Protein Alignment Nos2 and CG14882

DIOPT Version :10

• Sequence 1: NP_035057.1
• Gene: Nos2 / 18126
• MGIID: 97361
• Length: 1144
• Species: Mus musculus
• Sequence 2: NP_650544.1
• Gene: CG14882 / 41994
• FlyBaseID: FBgn0038429
• Length: 454
• Species: Drosophila melanogaster
• Alignment Length: 430
• Identity: 116/430 - (26%)
• Similarity: 195/430 - (45%)
• Gaps: 59/430 - (13%)

Mouse   719 SSIHAKNVFTMRLKSQQNLQSEKSSRTTLLVQLTFEGSRGPSYLPGEHLGIFPGNQTALVQGILE 783
            ||:..|       :|:..:.::|::.|..:|:||.|.:.  .|.||:.:||.|.|:...|:.:|.
  Fly    57 SSVEIK-------ESKVLVSADKATETKRVVELTLESTF--DYQPGDTIGILPANKLEQVESLLH 112

Mouse   784 RVVDCPTPHQTVCLEVLDESGSYW---------VKDKRLP---PCSLS--QALTYFLDITTPPTQ 834
            |            ||:||::.:..         .|:.:||   |.:.:  :.||:.|.:...|.:
  Fly   113 R------------LELLDQADTTCHLKLVFNCANKNAKLPAHIPATTTPREILTHCLSLNFVPQK 165

Mouse   835 LQLHKLARFATDETDRQRLEALC--QPSE-YNDWKFSNNPTFLEVLEEFPSLHVPAAFLLSQLPI 896
            ..|..||.|.:|:.:|..|..|.  |.:| |..........|:::||...:...|.|||...||.
  Fly   166 QLLSALAGFTSDDKERCFLSCLSSKQATEYYQSLILEQGLLFIDILEVCVNCRPPLAFLAEHLPR 230

Mouse   897 LKPRYYSISSSQDHTPSEVHLTVAVVTYRTRDGQGPLHHGVCSTWIRNLKPQD------PVPCFV 955
            |.||.|||::|    |.|.......|.|....    |..||.::.:.....|.      .|..:.
  Fly   231 LLPRPYSIANS----PLEASNRELRVIYSLLS----LKPGVTTSMLEAAAQQSSPEHSKKVVIYP 287

Mouse   956 RSVSGFQLPE-DPSQPCILIGPGTGIAPFRSFWQQRLH-DSQHKGLKGGRMSLVFGCRHPEEDHL 1018
            |..:.|:..| |..:..|||..|||:|||..|...:.. ..|......|:..|..|.:.||. .|
  Fly   288 RMSNLFRYTERDVGRNQILIAVGTGLAPFLGFLAHKEELIKQQPQQPSGQSWLYIGAKTPEA-VL 351

Mouse  1019 YQEEMQEMVRKRVLFQVHTGYSRLPGKPKVYVQDILQKQLANEVLSVLHGEQGHLYICGD-VRMA 1082
            .:|::.|.....:|.::...|||  |:...|||.:|::. ..:::..|...:..||||.| .:::
  Fly   352 KREKLMEWQESSLLERLRMCYSR--GESPSYVQHMLEED-CEDLVEFLMKSETVLYICADGAKIS 413

Mouse  1083 RDVATTLKKLVATKLNLSEEQVEDYFFQLKSQKRYHEDIF 1122
            :.:|..|.:.:...::|:||:......:|:.|.:|.||::
  Fly   414 QSIAGVLSRCLQKAMHLTEEEASQLLKKLRKQDKYREDVW 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nos2	NP_035057.1	DINNN-motif, mediates interaction with SPSB1, SPSB2 and SPSB4. /evidence=ECO:0000269|PubMed:20603330	23..27
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..59
		NOS_oxygenase_euk	78..490	CDD:238410
		Calmodulin-binding. /evidence=ECO:0000250|UniProtKB:P35228	509..529
		Flavodoxin_1	535..666	CDD:425562
		FNR_like	730..1126	CDD:447143	113/419 (27%)
CG14882	NP_650544.1	methionine_synthase_red	66..453	CDD:99800	112/412 (27%)