DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment F13C5.2 and tbrd-3

DIOPT Version :9

Sequence 1:	NP_508124.1	Gene:	F13C5.2 / 180410	WormBaseID:	WBGene00017423	Length:	374	Species:	Caenorhabditis elegans
Sequence 2:	NP_726307.1	Gene:	tbrd-3 / 246604	FlyBaseID:	FBgn0050417	Length:	268	Species:	Drosophila melanogaster

Alignment Length:	227	Identity:	63/227 - (27%)
Similarity:	101/227 - (44%)	Gaps:	33/227 - (14%)

- Green bases have known domain annotations that are detailed below.

Worm   102 AKSESEDEAESDHLHDELKKCLSILKEFEKSTHDSFTFPFRKPVDVVLLGLTDYHEVIKKPMDMS 166
            ||.|:|..:      .|:..|..|:|....||:.:..:.|.:|:|..||||.||||::::|||:|
  Fly     3 AKQETERSS------PEINACKVIIKRLFSSTYKNIAWVFYEPLDPQLLGLHDYHEIVREPMDLS 61

Worm   167 TIRKKLIGEEYDTAVEFKEDFKLMINNCLTYNNEGDPVADFALQFRKKFAAKWKKEFPEDGDSFG 231
            |:|.:|....|.:|.:|.:|.:|:..|...|.|........|.|.:..|     :|.......:.
  Fly    62 TVRHRLNTGCYLSAADFAKDIRLIFYNTYLYTNPDHLCYHMAKQLQIIF-----EEMYSQVQLYI 121

Worm   232 QEKGEKEGSDNEDDEEEVDEKEKEEEVKEDNAEEKPA---EEPEQPDEKEEEDHED-------ER 286
            ...|.|..::.|...:|.|....|:||  :.:|..|:   ..|......|.....|       |.
  Fly   122 CSSGSKVRAEEESSSDESDSSSPEDEV--NGSEVSPSIMGAPPSCTPTTECTPTPDWTPPATLET 184

Worm   287 EEQEEEDSSDEEDGLD--------DDDVRRHI 310
            .||:|..:::|:  ||        |.:|..|:
  Fly   185 SEQQEPFTTEED--LDLHAKIQQLDGEVLLHV 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
F13C5.2	NP_508124.1	Bromodomain	118..219	CDD:383021	35/100 (35%)
tbrd-3	NP_726307.1	Bromo_Brdt_II_like	13..114	CDD:99930	36/105 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166227
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	80	1.000	Inparanoid score	I3803
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000322
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22880
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X197
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.890