| Sequence 1: | NP_115770.2 | Gene: | Myo7b / 17922 | MGIID: | 107709 | Length: | 2113 | Species: | Mus musculus |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_724569.1 | Gene: | didum / 35680 | FlyBaseID: | FBgn0261397 | Length: | 1800 | Species: | Drosophila melanogaster |
| Alignment Length: | 1697 | Identity: | 478/1697 - (28%) |
|---|---|---|---|
| Similarity: | 735/1697 - (43%) | Gaps: | 369/1697 - (21%) |
- Green bases have known domain annotations that are detailed below.
|
Mouse 26 GIVKETKLGKTLIEDDEGKEHWVHAEDLSTLRPMHPNSAQGVDDMIRLGDLNEAGVVHNLLIRY- 89
Mouse 90 QQHKIYTYTGSILVAVNPFQMLPLYTLEQVQIYYSRHMGELPPHIFAIANSCYFNMKKNKRDQCC 154
Mouse 155 IISGESGAGKTETTKLILQFLATVSGQHS--WIEQQVLEANPILEAFGNAKTIRNDNSSRFGKYI 217
Mouse 218 DIHF-NSSGV--IEGASIEHFLLEKSRVCRQAPEERNYHIFY--CMLMGMSPEEKQMLSLGMPSE 277
Mouse 278 YHYLTMGSCTSSEGLSDAKDYAHVRSAMKILQFSDSENWDISKLLAAILHLGNVGFMAAVF---- 338
Mouse 339 --ENLDSSDVMETPA-FPLAMKLLEVQHQALRDCLIKHTIPVLGEFVSRPVNIAQATDRRDAFVK 400
Mouse 401 GIYGRLFQWIVKKINAAIFTPQAQDPQNVRRAIGLLDIFGFENFQNNSFEQLCINFANEHLQQFF 465
Mouse 466 VKHVFTMEQEEYLSENITWNYIHYTDNQPILDMLALKPMSIISLLDEESRFPQGTDVTMLQKLNS 530
Mouse 531 IHANNK--SFLSPRSIHDTRFGIAHFAGDVYYQAEGFLEKNRDVLSTDILILIHSSKNKFLKEIF 593
Mouse 594 N--------VDSSQTKLGHGTICQVKAGSQLFKSSDSIKRPV-------TLASQFKQSLDQLMRI 643
Mouse 644 LTNCQPYFVRCIKPNEYKKPLLFDRELCIQQLRYSGMMETVHIRKSGFPIRYTFDEFSQRFRVLL 708
Mouse 709 PSPERMQFQNK--PRQMTLHIADLCLG--TDKD-WKVGKTKIFLKDHQDTVLEIRRSQALDGAAI 768
Mouse 769 RIQRVLRGHKYRKEFLRQRRAAVTLQAGWRGYSQRKNFK--------LILVGFER---------- 815
Mouse 816 -------LQAIARSHLLMRQFQAMRQ--RIVQLQARCRGYLVRQQVQAKRRAVVIIQAHARGMVV 871
Mouse 872 RKSYWQQKSTGPQVILAKEPKAQVAVHERKRKSIYDTVTDTAMVEKVFGFLPAMIGGQEGPAPTR 936
Mouse 937 FEDLEVKTQKL-HEVDLDTVPMMAMPEEEVDSLAEYTFPKFAVTYFQKSASHTHIQKPLRYPLLY 1000
Mouse 1001 HENDTDHSAALDVWIIILRFMGDLPEPVVYGRNS--LTGSSVMRQIHD--KLGKDS-VTQHNRSS 1060
Mouse 1061 QVASQLNFGEEAFKFDGPISDRPMSNLEKVHFI------------------------------VG 1095
Mouse 1096 YAIMR--------PGLRDEIYC-------------------QICKQLSENY-KTSSRARGWILLS 1132
Mouse 1133 LCLGCFPPSERFMKYLLNFISQGPPS-YGPFCAERLQRTFANGVRAEPPTWLELQAVKSKKHIPI 1196
Mouse 1197 QVILATGRSLTISVDSASTSREICQH-----VAQKQGLRDNLGFSLQVAVYDKFWSLGSGCDHLM 1256
Mouse 1257 DAVAQCEQLARERGESQRQAPWRIYFRKEFFTPWHDSQEDPVSTELIYHQVLRGVWSGEYNFEKE 1321
Mouse 1322 E-----------------------------ELVELLARHCYVQLG---ATVKSNAVQE---LLPS 1351
Mouse 1352 CVPSKLYRTKSPEKWASLVTAAHAKAQYTQSKA-TPLAVRE-QTVEAARLLWPLLFSRLFEVTTL 1414
Mouse 1415 SG--PRLPKTQLVLAINWKGMYFLDQKERTLLGLSFAEVMGL------VANRDAPGGKKLLLATL 1471
Mouse 1472 QEEYEFVSPSSVAIAEMVALFLGGLKERSVFAMALQDRRATDDITLLPFKKG--DLLI------L 1528
Mouse 1529 TKKQGLL 1535 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Myo7b | NP_115770.2 | MYSc | 60..759 | CDD:214580 | 289/735 (39%) |
| MYSc_Myo7 | 79..748 | CDD:276832 | 280/705 (40%) | ||
| Actin-binding. /evidence=ECO:0000255|PROSITE-ProRule:PRU00782 | 637..659 | 10/21 (48%) | |||
| IQ | 785..807 | CDD:197470 | 6/21 (29%) | ||
| Mediates interaction with ANKS4B. /evidence=ECO:0000269|PubMed:26812017 | 962..1578 | 124/696 (18%) | |||
| MyTH4 | 989..1189 | CDD:214535 | 47/263 (18%) | ||
| B41 | 1196..1409 | CDD:214604 | 47/254 (19%) | ||
| FERM_B-lobe | 1299..1400 | CDD:271216 | 23/137 (17%) | ||
| FERM_C1_MyoVII | 1403..1499 | CDD:270019 | 17/103 (17%) | ||
| Mediates interaction with CDHR2, CDHR5 and USH1C. /evidence=ECO:0000250|UniProtKB:Q6PIF6 | 1497..2113 | 10/47 (21%) | |||
| SH3 | 1500..1560 | CDD:302595 | 9/44 (20%) | ||
| MyTH4 | 1641..1788 | CDD:214535 | |||
| B41 | 1797..2009 | CDD:214604 | |||
| FERM_M | 1907..2009 | CDD:278785 | |||
| FERM_C2_MyoVII | 2005..2100 | CDD:270020 | |||
| didum | NP_724569.1 | MYSc | 65..778 | CDD:214580 | 289/735 (39%) |
| MYSc_Myo5 | 84..767 | CDD:276831 | 280/705 (40%) | ||
| IQ | 900..922 | CDD:197470 | 7/21 (33%) | ||
| GBP_C | <971..1086 | CDD:303769 | 23/130 (18%) | ||
| coiled coil | 1049..1068 | CDD:293879 | 4/18 (22%) | ||
| coiled coil | 1077..1086 | CDD:293879 | 1/8 (13%) | ||
| JAKMIP_CC3 | <1190..1299 | CDD:292653 | 30/154 (19%) | ||
| Myo5_CBD | 1424..1792 | CDD:271254 | 28/157 (18%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 1 | 0.900 | - | - | OOG6_100101 | |
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 2.810 | |||||