Protein Alignment exp-2 and Shawl

DIOPT Version :10

• Sequence 1: NP_001367760.1
• Gene: exp-2 / 179003
• WormBaseID: WBGene00001374
• Length: 510
• Species: Caenorhabditis elegans
• Sequence 2: NP_001097131.2
• Gene: Shawl / 5740840
• FlyBaseID: FBgn0085395
• Length: 937
• Species: Drosophila melanogaster
• Alignment Length: 516
• Identity: 132/516 - (25%)
• Similarity: 209/516 - (40%)
• Gaps: 144/516 - (27%)

 Worm    81 LNIGGTSFMILIDAILRADTTTFLSRFVQLTHTARLKVADA-YISADDAYYFQRSPTSFEAVFQY 144
            ||:.|          :|.:|.....:.:..|..:||..|.| |....:.|:|.|.|..|..:..|
  Fly     9 LNVSG----------IRYETYKATLKKIPATRLSRLTEALANYDPVLNEYFFDRHPGVFTQILNY 63

 Worm   145 YATGVVHRPSEICPASFLSELDFWRISHQHVGSCC-------------------ADIIPQKREEE 190
            |.||.:|.|:::|...|..||:||.:....|..||                   .||..:|..||
  Fly    64 YRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWSTYSIHRDTQNTLAILDKLDIENEKPTEE 128

 Worm   191 K------EEEKVDDTTFDKLMC-GKLRRRMWTFLERPGSSMQAKAFELSSTLFVAISVMGLSFGT 248
            :      .||.:.:   .:|.| .:::.::|...:.|.||..||.....|..|:.:||:.....|
  Fly   129 QIARLFGFEEALSN---GELNCWQRIKPKIWAMFDEPSSSTGAKIVAGMSVFFIFVSVISFCLKT 190

 Worm   249 IPDFQV-----------------------------THLMPPHNETVVLPNGT------------- 271
            .|.|:|                             ||..  |..::..|:|:
  Fly   191 HPGFRVDLPSGAHDAHGPGAGGPPHGHDPMGEPPQTHQY--HQHSITPPSGSIGPTFRVTNYTSY 253

 Worm   272 -------------VTVVQKVEQMRVE----------------------------------HPAFV 289
                         :..::..::.|::                                  |.||.
  Fly   254 SSGNFTASGQATPIATIKGGQRQRLKRNINGSILNEFIEEKILGHNGRRKHGWIETYGQPHEAFF 318

 Worm   290 FTERICIAFFTVEYCLRFFAAPRKLRFALKPLNLVDLLAIVPFYLELLLTLCGVDDRKLRDLRWA 354
            :.|.:|..:|.:|..:|...:|...:|...|:|::|..|.:.||.:::..:     .:...|..|
  Fly   319 YVELVCNVWFFIEVIIRLIVSPNLWQFIKSPVNIIDFTATLSFYTDVMQRM-----GEYTGLLEA 378

 Worm   355 FLVVRILRVLRVIRIIKLGRFSSGLQTFGMTLQRSQKQLQMMTIVLLTGVVFFSTMIYFLEK--D 417
            |.:|||:      |:.||.|.|.||:....|.:.|.|:|.::...|:.|:|||:::.|:.||  |
  Fly   379 FSIVRIM------RLFKLTRHSPGLRILIHTFKASAKELTLLVFFLVLGIVFFASLAYYAEKLQD 437

 Worm   418 EEGTPFTSIPAAYWWCIVTMTTVGYGDAVPATTMGKIIASAAIMCGVLVLALPITIIVDNF 478
            .....|.|||...||.|||||||||||..|.|..|..:.:...:.|||.:|||:.:||.||
  Fly   438 NPDNQFKSIPLGLWWAIVTMTTVGYGDVAPKTYPGMFVGALCALAGVLTIALPVPVIVSNF 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
exp-2	NP_001367760.1	BTB_2	79..178	CDD:426665	29/97 (30%)
		Ion_trans	292..478	CDD:459842	67/187 (36%)
Shawl	NP_001097131.2	BTB_Shaw-like	4..115	CDD:349723	31/115 (27%)
		Ion_trans	307..506	CDD:459842	72/203 (35%)