Protein Alignment DRD5 and Octbeta1R

DIOPT Version :9

• Sequence 1: NP_000789.1
• Gene: DRD5 / 1816
• HGNCID: 3026
• Length: 477
• Species: Homo sapiens
• Sequence 2: NP_001262843.1
• Gene: Octbeta1R / 42652
• FlyBaseID: FBgn0038980
• Length: 508
• Species: Drosophila melanogaster
• Alignment Length: 400
• Identity: 131/400 - (32%)
• Similarity: 203/400 - (50%)
• Gaps: 73/400 - (18%)

Human    24 GNAVG-GSAGAPPL-----GPSQVVTA--------------------C-LLTLLIIWTLLGNVLV 61
            |:||| ||:.|..:     |.:|.:.|                    | ::..:|:..:|||:||
  Fly    64 GSAVGSGSSIAVSVEDVVAGQAQDIQASEGSTDDADGSSHLALVFVKCFIIGFIILAAILGNMLV 128

Human    62 CAAIVRSRHLRANMTNVFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFGA-FCDVWVAFDIMCST 125
            ..:::|.|.||. :||.|:|||||:|:.|||..|.:.|...::|.|.||: .||:|.:||:..||
  Fly   129 IVSVMRHRKLRI-ITNYFVVSLAVADMLVALCAMTFNASVMISGKWMFGSVMCDMWNSFDVYFST 192

Human   126 ASILNLCVISVDRYWAISRPFRYKRKMTQRMALVMVGLAWTLSILISFIPVQLNWHRDQAASWGG 190
            |||::||.||||||:||.:|..|...||||...:|:.:.|....|:||:|:
  Fly   193 ASIMHLCCISVDRYYAIVQPLDYPLIMTQRRVFIMLLMVWLSPALLSFLPI-------------- 243

Human   191 LDLPNNLANWTPWEEDFWEPDVNAENCDSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQ 255
                  .:.|....|::.....|...|:..:|:.|||.||.:||:||..:|:..|.|||:.|..|
  Fly   244 ------CSGWYTTTENYKYLKSNPHICEFKVNKAYAIVSSSMSFWIPGIVMLSMYYRIYQEADRQ 302

Human   256 IRRISS-------LERAAEHAQSCRSSAACAPDTSLRASIKKETKVLKTLSVIMGVFVCCWLPFF 313
            .|.:..       ||:..:.:|..:...:...:.|..:::::|.|..:||.:||..|:.||||||
  Fly   303 ERLVYRSKVAALLLEKHLQISQIPKPRPSIQVEQSTISTMRRERKAARTLGIIMSAFLICWLPFF 367

Human   314 ILNCMVPFCSGHPEGPPAGFPCVS-ETTFDVFVWFGWANSSLNPVIYA-FNADFQKVFAQLLG-- 374
            :...:...|..          |:: .....:..|.|:.||:|||:||| ||.||:..|.:.|.
  Fly   368 LWYIVSSLCDS----------CITPRLLVGILFWIGYFNSALNPIIYAYFNRDFRAAFKKTLKSL 422

Human   375 ---CSHFCSR 381
               ..:||.|
  Fly   423 FPYAFYFCRR 432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DRD5	NP_000789.1	7tm_1	57..359	CDD:278431	106/310 (34%)
		7tm_4	<123..>175	CDD:304433	26/51 (51%)
Octbeta1R	NP_001262843.1	7tm_4	112..>231	CDD:304433	55/119 (46%)
		7tm_1	124..404	CDD:278431	106/310 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24248
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	3	2.970