Protein Alignment Nkx2-5 and HGTX

DIOPT Version :9

• Sequence 1: NP_032726.1
• Gene: Nkx2-5 / 18091
• MGIID: 97350
• Length: 318
• Species: Mus musculus
• Sequence 2: NP_001368954.1
• Gene: HGTX / 53446
• FlyBaseID: FBgn0040318
• Length: 587
• Species: Drosophila melanogaster
• Alignment Length: 187
• Identity: 51/187 - (27%)
• Similarity: 86/187 - (45%)
• Gaps: 20/187 - (10%)

Mouse     9 PTPFSVKDILNLEQQQRSLASGDLSARLEATLAPASCMLAAFKPEAYSGPEAAASGLAELRAEMG 73
            |.|..:..||:   :...:.|..|||...|.:...|.             .|||:|:|:..::..
  Fly   358 PNPHGIDTILS---KPPPVTSAGLSALTGAGIPRFSI-------------AAAAAGMAQYLSQSQ 406

Mouse    74 PAPSPPKCSPAFPAAPTFYPGAYGDPDPAKDPRADKKELCALQKAVELDKAETDGAERPRARRRR 138
            .||..............::||..|   ...:|.|.::.|.....| .|.::........:..:::
  Fly   407 GAPLKTHAGHIVDRTHLYWPGLQG---LVANPIAWRERLSNTMSA-NLSQSHQHHPSNDKDGKKK 467

Mouse   139 KPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTSTQVKIWFQNRRYKCKRQ 195
            ..|..||..|::.||:.|:|.:||:.|||.:||..|.::.:|||:||||||.|.:::
  Fly   468 HTRPTFSGQQIFALEKTFEQTKYLAGPERAKLAYALGMSESQVKVWFQNRRTKWRKR 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nkx2-5	NP_032726.1	Homeobox	144..194	CDD:365835	25/49 (51%)
HGTX	NP_001368954.1	ROM1	179..>388	CDD:227709	9/32 (28%)
		Homeobox	469..523	CDD:395001	26/53 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910