for interaction with NOTCH1. /evidence=ECO:0000250 | 199..207 | 7/7 (100%) | |||
| EGF_CA | 296..334 | CDD:238011 | 36/37 (97%) | ||
| EGF | 340..370 | CDD:278437 | 28/29 (97%) | ||
| EGF_CA | 374..410 | CDD:238011 | 35/35 (100%) | ||
| EGF_CA | 412..447 | CDD:238011 | 33/34 (97%) | ||
| EGF_CA | 450..485 | CDD:238011 | 34/34 (100%) | ||
| EGF_CA | 487..523 | CDD:238011 | 35/35 (100%) | ||
| EGF_CA | 525..560 | CDD:238011 | 34/34 (100%) | ||
| EGF_CA | 629..665 | CDD:238011 | 33/35 (94%) | ||
| EGF_CA | 667..702 | CDD:238011 | 33/34 (97%) | ||
| EGF_CA | <714..740 | CDD:238011 | 23/25 (92%) | ||
| EGF | 748..777 | CDD:278437 | 27/28 (96%) | ||
| EGF_CA | 782..817 | CDD:238011 | 34/34 (100%) | ||
| EGF_CA | 820..855 | CDD:238011 | 32/34 (94%) | ||
| VWC_out | 863..930 | CDD:214565 | 58/66 (88%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1181..1218 | 34/36 (94%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C83973380 | |
| Domainoid | 1 | 1.000 | 730 | 1.000 | Domainoid score | I3485 |
| eggNOG | 1 | 0.900 | - | - | E33208_3BAFT | |
| HGNC | 1 | 1.500 | - | - | ||
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H180 | |
| Inparanoid | 1 | 1.050 | 2649 | 1.000 | Inparanoid score | I810 |
| Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S3686 |
| NCBI | 1 | 1.000 | - | - | ||
| OMA | 1 | 1.010 | - | - | QHG45993 | |
| OrthoDB | 1 | 1.010 | - | - | D197806at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0003067 | |
| OrthoInspector | 1 | 1.000 | - | - | oto128221 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_105778 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR24044 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R6119 |
| SonicParanoid | 1 | 1.000 | - | - | X2046 | |
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 1 | 0.960 | - | - | ||
| 20 | 20.250 | |||||