| Sequence 1: | NP_035022.2 | Gene: | Nek2 / 18005 | MGIID: | 109359 | Length: | 443 | Species: | Mus musculus |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_572415.1 | Gene: | Nek2 / 31696 | FlyBaseID: | FBgn0029970 | Length: | 735 | Species: | Drosophila melanogaster |
| Alignment Length: | 492 | Identity: | 177/492 - (35%) |
|---|---|---|---|
| Similarity: | 258/492 - (52%) | Gaps: | 82/492 - (16%) |
- Green bases have known domain annotations that are detailed below.
|
Mouse 5 VEDYEVLHSIGTGSYGRCQKIRRKSDGKILVWKELDYGSMTEVEKQMLVSEVNLLRELKHPNIVS 69
Mouse 70 YYDRIIDRTNTTLYIVMEYCEGGDLASVISKGTKDRQYLEEEFVLRVMTQLTLALKECHRRSDGG 134
Mouse 135 HTVLHRDLKPANVFLDSKHNVKLGDFGLARILNHDTSFAKTFVGTPYYMSPEQMSCLSYNEKSDI 199
Mouse 200 WSLGCLLYELCALMPPF--TAFNQKELAGKIREGRFRRIPYRYSDGLNDLITRMLNLKDYHRPSV 262
Mouse 263 EEILESPLIADLVAE-------------------------------------------EQRRNLE 284
Mouse 285 RRGRRSGEPSKL--PDSSPVLSEL---------KLKERQLQDRE--QALRAREDILEQKERELCI 336
Mouse 337 RERLAEDKLARAESLMKNYSLLKEHRLLCLAGGPELDLPSSAMKKKVHFHGESKENTARSENSES 401
Mouse 402 YLAKSKCRDLKKRLHAAQLRAQALADIEKNYQLKSRQ 438 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Nek2 | NP_035022.2 | STKc_Nek2 | 7..271 | CDD:270857 | 133/265 (50%) |
| S_TKc | 8..271 | CDD:214567 | 132/264 (50%) | ||
| Interaction with PCNT. /evidence=ECO:0000250 | 264..443 | 46/231 (20%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 282..303 | 5/22 (23%) | |||
| Interaction with CEP85. /evidence=ECO:0000250|UniProtKB:P51955 | 301..443 | 35/149 (23%) | |||
| Leucine-zipper | 306..334 | 9/38 (24%) | |||
| Necessary for interaction with MAD1L1. /evidence=ECO:0000250 | 329..443 | 24/110 (22%) | |||
| Required for microtubule binding and for localization to the centrosomes. /evidence=ECO:0000250 | 333..370 | 9/36 (25%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 383..402 | 1/18 (6%) | |||
| Interaction with SAV1 and STK3/MST2. /evidence=ECO:0000250 | 402..437 | 10/34 (29%) | |||
| Nek2 | NP_572415.1 | STKc_Nek2 | 18..281 | CDD:270857 | 132/264 (50%) |
| S_TKc | 19..281 | CDD:214567 | 131/263 (50%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 274 | 1.000 | Domainoid score | I1755 |
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 1 | 1.000 | - | - | FOG0000168 | |
| OrthoInspector | 1 | 1.000 | - | - | oto95196 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_104455 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR43671 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R445 |
| SonicParanoid | 1 | 1.000 | - | - | X4876 | |
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 1 | 0.960 | - | - | ||
| 10 | 9.900 | |||||