DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment T07F12.2 and znrf3

DIOPT Version :9

Sequence 1:	NP_508831.3	Gene:	T07F12.2 / 180762	WormBaseID:	WBGene00020322	Length:	289	Species:	Caenorhabditis elegans
Sequence 2:	NP_001295484.1	Gene:	znrf3 / 556813	ZFINID:	ZDB-GENE-070705-263	Length:	866	Species:	Danio rerio

Alignment Length:	159	Identity:	41/159 - (25%)
Similarity:	65/159 - (40%)	Gaps:	33/159 - (20%)

- Green bases have known domain annotations that are detailed below.

Worm    90 WLLFSFLLIIQVAYAKIPREYEEVENQDNMLFTVTEPYTLAYTYQMKHAFMLGVHFPDGANKTFR 154
            |:|.| :|....|:.::.. :|...|.|         || .||..::..|...     ||..:..
Zfish    22 WVLGS-VLAKDTAFVEVVL-FESSPNGD---------YT-TYTTGLQGRFSRA-----GATISAE 69

Worm   155 NLEMVLADPVHGC----EALRNEIFAPSVILMERGECS---FTV--KALNGEKAGATVIMVTDSQ 210
            . |:|...|:..|    |....|.....|:.:|:.|..   .||  ||....:.|||.::...|:
Zfish    70 G-EIVQMHPLGLCNNNDEEDLYEYGWVGVVKLEQPELDPSCLTVLGKAKRAVQRGATAVIFDVSE 133

Worm   211 NYEYSYHQYYVNMIPDESLDRANVPCVYV 239
            |.: :..|  :|.:.::.|.|   |.|||
Zfish   134 NPD-AIDQ--LNQVSEDPLKR---PVVYV 156

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
T07F12.2	NP_508831.3	Peptidases_S8_S53	140..263	CDD:299169	28/109 (26%)
znrf3	NP_001295484.1	zf-RING_2	265..306	CDD:290367
znrf3	NP_001295484.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	790..811
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910