Protein Alignment C18B12.4 and gzl

DIOPT Version :10

• Sequence 1: NP_510498.1
• Gene: C18B12.4 / 181600
• WormBaseID: WBGene00007666
• Length: 456
• Species: Caenorhabditis elegans
• Sequence 2: NP_649653.1
• Gene: gzl / 40791
• FlyBaseID: FBgn0037442
• Length: 536
• Species: Drosophila melanogaster
• Alignment Length: 450
• Identity: 112/450 - (24%)
• Similarity: 178/450 - (39%)
• Gaps: 137/450 - (30%)

 Worm    97 AFVSRSNISHPCKFSHQAFMVQNSTYPFRLVIFYNYPGQEPISMEGTELRDKVNIPVLMISHACK 161
            |.|:|..    |.|..:..:.||::|  ..||.||..|.:...|....:.. :.||.:.:.|...
  Fly    91 ALVARGE----CVFERKIRVAQNASY--SAVIVYNNEGDDLEQMSAENITG-IRIPSVFVGHTTG 148

 Worm   162 EEIAKKF--------SDTAGYRLRVRIDPGYYELFRYLIPFLVVIVFCF---ALFLITLCVRGCV 215
            :.:|..|        :|...:.:..::          ::||.::|..||   .:::|..|:|
  Fly   149 KALATYFTTEVVLIINDELPFNINTQL----------ILPFSILIGMCFIIMVIYMIYKCIR--- 200

 Worm   216 ERRKLNKRRLSKRNLKKIPVKKY---RLGDDPDTCAICLESFASGEKLRHLPCRHVFHCNCIDVW 277
            |:|:|.:.||.|..|||:||.:|   ...:..|||.||||.|...:|||.|||.|.:|.:|||.|
  Fly   201 EQRRLRRHRLPKSMLKKLPVLRYTKNNANNKYDTCVICLEDFIEDDKLRVLPCSHPYHTHCIDPW 265

 Worm   278 LTQTRKICPLCKRKIGTDSDSECSTN---DLASTSQGPNDATALYNNADNQSGFELPVPQGQMVD 339
            ||:.|::||:||||:.|..::..|.:   .|.:.:...:|.|.|... ...:|.::    ||:..
  Fly   266 LTENRRVCPICKRKVFTKGEARASRSRQPSLDNVTDTDDDTTPLLQQ-QQSNGRQV----GQVSS 325

 Worm   340 LWSSQEALVDQDIVL---------HNTTRRSITGFVRNAFRKLRNSPRHRDVDVHSGLEGGSYLV 395
            ..|:..|......|.         |.|.||...|  ||.|.:.::|      |..:.|...:  |
  Fly   326 ASSAGGAAGSSSSVAAAAVAGTTRHGTFRRGHAG--RNPFEESQSS------DDENALLAST--V 380

 Worm   396 RQQTTSNDND-------------HLLEN------------------------------------- 410
            |..|:|..::             ||.|.
  Fly   381 RPATSSGAHERINPFDRAPNLPAHLAEQLTESRRSVWSRINFASFFRRQPAVISVAAPPYLERVE 445

 Worm   411 --------------EVSDPTSSSELN------------IPSSEELTVPTSISTHSLDTAT 444
                          .|:.|.|::.||            :|....:..|.:|||.:.|:||
  Fly   446 SGTSAMGLPVTGTIAVASPASNNILNPNLSGSFKDEDDMPPHRSIYEPIAISTPAADSAT 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
C18B12.4	NP_510498.1	PA	<74..176	CDD:333703	20/86 (23%)
		HRD1	<223..>335	CDD:227568	45/117 (38%)
		RING-H2_RNF103	242..295	CDD:438136	29/52 (56%)
gzl	NP_649653.1	PA_C_RZF_like	14..171	CDD:239038	20/86 (23%)
		RING-H2_RNF13-like	233..278	CDD:438327	26/44 (59%)