Protein Alignment DPEP1 and CG5282

DIOPT Version :10

• Sequence 1: NP_004404.1
• Gene: DPEP1 / 1800
• HGNCID: 3002
• Length: 411
• Species: Homo sapiens
• Sequence 2: NP_649221.1
• Gene: CG5282 / 40256
• FlyBaseID: FBgn0036986
• Length: 451
• Species: Drosophila melanogaster
• Alignment Length: 368
• Identity: 105/368 - (28%)
• Similarity: 192/368 - (52%)
• Gaps: 56/368 - (15%)

Human    25 RIMRDSPVIDGHNDLPWQLLDMFNNRLQDERANLTTLAGTHTNIPKLRAGFVGGQFWSVYTPCDT 89
            |::.:||:|:|....|                  :|::...:|:.::|...:|...|.:..||..
  Fly   122 RLLTESPLIEGSWKPP------------------STMSLNSSNLFEVRQNHIGAVLWPIAVPCGA 168

Human    90 QNKDAVRRTLEQMDVVHRMCRMYPETFLYVTSSAGIRQAFREGKVASLIGVEGGHSIDSSLGVLR 154
            |..|||:.|||.:|...|:... .::...|.|:..:.|....|:||.|:|:.|||::.:|..|||
  Fly   169 QYLDAVQLTLEGIDRAKRITAA-TDSMHIVESADEMEQTHIRGEVAVLMGISGGHALGTSTAVLR 232

Human   155 ALYQLGMRYLTLTH-SCNTPWA------DNWLVDTGDSEPQSQGLSPFGQRVVKELNRLGVLIDL 212
            ::|.||.|::::|. .|.||||      .::||:    |..:...:.|||.::.|:||||:|:::
  Fly   233 SIYLLGARFVSITSLECTTPWAAAAIRRPDYLVE----ENVTNSFNEFGQTMLFEMNRLGMLVEI 293

Human   213 AHVSVATMKATLQLSRAPVIFSHSSAYSVCASRR--NVPDDVLRLVKQTDSLVMVNFYNNYISCT 275
            :.:|.|.|.|.|:.::|||:.::::..|:|.|..  ::||.||.|:.:...::::|...    |.
  Fly   294 SMLSEAAMLAVLKTAKAPVLLTNATPLSMCNSSNIASIPDHVLSLLPENGGVILLNLER----CG 354

Human   276 NKA-NLSQVADHLDHIKEVAGARAVGFGGDFDGVPRVPEGLEDVSKYPDLIAELLR-RNWTEAEV 338
            ::. .:.:....::::::|||...:|.|    |.|:         .|..|:|||.| |.|..|.:
  Fly   355 DRTLGVREAITAINYVRKVAGVDHIGLG----GAPK---------SYALLLAELARDRVWGNAAI 406

Human   339 KGALADNLLRVFEAVEQASNLTQAP-EEEPIPLDQLGGS--CR 378
            |..:..|::|:...:|...|  :.| .||.||.:.:..:  ||
  Fly   407 KKLVGGNVMRILREIETLKN--RLPLYEEWIPHESIESNSYCR 447

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DPEP1	NP_004404.1	Peptidase_M19	26..352	CDD:395996	95/336 (28%)
CG5282	NP_649221.1	Peptidase_M19	123..420	CDD:395996	95/336 (28%)