| Sequence 1: | NP_000786.1 | Gene: | DRD2 / 1813 | HGNCID: | 3023 | Length: | 443 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001014758.2 | Gene: | Dop2R / 33007 | FlyBaseID: | FBgn0053517 | Length: | 905 | Species: | Drosophila melanogaster |
| Alignment Length: | 541 | Identity: | 179/541 - (33%) |
|---|---|---|---|
| Similarity: | 249/541 - (46%) | Gaps: | 144/541 - (26%) |
- Green bases have known domain annotations that are detailed below.
|
Human 34 YNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVG 98
Human 99 EWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLS 163
Human 164 FTISCPLLFGLNNADQNE---CIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNT 225
Human 226 KRSSRAFRAHLRAPLKG----------------------------------------------NC 244
Human 245 THPE-------------DMKLCTVIMKSNGSFPV---------------NRRRVEAARRAQEL-- 279
Human 280 -----------EMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSP--AKPEKNGHA 331
Human 332 KDHPKIAK---------IFEIQTMP-NGKT-RTSLKTMSRR------------------------ 361
Human 362 KLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHC-----DCNIPPVLYSAFTWLGYVNSAV 421
Human 422 NPIIYTTFNIEFRKAFLKILH 442 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| DRD2 | NP_000786.1 | 7tmA_D2_dopamine_R | 35..437 | CDD:320435 | 174/533 (33%) |
| TM helix 1 | 37..61 | CDD:320435 | 9/23 (39%) | ||
| TM helix 2 | 70..92 | CDD:320435 | 16/21 (76%) | ||
| TM helix 3 | 108..130 | CDD:320435 | 10/21 (48%) | ||
| TM helix 4 | 154..170 | CDD:320435 | 5/15 (33%) | ||
| TM helix 5 | 187..210 | CDD:320435 | 9/22 (41%) | ||
| Interaction with PPP1R9B. /evidence=ECO:0000250 | 211..373 | 51/285 (18%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 281..332 | 15/52 (29%) | |||
| TM helix 6 | 372..394 | CDD:320435 | 15/21 (71%) | ||
| TM helix 7 | 405..430 | CDD:320435 | 14/24 (58%) | ||
| Dop2R | NP_001014758.2 | 7tmA_D2-like_dopamine_R | 376..>565 | CDD:320181 | 88/189 (47%) |
| TM helix 1 | 377..403 | CDD:320181 | 10/25 (40%) | ||
| TM helix 2 | 410..436 | CDD:320181 | 19/25 (76%) | ||
| TM helix 3 | 448..478 | CDD:320181 | 17/29 (59%) | ||
| TM helix 4 | 490..513 | CDD:320181 | 9/22 (41%) | ||
| TM helix 5 | 529..558 | CDD:320181 | 12/28 (43%) | ||
| 7tm_GPCRs | <822..898 | CDD:333717 | 43/75 (57%) | ||
| TM helix 6 | 825..850 | CDD:320095 | 17/24 (71%) | ||
| TM helix 7 | 866..891 | CDD:320095 | 14/24 (58%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 246 | 1.000 | Domainoid score | I2175 |
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 282 | 1.000 | Inparanoid score | I2884 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 1 | 1.000 | - | - | FOG0003003 | |
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 1 | 0.900 | - | - | OOG6_108090 | |
| Panther | 1 | 1.100 | - | - | O | PTHR24248 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R4544 |
| SonicParanoid | 1 | 1.000 | - | - | X1733 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 9 | 8.990 | |||||