Protein Alignment Myh6 and Prm

DIOPT Version :9

• Sequence 1: XP_006518740.1
• Gene: Myh6 / 17888
• MGIID: 97255
• Length: 1939
• Species: Mus musculus
• Sequence 2: NP_523982.2
• Gene: Prm / 39002
• FlyBaseID: FBgn0003149
• Length: 879
• Species: Drosophila melanogaster
• Alignment Length: 832
• Identity: 291/832 - (34%)
• Similarity: 498/832 - (59%)
• Gaps: 15/832 - (1%)

Mouse  1104 LQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKK 1168
            :|....|...:.:|..|:::||.||..|.::|:.::|||.::.::|||||||.|....|.|.|:|
  Fly    31 IQDLSSLSRLEDKIRLLQDDLEVERELRQRIEREKADLSVQVIQMSERLEEAEGGAEHQFEANRK 95

Mouse  1169 REAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDV 1233
            |:||..|:|:.||:..|:.|.|...|:|||.:.:.:..||::.|.:.|.:.||:|::|:.|:.::
  Fly    96 RDAELLKLRKLLEDVHLESEETTLLLKKKHNEIITDFQEQVEILTKNKARAEKDKAKFQTEVYEL 160

Mouse  1234 TSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEA 1298
            .|.:|...|.|...||....||...:|..||:||..|::.|.::.|::|..||.||.:.:::.:.
  Fly   161 LSQIESYNKEKIVSEKHISKLEVSISELNVKIEELNRTVIDISSHRSRLSQENIELTKDVQDLKV 225

Mouse  1299 LISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSSRHDCDLLREQYEEEMEAKAELQRVL 1363
            .:..::..|.....|:||.:|:||:|.:.::.|..:|.....:.|.:|.|.|||.||:.:|:|.|
  Fly   226 QLDTVSFSKSQVISQLEDARRRLEDEDRRRSLLESSLHQVEIELDSVRNQLEEESEARIDLERQL 290

Mouse  1364 SKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIE 1428
            .|||::...|:.|:.::...|.||:||.::|...|:.:.||.:|::..|.::|||.|.||.:|:|
  Fly   291 VKANADATSWQNKWNSEVAARAEEVEEIRRKYQVRITELEEHIESLIVKVNNLEKMKTRLASEVE 355

Mouse  1429 DLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEES 1493
            .|::|:|:||.:...|.|.....:|...|.|.:.:|:....|:||::.::...:|.:..:..::.
  Fly   356 VLIIDLEKSNNSCRELTKSVNTLEKHNVELKSRLDETIILYETSQRDLKNKHADLVRTVHELDKV 420

Mouse  1494 LEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKIRKQLEVEKLELQSALEEAEASLEHEEG 1558
            .::.....||||.|.:::.:....:.|..:.:||||...::||.|:.||.:|.:||||..:.||.
  Fly   421 KDNNNQLTRENKKLGDDLHEAKGAINELNRRLHELELELRRLENERDELTAAYKEAEAGRKAEEQ 485

Mouse  1559 KILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRMVDSLQTS-LDAETRSRNEALRVKKKMEG 1622
            :..|...:|||.:.:.||:|||||||:|..::.....::.|... ::||||.:.|..|:|||::.
  Fly   486 RGQRLAADFNQYRHDAERRLAEKDEEIEAIRKQTSIEIEQLNARVIEAETRLKTEVTRIKKKLQI 550

Mouse  1623 DLNEMEIQLSQANRIASEAQKHLKNS-------QAHLKDTQLQLDDAVHANDDLKENIAIVERRN 1680
            .:.|:|:.|..||:...:.||.:|..       |||.:|.|.||...:       :..|:.:||.
  Fly   551 QITELEMSLDVANKTNIDLQKVIKKQSLQLTELQAHYEDVQRQLQATL-------DQYAVAQRRL 608

Mouse  1681 NLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQTEVEE 1745
            ..|..||||:|:.::...|:::..|.:..|.:.|:..|.:.|.||::.|.|:|.:|:.:.::.||
  Fly   609 AGLNGELEEVRSHLDSANRAKRTVELQYEEAASRINELTTANVSLVSIKSKLEQELSVVASDYEE 673

Mouse  1746 AVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGG 1810
            ..:|.|.::|:.:|...:...:.|::.:||:....||.:||::|..:|:|..||:|.|..|:.|.
  Fly   674 VSKELRISDERYQKVQVELKHVVEQVHEEQERIVKLETIKKSLEVEVKNLSIRLEEVELNAVAGS 738

Mouse  1811 KKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLMRLQDLVDKLQL 1875
            |:.:.|||||:|:||.|||.|::|:||::|.:||.||.:||:..|.|||:|||:.|||.:||...
  Fly   739 KRIISKLEARIRDLELELEEEKRRHAETIKILRKKERTVKEVLVQCEEDQKNLILLQDALDKSTA 803

Mouse  1876 KVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSR 1927
            |:..|:||..|.|..:....::.|:.|.||:.||:|||.|||.:|.:|||.|
  Fly   804 KINIYRRQLSEQEGVSQQTTTRVRRFQRELEAAEDRADTAESSLNIIRAKHR 855

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myh6	XP_006518740.1	Myosin_N	34..72	CDD:367160
		MYSc_class_II	99..768	CDD:276951
		Myosin_tail_1	848..1925	CDD:366712	288/828 (35%)
Prm	NP_523982.2	Myosin_tail_1	<34..853	CDD:279860	287/825 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0161
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810