Protein Alignment Nkx2-5 and scro

DIOPT Version :9

• Sequence 1: NP_032726.1
• Gene: Nkx2-5 / 18091
• MGIID: 97350
• Length: 318
• Species: Mus musculus
• Sequence 2: NP_001015473.1
• Gene: scro / 3355151
• FlyBaseID: FBgn0287186
• Length: 468
• Species: Drosophila melanogaster
• Alignment Length: 373
• Identity: 122/373 - (32%)
• Similarity: 163/373 - (43%)
• Gaps: 82/373 - (21%)

Mouse    10 TPFSVKDILN-LEQQQRSLASGDLSARLEATLAPASCMLAAFKPEAYSGPEAAASGLAELRAEMG 73
            |||||.|||: :|:..|         :||....|.|...:.....:.:.|....:........||
  Fly   114 TPFSVTDILSPIEESYR---------KLELNGNPPSPFRSNSSSSSINSPGTLTTSTMANPYAMG 169

Mouse    74 PAPSPP----KCSPAFPAAPTFYPGAYGD--------PDPAKDPRADKKELCA------------ 114
            .....|    .|.|....:   ..|.|.|        ...|.|||.....|.:
  Fly   170 TLYHSPGVQTYCGPTDNLS---LAGHYTDMRNSASWYGSTANDPRFAISRLMSSSASGTMSHMGN 231

Mouse   115 LQKAVELDKAETDGAERPRARRRRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTST 179
            :........:::...:.|.|:||:: ||||:||||||||||||||||||||||:.|||::.||.|
  Fly   232 MSGLAACSVSDSKPLQFPLAQRRKR-RVLFTQAQVYELERRFKQQRYLSAPEREHLASLIHLTPT 295

Mouse   180 QVKIWFQNRRYKCKRQRQDQTLELLGPPPPPA---RRIAVPVLVRDGKPCLG-DPAAYAPAYGVG 240
            ||||||||.|||||||.:::.:........||   ||:||||||:|||||.| :.::.:..:|..
  Fly   296 QVKIWFQNHRYKCKRQAKEKAMAEQNQHNQPASSPRRVAVPVLVKDGKPCSGNNSSSQSQQHGTN 360

Mouse   241 LNAYGYNAYPYPSYGGAACSPGYSCAAYPA---------APPAAQPPAASANSNFVNFG-VGDLN 295
            ..:.|.|.  ..:..|.|.|...|..|..:         ||.:..|..:|  |...::| ||..|
  Fly   361 STSAGNNT--GSANNGNANSGIVSVTANVSGGLNLITGDAPNSHSPDTSS--SLLASYGTVGGSN 421

Mouse   296 T--VQSP-----------------------GMPQGNSGVSTLHGIRAW 318
            .  :|.|                       |..|...|...|.| |||
  Fly   422 VAMLQQPCNNTLMSNSLAMAYRNQNNFISNGHQQQCGGYLPLQG-RAW 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nkx2-5	NP_032726.1	Homeobox	144..194	CDD:365835	41/49 (84%)
scro	NP_001015473.1	Homeobox	256..309	CDD:278475	43/53 (81%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833348
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0842
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740