Protein Alignment Npr3 and Gyc76C

DIOPT Version :9

• Sequence 1: NP_032754.2
• Gene: Npr3 / 18162
• MGIID: 97373
• Length: 536
• Species: Mus musculus
• Sequence 2: NP_001163473.1
• Gene: Gyc76C / 8674026
• FlyBaseID: FBgn0266136
• Length: 1525
• Species: Drosophila melanogaster
• Alignment Length: 579
• Identity: 118/579 - (20%)
• Similarity: 223/579 - (38%)
• Gaps: 139/579 - (24%)

Mouse     4 LLLFTFSA--CVLLARVLLAGGASSGAGDTRPGSRRRAREALAAQKIEVLVL--LPRDDSYLFSL 64
            |||.:.:.  |.....||..|..::..||.      :.|:.||......:.|  :.:|.:.|
  Fly     9 LLLLSVAVRDCSNHRTVLTVGYLTALTGDL------KTRQGLAISGALTMALDEVNKDPNLL--- 64

Mouse    65 ARVRPAIEYALRSVEGNGTGRKLLPPGTRFQVAYEDSDCGNRALFSLV-DRVAAARGAKPDLILG 128
                |.:...||..:..|                 |:....:|:..:: |.:|...|.:     |
  Fly    65 ----PNVYLDLRWNDTKG-----------------DTVLATKAITEMICDGIATIFGPE-----G 103

Mouse   129 PVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDTEY-----SHLTRVAPAYAKMGEMMLALFR 188
            | | |..|.|::..   ::||:|         :|..||     ....|..|...::.:.:|||.|
  Fly   104 P-C-YVEAIVSQSR---NIPMIS---------YKCAEYRASAIPTFARTEPPDTQVVKSLLALLR 154

Mouse   189 HHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGL-------HTSAYNFDETKDLD--LD---- 240
            ::.|::.:::|.|         ....|.::.:::..       |..::..:..|..:  ||
  Fly   155 YYAWNKFSILYED---------VWSPVADLLKDQATKRNMTINHKQSFIDNRVKCCEQMLDCCRS 210

Mouse   241 ----DIVRYIQGSERVVIMCASGDTIRRIMLAVHRHGM-TSGDYAFFNIELF-NSSSYGDGSWRR 299
                .:|:......|:.:...:.:::...|.::...|: ..|:|....:::. .|....:...||
  Fly   211 GYWYQLVQNTMNRTRIYVFLGAANSLVDFMSSMETAGLFARGEYMVIFVDMMVYSEREAEKYLRR 275

Mouse   300 GDK-------HDSE-AKQAYSSLQTVTLLRTVKPEFEKFSMEVKSSVEKQGLNEE---------- 346
            .|:       |.:| ..|...||..|......| ::.:|:.:|:....|...|.|
  Fly   276 VDQITFMSNCHSTENFNQMARSLLVVASTPPTK-DYIQFTKQVQKYSSKPPFNLEIPRLFVESNF 339

Mouse   347 -DYVNMFVEGFHDAILLYVLALHEVLRAGYS----------KKDGGKIIQQ-TWNRTFEGIAG-Q 398
             .:::::....:|::.||..|:.::||....          ..:|.::|.. ..|||:..|.| :
  Fly   340 SKFISIYAAYLYDSVKLYAWAVDKMLREETRVLTDDVIFEVASNGTRVIDTIIKNRTYMSITGSK 404

Mouse   399 VSIDANGDRYGDFSVVA--------MTDTEAGTQEVIGDYF--GKE-GRFQM-RSNVKYPWGPLK 451
            :.||..||..|:|||:|        ..:.......|...||  |:| ..::: ..::.:|.|..|
  Fly   405 IKIDQYGDSEGNFSVLAYKPHKWNNSNNMPCNYHMVPVAYFHQGEEHPEYKLINGSIDWPSGGEK 469

Mouse   452 LRLDETRIVEHTNSSPCKSSGGLEESAVTGIVVGALL--GAGLLMAFYFFRKKYRITIE 508
             ..||. :....|.. ||.......|.|..:|:|.||  ...:.|:.|   :|::|.:|
  Fly   470 -PADEP-MCGFANEL-CKKDDTHYTSTVAAVVLGVLLFCSGVITMSIY---RKWKIELE 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Npr3	NP_032754.2	PBP1_NPR_C_like	49..440	CDD:107381	87/460 (19%)
		ANF_receptor	66..419	CDD:279440	79/416 (19%)
		TM_EphA1	471..502	CDD:214014	8/32 (25%)
Gyc76C	NP_001163473.1	PBP1_Speract_GC_like	26..445	CDD:107365	90/477 (19%)
		ANF_receptor	48..412	CDD:279440	75/416 (18%)
		PK_GC-A_B	543..827	CDD:270944
		HNOBA	<835..881	CDD:285003
		CYCc	860..1052	CDD:214485
		Guanylate_cyc	887..1074	CDD:278633

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810