Protein Alignment DPEP1 and CG42750

DIOPT Version :10

• Sequence 1: NP_004404.1
• Gene: DPEP1 / 1800
• HGNCID: 3002
• Length: 411
• Species: Homo sapiens
• Sequence 2: NP_724101.4
• Gene: CG42750 / 35090
• FlyBaseID: FBgn0261804
• Length: 1068
• Species: Drosophila melanogaster
• Alignment Length: 353
• Identity: 152/353 - (43%)
• Similarity: 224/353 - (63%)
• Gaps: 8/353 - (2%)

Human    23 AERIMRDSPVIDGHNDLPWQLLDMFNNRLQD-----ERANLTTLA---GTHTNIPKLRAGFVGGQ 79
            |.:::...|:|||||||||.:....:|:|.|     :..|:....   .:||::.:|:.|.:..|
  Fly   698 AVQLLDQVPLIDGHNDLPWNIRKFLHNKLNDFNFDEDLRNVMPWGRSHWSHTDLTRLKKGRISAQ 762

Human    80 FWSVYTPCDTQNKDAVRRTLEQMDVVHRMCRMYPETFLYVTSSAGIRQAFREGKVASLIGVEGGH 144
            ||:.|.||:.|::|||:.||||:||:.|:...|.......||:..|..|.:..::.||.||||||
  Fly   763 FWAAYVPCEAQHRDAVQLTLEQIDVIKRLTDRYSPQLTTCTSAQDIIDAHKNQQLCSLTGVEGGH 827

Human   145 SIDSSLGVLRALYQLGMRYLTLTHSCNTPWADNWLVDTGDSEPQSQGLSPFGQRVVKELNRLGVL 209
            |:..||.|||.||.:|:||:|||.:|:|||||:...|......:..||:.||:.:::|:||||::
  Fly   828 SLGGSLAVLRTLYAIGVRYMTLTSTCHTPWADSSYADAPTFNMKHGGLTIFGKTIIREMNRLGMM 892

Human   210 IDLAHVSVATMKATLQLSRAPVIFSHSSAYSVCASRRNVPDDVLRLVKQTDSLVMVNFYNNYISC 274
            :||:|||..||:..|::|.|||||||||||.:|.:.|||.||:|:.:.:...|||||||:.::||
  Fly   893 VDLSHVSKGTMRDALEVSEAPVIFSHSSAYELCNTSRNVQDDILQALAKNGGLVMVNFYSKFLSC 957

Human   275 TNKANLSQVADHLDHIKEVAGARAVGFGGDFDGVPRVPEGLEDVSKYPDLIAELLRRNWTEAEVK 339
            ::.:.:.....|::|||.|||...||.|..:||:...|:||||||.||.|.||||...||..|:.
  Fly   958 SDNSTVHDAVAHINHIKRVAGIDHVGLGAGYDGINYTPKGLEDVSSYPTLFAELLGGGWTIDELT 1022

Human   340 GALADNLLRVFEAVEQASNLTQAPEEEP 367
            .....|.|||.:.||:..:..:|...:|
  Fly  1023 KLAGGNFLRVMQQVEKLRDDKKAAGVKP 1050

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DPEP1	NP_004404.1	Peptidase_M19	26..352	CDD:395996	147/333 (44%)
CG42750	NP_724101.4	Peptidase_M19	701..1035	CDD:395996	147/333 (44%)