Protein Alignment DPYSL2 and CG6106

DIOPT Version :9

• Sequence 1: NP_001184222.1
• Gene: DPYSL2 / 1808
• HGNCID: 3014
• Length: 677
• Species: Homo sapiens
• Sequence 2: NP_001285403.1
• Gene: CG6106 / 32816
• FlyBaseID: FBgn0030914
• Length: 486
• Species: Drosophila melanogaster
• Alignment Length: 520
• Identity: 128/520 - (24%)
• Similarity: 199/520 - (38%)
• Gaps: 127/520 - (24%)

Human   115 INDQSDRLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPGGVKT----IEAHS------RM 169
            :.|.|...||.||.||:           .:|:|:::   |..|..|.|    .|:.|      .:
  Fly    12 LGDGSQNALIHGGIIVD-----------TEGIIRRV---LRSPQEVNTYLYNTESESVYDFGDLV 62

Human   170 VIPGGIDVHTRFQMPDQGMTSADDFFQGTKAALAGGTTMIIDHVV-PEPGTSLLAAFDQWREWAD 233
            ::||.||.:.....|  |....:.|...||||.|||.|.|||... .:|.|..:|........|.
  Fly    63 LMPGLIDPNVHINEP--GRKDWEGFATATKAAAAGGFTTIIDRPTNAQPPTVSVAHLKAKTSTAR 125

Human   234 SKSCCDYSLHVDISEWH---KGIQEEMEALVKDHGVNSFLVYMAFKDRFQLTDC----------- 284
            .|      ::||:..|.   .|..:::.||: ..||..          .|.|.|
  Fly   126 GK------IYVDVGFWGGLVPGNGDQLAALL-GAGVMG----------LQCTLCDPAAPVSQEFP 173

Human   285 -----QIYEVLSVI-RDIG---AIAQVHAE---NGDIIAEEQQRILDLGITGPEGH---VLSRPE 334
                 |:.|.||.: :|..   ||..||||   ..:|..:|:         .|..:   :::||.
  Fly   174 AVNESQLEEALSQLDKDQAEGEAIVAVHAELPLTTEIHPDEE---------APREYGTFLVTRPP 229

Human   335 EVEAEAVNRAITIANQ--TNCPLYITKVMSKSSAEVIAQARKKGTVVYGEPITASLGTDG-SHYW 396
            ::|..|......:||:  ..| ::|....|..|..::.:.|::|         .:|..|. .||
  Fly   230 QMEISATQLLCRLANRHPRRC-IHILNCSSGESLPLVEECRRQG---------GNLTVDTCPHY- 283

Human   397 SKNWAKAA--------AFVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAV----G 449
               .|.||        .|.|.||:...........:|...|.:::.||.|.......:|:    |
  Fly   284 ---LALAAEDVPDCGTEFKTWPPIRERRNQEQLWQALRPGGAIRMIGSDHSPATPGARALTCGRG 345

Human   450 KDNFTLIPEGTNGTEERMSVIWDKAVVTGKMDENQFVA----VTSTNAAKVFNLYPRKGRIAVGS 510
            :.||.....|.|..:..:||:| .|....:...|..:|    :.....|.:..|...|||||.|.
  Fly   346 RGNFLKAWPGINSLQLSLSVVW-TAAANRRGSANLTIADIHRLMCQEPANLCGLSASKGRIAEGY 409

Human   511 DADLVIWDPDSVKTISAKTHNSSLEYNIFEGMECRGSPLVVISQGKIVLEDGTLHV---TEGSGR 572
            |||..:|.|:...|:..:...::.:...:.|.:.||.....:.:|        |||   .||.|:
  Fly   410 DADFCVWSPEEEFTVGPELLYTATKATPYAGQKLRGVVHATVVRG--------LHVYQQFEGFGQ 466

Human   573  572
              Fly   467  466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DPYSL2	NP_001184222.1	D-HYD	122..571	CDD:238639	125/510 (25%)
CG6106	NP_001285403.1	L-HYD_ALN	2..473	CDD:238640	128/520 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0044
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D719800at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820