Protein Alignment Nkx2-5 and zen

DIOPT Version :10

• Sequence 1: NP_032726.1
• Gene: Nkx2-5 / 18091
• MGIID: 97350
• Length: 318
• Species: Mus musculus
• Sequence 2: NP_476793.1
• Gene: zen / 40828
• FlyBaseID: FBgn0004053
• Length: 353
• Species: Drosophila melanogaster
• Alignment Length: 189
• Identity: 54/189 - (28%)
• Similarity: 73/189 - (38%)
• Gaps: 36/189 - (19%)

Mouse   138 RKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTSTQVKIWFQNRRYKCKRQRQDQTLE 202
            ::.|..|:..|:.|||..||...||....|.::|..|.|...||||||||||.|.|:..|...
  Fly    91 KRSRTAFTSVQLVELENEFKSNMYLYRTRRIEIAQRLSLCERQVKIWFQNRRMKFKKDIQGHR-- 153

Mouse   203 LLGPPPPPARRIAVPVLVRDGKPCLGDPAAYAPAY-GVGLNAYGYNAYPYPSYGGAACSPGYSCA 266
               .|...|:              |..|.|...|: |:......|:  ..|..|.||.......|
  Fly   154 ---EPKSNAK--------------LAQPQAEQSAHRGIVKRLMSYS--QDPREGTAAAEKRPMMA 199

Mouse   267 AYPAAP----PAAQPPAASANSNFVNFGVGDLNTV-----QSPGMPQ-----GNSGVST 311
            ..|..|    .|:|.....|::|.......||:.:     |:...||     .::|.||
  Fly   200 VAPVNPKPDYQASQKMKTEASTNNGMCSSADLSEILEHLAQTTAAPQVSTATSSTGTST 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nkx2-5	NP_032726.1	Homeodomain	144..194	CDD:459649	24/49 (49%)
zen	NP_476793.1	Homeodomain	91..147	CDD:459649	25/55 (45%)