| Sequence 1: | NP_035022.2 | Gene: | Nek2 / 18005 | MGIID: | 109359 | Length: | 443 | Species: | Mus musculus |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_651293.1 | Gene: | niki / 42959 | FlyBaseID: | FBgn0045980 | Length: | 841 | Species: | Drosophila melanogaster |
| Alignment Length: | 520 | Identity: | 147/520 - (28%) |
|---|---|---|---|
| Similarity: | 233/520 - (44%) | Gaps: | 131/520 - (25%) |
- Green bases have known domain annotations that are detailed below.
|
Mouse 1 MPSRVE---------------------DYEVLHSIGTGSYGRCQKIRRKSDGKILVWKELDYGSM 44
Mouse 45 TEVEKQMLVSEVNLLRELKHPNIVSYYDRIIDRTNTTLYIVMEYCEGGDLASVISKGTKDRQYLE 109
Mouse 110 EEFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFLDSKHNVKLGDFGLARILN---HDTS 171
Mouse 172 FAKTFVGTPYYMSPEQMSCLSYNEKSDIWSLGCLLYELCALMPPFTAFNQKELAGKIREGRFRRI 236
Mouse 237 PYRYSDGLNDLITRMLNLKDYHRPSVEEILE--SPLIADLVAEEQRRNLERRGRRSGE-----PS 294
Mouse 295 KLPDSSPVLSELKLKERQLQDREQAL---RAREDILEQKERELCIRERLAEDKLARAESLMKNYS 356
Mouse 357 LLKEHRLL--CLAGGPELDLPSSAMKKKV-----HF----------------HGES--------K 390
Mouse 391 ENTARSENSESYLAKSKC---------------------------RDLKKRLHAAQLRAQALADI 428
Mouse 429 428 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Nek2 | NP_035022.2 | STKc_Nek2 | 7..271 | CDD:270857 | 103/268 (38%) |
| S_TKc | 8..271 | CDD:214567 | 103/267 (39%) | ||
| Interaction with PCNT. /evidence=ECO:0000250 | 264..443 | 43/233 (18%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 282..303 | 4/25 (16%) | |||
| Interaction with CEP85. /evidence=ECO:0000250|UniProtKB:P51955 | 301..443 | 34/189 (18%) | |||
| Leucine-zipper | 306..334 | 7/30 (23%) | |||
| Necessary for interaction with MAD1L1. /evidence=ECO:0000250 | 329..443 | 25/158 (16%) | |||
| Required for microtubule binding and for localization to the centrosomes. /evidence=ECO:0000250 | 333..370 | 3/38 (8%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 383..402 | 8/47 (17%) | |||
| Interaction with SAV1 and STK3/MST2. /evidence=ECO:0000250 | 402..437 | 10/54 (19%) | |||
| niki | NP_651293.1 | STKc_Nek | 104..359 | CDD:270855 | 102/266 (38%) |
| S_TKc | 105..354 | CDD:214567 | 101/260 (39%) | ||
| ATS1 | 445..747 | CDD:227511 | 22/115 (19%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 1 | 1.000 | - | - | FOG0000168 | |
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R445 |
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 4 | 3.940 | |||||