Protein Alignment Nkx2-5 and Antp

DIOPT Version :10

• Sequence 1: NP_032726.1
• Gene: Nkx2-5 / 18091
• MGIID: 97350
• Length: 318
• Species: Mus musculus
• Sequence 2: NP_996167.1
• Gene: Antp / 40835
• FlyBaseID: FBgn0260642
• Length: 378
• Species: Drosophila melanogaster
• Alignment Length: 205
• Identity: 44/205 - (21%)
• Similarity: 72/205 - (35%)
• Gaps: 61/205 - (29%)

Mouse     3 PSPALTPTPFSVKDILNLEQQQRSLASGDLSARLEATLAPASCMLAAFKPEAYSGPEAAASGLAE 67
            |...|..|...|.|:..:.|...::......:.:....||...|
  Fly   204 PQAQLGYTDVGVPDVTEVHQNHHNMGMYQQQSGVPPVGAPPQGM--------------------- 247

Mouse    68 LRAEMGPAPSPPKCSPAFPAAPTFYPGAYGDPDPAKDPRADKKELCALQKAVELDKAETDGAERP 132
                |.....||:.....|...|         .|:::|                 .:::.|...|
  Fly   248 ----MHQGQGPPQMHQGHPGQHT---------PPSQNP-----------------NSQSSGMPSP 282

Mouse   133 ----------RARRRRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTSTQVKIWFQN 187
                      :.:.|::.|..:::.|..|||:.|...|||:...|.::|..|.||..|:||||||
  Fly   283 LYPWMRSQFGKCQERKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQN 347

Mouse   188 RRYKCKRQRQ 197
            ||.|.|::.:
  Fly   348 RRMKWKKENK 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nkx2-5	NP_032726.1	Homeodomain	144..194	CDD:459649	23/49 (47%)
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	20/152 (13%)
		Homeodomain	298..354	CDD:459649	24/55 (44%)