Protein Alignment vit-2 and cv-d

DIOPT Version :9

• Sequence 1: NP_508868.1
• Gene: vit-2 / 180781
• WormBaseID: WBGene00006926
• Length: 1613
• Species: Caenorhabditis elegans
• Sequence 2: NP_732076.1
• Gene: cv-d / 41921
• FlyBaseID: FBgn0265048
• Length: 1470
• Species: Drosophila melanogaster
• Alignment Length: 1624
• Identity: 313/1624 - (19%)
• Similarity: 614/1624 - (37%)
• Gaps: 396/1624 - (24%)

 Worm    32 YKFDGLVLSG---------LPSASSELSQSRISARARIQAVDDRYIHLQLVNIRMAASHLPESEQ 87
            |:::|.||.|         .|..:..:.:.:::.:.:.:.|             :||:.:.:.
  Fly    33 YEYEGNVLVGAKPQDEGHQAPPTTGWIVRGKLTLQRQSELV-------------LAAALVIDD-- 82

 Worm    88 MPSLNS-----MEQRELSEEYKQMLELPLRAQL-RNGLISELQFDKEDAEWSKNMKRAVVNMISF 146
             .:||:     ::.:|:...||     |.:..| ::|.||.:.|.:.|..||.|.|||:.:::.|
  Fly    83 -VTLNNSGEKFLQNKEMYPPYK-----PFKIALTKDGAISHVVFKEGDPIWSMNFKRAIASVLQF 141

 Worm   147 NPIAPRNEIEKIESSYDKEEQSEENTSFFTNEKTLEGDCQVAYTVIREQKKTIITKSINFDKCTE 211
                                |.:.:.:|..:|..:.|.|:..|.|........|.|:.....|..
  Fly   142 --------------------QMKSSGAFVVDELGIHGTCRTEYFVSNRTNYISIRKTPEVKTCKP 186

 Worm   212 RSEIAYGLRYSSECPECEKDTE---LIRPQTVYTYVLENEELKESEVRSLYTVNVNGQEVMKTET 273
            .||..:..|.:.....||.|.:   :|..:.:|.....||               .|..:.....
  Fly   187 YSEAVHTTRSNVPPNTCEFDHQKSVIIGNEAIYGMSPHNE---------------TGYYLSMAHA 236

 Worm   274 RSKLVLEENHSIKSHIKKVNGEKESIIYSSRWEQLVEDFFKNGDKAEFAPFEKFPLDKKMHLIKT 338
            :...::   |:.:|     .||.:.|.     .:|:.:|           ..:.|:|..:.:..:
  Fly   237 KGTTLI---HTFES-----TGEAQFIN-----SELLLNF-----------LNETPIDNPIDIETS 277

 Worm   339 ITE-----QIQEVENNMP---------------------------ETSHFLARLVRIFRTTSTSQ 371
            :..     ::|.::.|.|                           ||:.|  :....:.:|.:..
  Fly   278 MAAEPSNLELQRLDPNDPTGGRSPQQQETLIAQAGTLLDSLAEALETTEF--KFSEPYDSTLSDV 340

 Worm   372 LKEIHE-------TLYVKAD-------KKIQSLMEHALAIAGTKNTI---QHILVHMENEDILPL 419
            :|.:.|       .||.:.|       :.|:::....:...|||.::   .|::::.     |..
  Fly   341 IKLLSEMDFDSLTKLYREVDIGTSYRQETIRNIFHEIIPRIGTKASVFLTHHLVLNK-----LTK 400

 Worm   420 GQI-LKTIQETPFPSQSIAEALIKFAES--RVAKNNLVVRQAAWLAAGSVVRGIVDYKNIRPLVR 481
            .|| ::.:...||....::..|::..|.  .:..:...|||||.|:..:::..:...|.|
  Fly   401 PQIAVQLLIPMPFHIFELSAELVQKCEDFLNIGPDRPDVRQAAILSFATLIHNVYVAKGI----- 460

