DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ncam1 and DIP-eta

DIOPT Version :9

Sequence 1:XP_006510118.1 Gene:Ncam1 / 17967 MGIID:97281 Length:1162 Species:Mus musculus
Sequence 2:NP_001188701.2 Gene:DIP-eta / 33793 FlyBaseID:FBgn0031725 Length:450 Species:Drosophila melanogaster


Alignment Length:474 Identity:103/474 - (21%)
Similarity:171/474 - (36%) Gaps:167/474 - (35%)


- Green bases have known domain annotations that are detailed below.


Mouse   106 SEATVNVKIFQKLMFKNAPTPQEFKEGEDAVIVCDVVSSLPPTIIWKHKGRDVIL-------KKD 163
            :|..|:.|....::...||.      |.||.:.|.|....|..:.|.......||       .|:
  Fly    37 AEVIVDPKFSSPIVNMTAPV------GRDAFLTCVVQDLGPYKVAWLRVDTQTILTIQNHVITKN 95

Mouse   164 VRFIVLSNNY----LQIRGIKKTDEGTYRCE-GRILARGEINFKDIQVIVNVPPTVQARQSIVNA 223
            .|..:.::.:    ::|:.||::|:|.|.|: .....:.::.:.|    |.|||.:....:..:.
  Fly    96 QRIGIANSEHKTWTMRIKDIKESDKGWYMCQINTDPMKSQMGYLD----VVVPPDILDYPTSTDM 156

Mouse   224 TANLGQSVTLVCDADGFPEPTMSWTKD-GEPIE---NEEEDDEKHIFSDDSSELTIRNVDKNDEA 284
            ....|.:|||.|.|.|.||||::|.:: |.|||   .||      :.|.:.::|.|.||.::...
  Fly   157 VVREGSNVTLKCAATGSPEPTITWRRESGVPIELATGEE------VMSIEGTDLVIPNVRRHHMG 215

Mouse   285 EYVCIAENKAGEQDASIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNI 349
            .|:|||.|                                         |.| ||::        
  Fly   216 AYLCIASN-----------------------------------------GVP-PSVS-------- 230

Mouse   350 SSEEKASWTRPEKQETLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQ 414
                        |:.||..|.                      ..:.|..|              
  Fly   231 ------------KRITLVVHF----------------------PPMITVQN-------------- 247

Mouse   415 YAPKLQGPVAVYTWEGNQVNITCEVFAYPSATISWFRD-GQLLP-----SSNYSNIKIYNTPSAS 473
               :|.|.|     ||..|.:.||..|||.:...|.|: |:::|     |:|.:.|..|.  ::.
  Fly   248 ---QLIGAV-----EGKGVTLDCESEAYPKSINYWTRERGEIVPPGGKYSANVTEIGGYR--NSM 302

Mouse   474 YLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTPSSPSIDRVEPYSSTAQVQFDEPEATGG 538
            .|.:.|.::.:||:|.|.|.|.:|           ||..:..:.|:.|.:......|:       
  Fly   303 RLHINPLTQAEFGSYRCVAKNSLG-----------DTDGTIKLYRIPPNAVNYVENFE------- 349

Mouse   539 VPILKYKAEWKSLGEESWH 557
               .::|.:.::...||.|
  Fly   350 ---ARHKGKKRTKSSESHH 365

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ncam1XP_006510118.1 Ig1_NCAM-1 20..115 CDD:143273 3/8 (38%)
IG 124..190 CDD:214652 18/76 (24%)
Ig3_NCAM-1_like 211..308 CDD:143207 30/100 (30%)
Ig_NCAM-1 307..413 CDD:143277 10/105 (10%)
Ig_3 417..494 CDD:372822 26/82 (32%)
FN3 509..606 CDD:238020 9/49 (18%)
fn3 649..731 CDD:365830
PHA03247 <905..1140 CDD:223021
DIP-etaNP_001188701.2 Ig 51..141 CDD:299845 21/99 (21%)
IG_like 51..137 CDD:214653 20/91 (22%)
IG_like 153..237 CDD:214653 35/151 (23%)
Ig 161..224 CDD:299845 28/109 (26%)
IG_like 252..335 CDD:214653 28/100 (28%)
Ig 258..333 CDD:143165 25/87 (29%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR12231
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
43.910

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