DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hpo-9 and rdx

DIOPT Version :9

Sequence 1:	NP_504839.1	Gene:	hpo-9 / 179117	WormBaseID:	WBGene00015463	Length:	581	Species:	Caenorhabditis elegans
Sequence 2:	NP_650326.3	Gene:	rdx / 41704	FlyBaseID:	FBgn0264493	Length:	829	Species:	Drosophila melanogaster

Alignment Length:	235	Identity:	61/235 - (25%)
Similarity:	105/235 - (44%)	Gaps:	43/235 - (18%)

- Green bases have known domain annotations that are detailed below.

Worm    13 EDGRGIVE----TMRTESAAISNNFNAVNSVNKSVVQHL---DELSQSFDEIFTSTDHSDVTLVL 70
            ::..|::.    |:..|.:.::::.|.  |...::||..   .:||:....:|.:...|||||.:
  Fly   599 DEANGLLPEDKLTIFCEVSVVADSVNI--SGQSNIVQFKVPECKLSEDLGNLFDNEKFSDVTLSV 661

Worm    71 DDGTEFAAHRLILAVRSSFFRAMLYTGFQESHQQLVTLQETNSVAFRAVLRYMYTSKIDFAGVEL 135
             .|.||.||:.|||.||..|.||.....:|.....|.:.:.:....:.:||::||.|........
  Fly   662 -GGREFQAHKAILAARSDVFAAMFEHEMEERKLNRVAITDVDHEVLKEMLRFIYTGKAPNLEKMA 725

Worm   136 DILLEYLSLAHRYDLIQLMTAISEYFKEILKNENLC---SIFNAAYFFQFTDL----------ID 187
            |   :.|:.|.:|.|.:|         :::..|.||   |:..||......||          ||
  Fly   726 D---DLLAAADKYALEKL---------KVMCEEALCVNLSVETAAETLILADLHSADQLKAQTID 778

Worm   188 YCMQYSDKHADQLLEDPSF-NRLSGDSLKELLARDSFFAL 226
            :.    :.||..::|...: |.::..|  .|:| ::|.||
  Fly   779 FI----NTHATDVMETSGWQNMITTHS--HLIA-EAFRAL 811

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hpo-9	NP_504839.1	BTB_POZ_BTBD9	42..161	CDD:349596	36/121 (30%)
		BACK_BTBD9	165..265	CDD:350518	20/76 (26%)
		F5_F8_type_C	461..557	CDD:366285
rdx	NP_650326.3	MATH_SPOP	483..621	CDD:239743	3/21 (14%)
		BTB	645..749	CDD:279045	33/116 (28%)
		BTB	656..752	CDD:197585	33/108 (31%)
		SPOP_C	752..814	CDD:269807	17/67 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910