 Worm   482 EDKRELKEKFLRVFMQQYKDAETTYEKILALKTIGNAGLDISVNQLNEIIVDKRQPLPVRKEAID 546
             ||.:. |::::.:...|.......:|:|.|:.:.|..|....|.|..|:.|..:...::.:|..
  Fly   461 -DKEKF-EEYVQKYFNAYLSDRDFDQKMLYLQGLNNLQLGNVANYLEPIVQDPNEHEDLKFQAAW 523

 Worm   547 ALRLLKDTMPRKIQKVLLPIYKNRQYEPEIRMLALWRMMHTRPEESLLVQVVSQMEKETNQQVAA 611
            ....|.|....:|.:|..||:::|....|:|:.|:..::.:.|..:.|:.:...::.||:..:..
  Fly   524 TTLALADRRAERIYEVYWPIFESRNASLELRVAAVTLLLISNPTAARLISIHRIIQSETDPHMIN 588

 Worm   612 LTHQMIRHFAMSTNPCYQRVAIVCSKVLSFT-RYQPQE----QMIASSYAQLPLFLQNSFSGAQF 671
            .....:...:.:|.||||.:    .::||:. |:.||:    ..:..:|    :|   .:..::|
  Fly   589 YYRTTVTSISETTYPCYQHL----RRLLSYMHRHLPQKPESRYWVTGNY----IF---DYRDSKF 642

 Worm   672 DFAAIFEKNSFLPKDLHASLDAVFGGNWNKYFAQIGFSQQHMDKYV-QMALEKLESLEKESTTVV 735
            ...|:.:  .||..|..:.:..|         |...|..:.:.|:. |:||            .:
  Fly   643 GIGAMLQ--VFLVGDPKSDMPVV---------AFFKFDTEALGKFTGQLAL------------YI 684

 Worm   736 RGRRIQTGIKLLKELAQKMNIRARPATYTEKDAFAMV------YLRYKDMDYAFLPIDRQLVENL 794
            :.|.:...|      ..||..|.....:|.|...|::      .:..||:...|:   .|:....
  Fly   685 KARGLPDTI------LNKMQSRNGSDPFTFKSIKALLAMLQAPIINSKDLHLEFI---LQMEGKT 740

 Worm   795 IEKFTSNGK----VQFSEIRRLLNQELEFETHHAAYFYEAIR-------KFPTTLGLPLTISGKI 848
            :..:..|.:    :.:..|...:.|.:..::|   ...:.:|       ..||.||....:..:.
  Fly   741 VLSYYLNQRMFRQLTYDNILERMQQIIRTDSH---INMQTVRWPFMNRYTVPTVLGTSSDVLLQT 802

 Worm   849 PTVISAEGQFSLELEG--TELRLTVEARPSVAATHVYEMRMFTPL--FEQGVKSVQSVRAYTPIK 909
            ..:.|..|..:.:...  |:..|.::||.|..|:  ...|.:.|.  .:..:...|....|.|..
  Fly   803 TVLTSLRGNITEQRNSPITKHTLEIDARYSSYAS--VRSRSYNPFLNLDHEINREQGFLIYIPFS 865

 Worm   910 IQA---VAGMK-RNFEIVYKVVVPENQKSIVSLTTRPVVFLRFPG-FSKFEYIEAEERTVVVPQW 969
            .:.   .:|.| |.    |....|:|..|.:|..:|.|...|  | .:|......||  ::||:.
  Fly   866 SELHLNESGSKCRR----YSFSRPQNLTSGLSFKSRAVTKTR--GLITKTAAAPFEE--IMVPEG 922

 Worm   970 QQKTQEIEKVFNF----LGLEVSTRGNILNQHTLENWLLAEQDFEVSVENKNRPAEFTARLTVGQ 1030
            :   .::.::|::    ||:.:|...| ||:......:|.:.:|   .||     .|:..:.|..
  Fly   923 R---NDVVQLFSYPMTDLGVRLSMTTN-LNELIKYRGMLLKSEF---TEN-----GFSGNMVVNA 975

