DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Nkx2-5 and bap

DIOPT Version :9

Sequence 1:NP_032726.1 Gene:Nkx2-5 / 18091 MGIID:97350 Length:318 Species:Mus musculus
Sequence 2:NP_732637.1 Gene:bap / 42537 FlyBaseID:FBgn0004862 Length:382 Species:Drosophila melanogaster


Alignment Length:389 Identity:119/389 - (30%)
Similarity:155/389 - (39%) Gaps:115/389 - (29%)


- Green bases have known domain annotations that are detailed below.


Mouse     4 SPALTPTPFSVKDILNLEQ-QQRSLASGDLSARLEATLAPASCMLAAFKPEAYSGPEAAASGLAE 67
            |.:|| ||||:.|||.... :.|.::|.|.....| .|.|:|                       
  Fly    17 SKSLT-TPFSINDILTRSNPETRRMSSVDSEPEPE-KLKPSS----------------------- 56

Mouse    68 LRAEMGPAPSPPKC------------SPAFPAA--PTFYPGAYG---------------DPDPAK 103
             ..|...:.|||.|            ....|:|  |:.|...|.               ....|.
  Fly    57 -DRERSISKSPPLCCRDLGLYKLTQPKEIQPSARQPSNYLQYYAAAMDNNNHHHQATGTSNSSAA 120

Mouse   104 DPRADKKELCALQKAVELD-------KAETDG--------AERPRAR------RRRKPRVLFSQA 147
            |....|........|..||       .::.|.        :|.|.:.      |:::.|..||.|
  Fly   121 DYMQRKLAYFGSTLAAPLDMRRCTSNDSDCDSPPPLSSSPSESPLSHDGSGLSRKKRSRAAFSHA 185

Mouse   148 QVYELERRFKQQRYLSAPERDQLASVLKLTSTQVKIWFQNRRYKCKR-QRQDQTLELLGPPPPPA 211
            ||:||||||.||||||.|||.::|..|:||.|||||||||||||.|| |.|.....|||    .:
  Fly   186 QVFELERRFAQQRYLSGPERSEMAKSLRLTETQVKIWFQNRRYKTKRKQIQQHEAALLG----AS 246

Mouse   212 RRIAVPVLVR-DGKPCLGDPAAYAPAYGVGLNAYGYNAYPYP---SYGGAACS------PGYSCA 266
            :|:.|.|||| ||.......|  ||..|.||:....|.|.:.   :|||....      |.:   
  Fly   247 KRVPVQVLVREDGSTTYAHMA--APGAGHGLDPALINIYRHQLQLAYGGLPLPQMQMPFPYF--- 306

Mouse   267 AYP--AAPPAAQPP--------AASANSNFVNFGV-GDLNTVQSP-GMPQG-----NSGVSTLH 313
             ||  ..|....||        |:||:|:.|...: |.:...::| ..|.|     .||..::|
  Fly   307 -YPQHKVPQPIPPPTQSSSFVTASSASSSPVPIPIPGAVRPQRTPCPSPNGQMMSVESGAESVH 369

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Nkx2-5NP_032726.1 Homeobox 144..194 CDD:365835 37/49 (76%)
bapNP_732637.1 Homeobox 178..231 CDD:278475 38/52 (73%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0842
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.