| Sequence 1: | NP_000788.2 | Gene: | DRD4 / 1815 | HGNCID: | 3025 | Length: | 419 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_031904.1 | Gene: | Drd4 / 13491 | MGIID: | 94926 | Length: | 387 | Species: | Mus musculus |
| Alignment Length: | 419 | Identity: | 307/419 - (73%) |
|---|---|---|---|
| Similarity: | 324/419 - (77%) | Gaps: | 32/419 - (7%) |
- Green bases have known domain annotations that are detailed below.
|
Human 1 MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVATERAL 65
Human 66 QTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCTASIFNLCAIS 130
Human 131 VDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGRDPAVCRLEDRDYVVY 195
Human 196 SSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSGPGPPSPTPPAPRLPQDPCGP 260
Human 261 DCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPGLPPDPCGSNCAPPDAVRAAALPPQT 325
Human 326 PPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWTPFFVVHITQALCPACSVPPRLVSAVTWLGY 390
Human 391 VNSALNPVIYTVFNAEFRNVFRKALRACC 419 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| DRD4 | NP_000788.2 | 7tmA_D4_dopamine_R | 38..411 | CDD:320434 | 278/372 (75%) |
| TM helix 1 | 38..62 | CDD:320434 | 22/23 (96%) | ||
| TM helix 2 | 69..95 | CDD:320434 | 23/25 (92%) | ||
| TM helix 3 | 108..138 | CDD:320434 | 28/29 (97%) | ||
| TM helix 4 | 150..173 | CDD:320434 | 17/22 (77%) | ||
| TM helix 5 | 189..218 | CDD:320434 | 27/28 (96%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 230..264 | 20/33 (61%) | |||
| 4 X 16 AA approximate tandem repeats of [PA]-A-P-G-L-P-[PQR]-[DG]-P-C-G-P-D-C-A-P | 249..312 | 17/62 (27%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 317..336 | 9/18 (50%) | |||
| TM helix 6 | 339..369 | CDD:320434 | 28/29 (97%) | ||
| TM helix 7 | 379..404 | CDD:320434 | 22/24 (92%) | ||
| Drd4 | NP_031904.1 | 7tm_1 | 48..368 | CDD:278431 | 257/348 (74%) |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 224..247 | 17/27 (63%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 287..306 | 11/18 (61%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C83954779 | |
| Domainoid | 1 | 1.000 | 498 | 1.000 | Domainoid score | I7768 |
| eggNOG | 1 | 0.900 | - | - | E33208_3BBW6 | |
| HGNC | 1 | 1.500 | - | - | ||
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H20215 | |
| Inparanoid | 1 | 1.050 | 582 | 1.000 | Inparanoid score | I10856 |
| Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S5931 |
| NCBI | 1 | 1.000 | - | - | ||
| OMA | 1 | 1.010 | - | - | QHG43800 | |
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 1 | 1.000 | - | - | FOG0008323 | |
| OrthoInspector | 1 | 1.000 | - | - | oto126372 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_119968 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR24247 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R10426 |
| SonicParanoid | 1 | 1.000 | - | - | X6305 | |
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 1 | 0.960 | - | - | ||
| 19 | 19.240 | |||||