 Worm  1031 LEK----TELSQIKYNKIFEKEFELEQENTESRREYFNKMVKNIQKEQGYK-SVISLKLE----- 1085
            |..    |:||.|...  .::.|.:...|.::.|...|...:::.|....| ..|.|.||
  Fly   976 LMYIFGFTQLSSIHLG--HDRNFTMLMYNEKNTRIEGNFCAEDVLKTSDMKGKQIGLTLEHTDHM 1038

 Worm  1086 -----APRDYTMNTELTTVCDKQVRMCQWEVEIRRSPILEETKEWTLRSQLL---VVRPEMPSSL 1142
                 |...:..|..|..:...:....:...:::|:. .::..:|...::|.   :|..:.|.:|
  Fly  1039 NENHAADALHRWNITLDVLASTKSNWFKLTGQVQRNS-KDDEDDWKACTKLTYEPLVFTKRPHTL 1102

 Worm  1143 RQLRDQPHREVQLSLTSTWGS--QKKSEVTVNAQLQQSKEQKKYERNMDR--------------Q 1191
                   :.:|...|.:....  :|.|.|...|:...|:..:.:.|: |:              :
  Fly  1103 -------NGDVVFGLATEESECPEKGSTVQFAARAGPSEHARAFLRS-DKISLTDTDFCPKEVLK 1159

 Worm  1192 FNGMPEYELLIKAARLNQINAVAEYKLTRETEQVLARYFDLVKTYNYWTVSSRPENNENDRVVVQ 1256
            |:.:|. ....|.:......::.:|.:..:.:.:.| :|:|      |       :|..|.:|..
  Fly  1160 FSPIPT-SRYCKRSNFENFTSITQYDMDLKFDNMPA-WFEL------W-------SNRLDHLVSA 1209

 Worm  1257 LTVEPMS----RQYVNITMQSPMER----IELKNV-----QVPRVY-LPSIAQRSVKHQLTEASG 1307
            |:.:.:.    .|.:||:||:|.::    :|:..|     |:|..| |.|  :....|:||..||
  Fly  1210 LSADKVDSLHMSQEINISMQTPQDQFRLAVEVNGVKWRFHQIPFFYKLDS--KFDASHELTFDSG 1272

 Worm  1308 --SVCKVQKNQIRTFDDVLYN----TPLTTCYSLIAKDCSEEPTFAV------------------ 1348
              ..|.|....:.||||.|.|    .....|.:|:..|||..|..||
  Fly  1273 LKRSCSVINGIVNTFDDYLINLREIAVRPDCLTLLVADCSPLPQIAVFVTPSPVQGLSTNYGLRV 1337

 Worm  1349 --------LSKKTEKNS---EEMIIKVIRGEQEIVAQLQNEEIRVKVDGKKIQSEDYSAYQIERL 1402
                    ...:|:.:|   :|.::..:..:|      ....:|.|.....|::.||. :::|..
  Fly  1338 HIGQNYFNFRARTDNSSLPTDEPVLIYLNQDQ------TPHNVRKKPYQWPIETSDYD-FRVELN 1395

 Worm  1403 GESAIVIELPE--GEVRFDGYTIKTQLPSYS-RKNQLCGLCGNNDDESTNEFYT----SDNTET 1459
            .::.:::|..:  ..::||.|.| .....|. .|:|:||||....:...|  ||    ..||.|
  Fly  1396 EQNILIVECTQLSSTIQFDLYNI-LNFEIYGVYKHQMCGLCSKPLNRMQN--YTICELEANTPT 1456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vit-2	NP_508868.1	Vitellogenin_N	24..618	CDD:279663	118/655 (18%)
		DUF1943	653..944	CDD:286281	57/316 (18%)
		VWD	1299..1456	CDD:214566	46/198 (23%)
cv-d	NP_732076.1	LPD_N	28..589	CDD:214755	118/649 (18%)
		DUF1943	632..>813	CDD:286281	37/222 (17%)
		VWD	1277..1435	CDD:295339	36/165 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159767
Domainoid	1	1.000	75	1.000	Domainoid score	I5894
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	128	1.000	Inparanoid score	I3236
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D25081at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14451
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23345
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.000