Protein Alignment DPEP1 and CG6154

DIOPT Version :10

• Sequence 1: NP_004404.1
• Gene: DPEP1 / 1800
• HGNCID: 3002
• Length: 411
• Species: Homo sapiens
• Sequence 2: NP_651471.2
• Gene: CG6154 / 43184
• FlyBaseID: FBgn0039420
• Length: 434
• Species: Drosophila melanogaster
• Alignment Length: 377
• Identity: 186/377 - (49%)
• Similarity: 249/377 - (66%)
• Gaps: 15/377 - (3%)

Human    17 DFFRDEAERIMRDSPVIDGHNDLPWQLLDMFNNRLQD--------ERANLTTLAGTHTNIPKLRA 73
            ||.......::::.|:|||||||||.:.....|:|:|        |.|..::.|.:||::.:|:.
  Fly    52 DFRMQRVRNVLKEVPLIDGHNDLPWNIRKFLKNQLKDFHFGGDLRELAPWSSSAWSHTDLRRLKE 116

Human    74 GFVGGQFWSVYTPCDTQNKDAVRRTLEQMDVVHRMCRMYPETFLYVTSSAGIRQAFREGKVASLI 138
            |.|..||||.|.||.:|:.|||:.||||:|::.|:.::||.....||:::||.|..|.||:||||
  Fly   117 GMVSAQFWSAYAPCSSQHLDAVQLTLEQIDLIRRLVQLYPHHMALVTTASGIEQTHRTGKIASLI 181

Human   139 GVEGGHSIDSSLGVLRALYQLGMRYLTLTHSCNTPWADNWLVDTGDSEPQSQGLSPFGQRVVKEL 203
            ||||||:|.:||.|||..||||.|||||||:|||||||...||.....|...|||.||:.||||:
  Fly   182 GVEGGHAIGTSLSVLRMFYQLGARYLTLTHTCNTPWADCCKVDEPGKYPHIGGLSQFGKLVVKEM 246

Human   204 NRLGVLIDLAHVSVATMKATLQLSRAPVIFSHSSAYSVCASRRNVPDDVLRLVKQTDSLVMVNFY 268
            ||||:::||:||||.||...|..||||:|||||||:::|.|.|||||.||:.:.....||||.||
  Fly   247 NRLGMIVDLSHVSVPTMLDALAASRAPLIFSHSSAHAICNSSRNVPDHVLQRIAINGGLVMVAFY 311

Human   269 NNYISCTNKANLSQVADHLDHIKEVAGARAVGFGGDFDGVPRVPEGLEDVSKYPDLIAELLRRN- 332
            .:::||:.:|.|..|..|::||:||||...||.|..:|||..||:|||||||||.|.|.||..:
  Fly   312 PHFVSCSGQATLHDVVAHINHIREVAGIDHVGIGAGYDGVNLVPKGLEDVSKYPHLFAALLESDK 376

Human   333 WTEAEVKGALADNLLRVFEAVE----QASNLTQAPEEEPIPLDQLGGS--CR 378
            |:|.::......||:|||:.||    |...|..||.::.||.:.:.|.  ||
  Fly   377 WSEEDIAKLAGRNLIRVFKEVEAVRDQMELLRVAPIDQSIPAEDIMGRSYCR 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DPEP1	NP_004404.1	Peptidase_M19	26..352	CDD:395996	173/334 (52%)
CG6154	NP_651471.2	Peptidase_M19	61..396	CDD:395996	173/334 (52%)