Protein Alignment Nkx2-5 and NK7.1

DIOPT Version :9

• Sequence 1: NP_032726.1
• Gene: Nkx2-5 / 18091
• MGIID: 97350
• Length: 318
• Species: Mus musculus
• Sequence 2: NP_001247103.1
• Gene: NK7.1 / 41747
• FlyBaseID: FBgn0024321
• Length: 721
• Species: Drosophila melanogaster
• Alignment Length: 363
• Identity: 86/363 - (23%)
• Similarity: 129/363 - (35%)
• Gaps: 100/363 - (27%)

Mouse     9 PTPFSVKDILNLE---------------------------QQQRSLASGDLS---ARLEATLAPA 43
            |||.|:.|||.:.                           |:|:.:.|..:|   |..|.:.|.|
  Fly   190 PTPHSIADILGMSFVKKERPEVAFDAQGPAKSPNSILKPYQEQQPIRSSSISMSDASEEESAAVA 254

Mouse    44 SCMLAAFKPEAYSGPEAAAS----------------------------------GLAELRAEMG- 73
            ....||....|.:....||:                                  |.:..:.|..
  Fly   255 GATSAATAAAAVAATITAATVATPLDQPLNLCVVKKSRDSNNSPMPATKQSQILGKSATKKESSG 319

Mouse    74 -PAPSPPKCSPAFPAAPTFYPGAYGD------------PDPAKDPRADKKELCALQKAVELDKAE 125
             ||....|.|......|...|....|            ..|..:..|..:.  .....:|..:.:
  Fly   320 KPAAKKKKLSSTVALPPDISPTGSSDSLMRDKLMANNSSSPGSNVNAQMQS--NANSTLETTEDD 382

Mouse   126 TDGAERPRARRRRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTSTQVKIWFQNRRY 190
            :|..... |||::|.|..|:..|::|||:.|:.::||||.||.::|.:|.:|.|||||||||||.
  Fly   383 SDSGSTD-ARRKKKARTTFTGRQIFELEKMFENKKYLSASERTEMAKLLMVTETQVKIWFQNRRT 446

Mouse   191 KCKRQRQDQTLELLGPPPPPARRIAVPVLVRDGKPCLGDPAAYAPAYGVGLNAYGYNAYPYPSYG 255
            |.|:|......|            |......:.||.....|...|: |...:....|| ..|:.|
  Fly   447 KWKKQDNVTNNE------------AAEHKSSNAKPGATGTATTTPS-GEPTDKRSSNA-TSPTVG 497

Mouse   256 GAACSPGYSCAAYPAAPPAAQPPAASANSNFVNFGVGD 293
            .||     :.|....:|.:....:.:.|:|.:|..|.:
  Fly   498 NAA-----TIAEIKKSPKSPNRGSNNNNNNTLNNNVNN 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nkx2-5	NP_032726.1	Homeobox	144..194	CDD:365835	27/49 (55%)
NK7.1	NP_001247103.1	Homeobox	397..449	CDD:278475	28/51 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833357
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840