Protein Alignment Nkx2-5 and bap

DIOPT Version :10

• Sequence 1: NP_032726.1
• Gene: Nkx2-5 / 18091
• MGIID: 97350
• Length: 318
• Species: Mus musculus
• Sequence 2: NP_732637.1
• Gene: bap / 42537
• FlyBaseID: FBgn0004862
• Length: 382
• Species: Drosophila melanogaster
• Alignment Length: 389
• Identity: 119/389 - (30%)
• Similarity: 155/389 - (39%)
• Gaps: 115/389 - (29%)

Mouse     4 SPALTPTPFSVKDILNLEQ-QQRSLASGDLSARLEATLAPASCMLAAFKPEAYSGPEAAASGLAE 67
            |.:|| ||||:.|||.... :.|.::|.|.....| .|.|:|
  Fly    17 SKSLT-TPFSINDILTRSNPETRRMSSVDSEPEPE-KLKPSS----------------------- 56

Mouse    68 LRAEMGPAPSPPKC------------SPAFPAA--PTFYPGAYG---------------DPDPAK 103
             ..|...:.|||.|            ....|:|  |:.|...|.               ....|.
  Fly    57 -DRERSISKSPPLCCRDLGLYKLTQPKEIQPSARQPSNYLQYYAAAMDNNNHHHQATGTSNSSAA 120

Mouse   104 DPRADKKELCALQKAVELD-------KAETDG--------AERPRAR------RRRKPRVLFSQA 147
            |....|........|..||       .::.|.        :|.|.:.      |:::.|..||.|
  Fly   121 DYMQRKLAYFGSTLAAPLDMRRCTSNDSDCDSPPPLSSSPSESPLSHDGSGLSRKKRSRAAFSHA 185

Mouse   148 QVYELERRFKQQRYLSAPERDQLASVLKLTSTQVKIWFQNRRYKCKR-QRQDQTLELLGPPPPPA 211
            ||:||||||.||||||.|||.::|..|:||.|||||||||||||.|| |.|.....|||    .:
  Fly   186 QVFELERRFAQQRYLSGPERSEMAKSLRLTETQVKIWFQNRRYKTKRKQIQQHEAALLG----AS 246

Mouse   212 RRIAVPVLVR-DGKPCLGDPAAYAPAYGVGLNAYGYNAYPYP---SYGGAACS------PGYSCA 266
            :|:.|.|||| ||.......|  ||..|.||:....|.|.:.   :|||....      |.:
  Fly   247 KRVPVQVLVREDGSTTYAHMA--APGAGHGLDPALINIYRHQLQLAYGGLPLPQMQMPFPYF--- 306

Mouse   267 AYP--AAPPAAQPP--------AASANSNFVNFGV-GDLNTVQSP-GMPQG-----NSGVSTLH 313
             ||  ..|....||        |:||:|:.|...: |.:...::| ..|.|     .||..::|
  Fly   307 -YPQHKVPQPIPPPTQSSSFVTASSASSSPVPIPIPGAVRPQRTPCPSPNGQMMSVESGAESVH 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nkx2-5	NP_032726.1	Homeodomain	144..194	CDD:459649	37/49 (76%)
bap	NP_732637.1	Homeodomain	176..232	CDD:459649	38/55 (69%)