Protein Alignment Myh3 and Prm

DIOPT Version :9

• Sequence 1: NP_001093105.1
• Gene: Myh3 / 17883
• MGIID: 1339709
• Length: 1940
• Species: Mus musculus
• Sequence 2: NP_523982.2
• Gene: Prm / 39002
• FlyBaseID: FBgn0003149
• Length: 879
• Species: Drosophila melanogaster
• Alignment Length: 851
• Identity: 295/851 - (34%)
• Similarity: 505/851 - (59%)
• Gaps: 15/851 - (1%)

Mouse  1085 DFEYSQLQSKVEDEQTLSLQLQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSE 1149
            :.||      ::|..:|| :|:.||:.||       :::|.||..|.:.|::::|.:.::.::||
  Fly    27 NIEY------IQDLSSLS-RLEDKIRLLQ-------DDLEVERELRQRIEREKADLSVQVIQMSE 77

Mouse  1150 RLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEATVATLRKKHADSAAELAEQIDNLQRV 1214
            |||||.|....|.|.|:||:||.||||:.||:..|:.|.|...|:|||.:...:..||::.|.:.
  Fly    78 RLEEAEGGAEHQFEANRKRDAELLKLRKLLEDVHLESEETTLLLKKKHNEIITDFQEQVEILTKN 142

Mouse  1215 KQKLEKEKSEFKLEIDDLSSSVESVSKSKANLEKICRTLEDQLSEARGKNEEMQRSLSELTTQKS 1279
            |.:.||:|::|:.|:.:|.|.:||.:|.|...||....||..:||...|.||:.|::.::::.:|
  Fly   143 KARAEKDKAKFQTEVYELLSQIESYNKEKIVSEKHISKLEVSISELNVKIEELNRTVIDISSHRS 207

Mouse  1280 RLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQIEELKRQLEEENKAKNALAHALQSSRHDCDLL 1344
            ||..|..||::.:::.:..:..:|.||.....|:|:.:|:||:|::.::.|..:|.....:.|.:
  Fly   208 RLSQENIELTKDVQDLKVQLDTVSFSKSQVISQLEDARRRLEDEDRRRSLLESSLHQVEIELDSV 272

Mouse  1345 REQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVN 1409
            |.|.|||.|.:.:|:|.|.|||::...|:.|:.::...|.||:||.::|...|:.:.||.:|::.
  Fly   273 RNQLEEESEARIDLERQLVKANADATSWQNKWNSEVAARAEEVEEIRRKYQVRITELEEHIESLI 337

Mouse  1410 AKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEAALKE 1474
            .|..:|||.|.||..|||.|::|:|::|:....|.|.....:|...|.|::.:|:....|.:.::
  Fly   338 VKVNNLEKMKTRLASEVEVLIIDLEKSNNSCRELTKSVNTLEKHNVELKSRLDETIILYETSQRD 402

Mouse  1475 SRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKSIHELEKSRKQMELEKA 1539
            .::...:|.:..:..::..|....:.||||.|..::.:....|.|..:.:||||...:::|.|:.
  Fly   403 LKNKHADLVRTVHELDKVKDNNNQLTRENKKLGDDLHEAKGAINELNRRLHELELELRRLENERD 467

Mouse  1540 DIQMALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQG-ALD 1603
            ::..|.:||||..:.||.:..|:..:..|.:.:.:|::||||||||.:::.....:|.:.. .::
  Fly   468 ELTAAYKEAEAGRKAEEQRGQRLAADFNQYRHDAERRLAEKDEEIEAIRKQTSIEIEQLNARVIE 532

Mouse  1604 AEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETIKHLRSVQGQLKDTQLHLDDALRGQEDL 1668
            ||.|.:.|..|:|||::..:.|:|:.|..||:...:..|.::....||.:.|.|.:|..|..:..
  Fly   533 AETRLKTEVTRIKKKLQIQITELEMSLDVANKTNIDLQKVIKKQSLQLTELQAHYEDVQRQLQAT 597

Mouse  1669 KEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLET 1733
            .:|.|:.:||...|..|:||:|:.|:...||::..|.:..::..|:..|.|.|.||:..|.|||.
  Fly   598 LDQYAVAQRRLAGLNGELEEVRSHLDSANRAKRTVELQYEEAASRINELTTANVSLVSIKSKLEQ 662

Mouse  1734 DLTQLQSEVEDACRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRL 1798
            :|:.:.|:.|:..::.|.::|:.:|...:...:.|::.:||:....||.:||:||..||:|..||
  Fly   663 ELSVVASDYEEVSKELRISDERYQKVQVELKHVVEQVHEEQERIVKLETIKKSLEVEVKNLSIRL 727

Mouse  1799 DEAEQLALKGGKKQIQKLETRIRELEFELEGEQKRNTESVKGLRKYERRVKELTYQSEEDRKNVL 1863
            :|.|..|:.|.|:.|.|||.|||:||.|||.|::|:.|::|.|||.||.|||:..|.|||:||::
  Fly   728 EEVELNAVAGSKRIISKLEARIRDLELELEEEKRRHAETIKILRKKERTVKEVLVQCEEDQKNLI 792

Mouse  1864 RLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLRAKTRDF 1928
            .|||.:||...|:..|:||..|.:..:....|:.|:.|.|||.||:|||.|||.:|.:|||.|.|
  Fly   793 LLQDALDKSTAKINIYRRQLSEQEGVSQQTTTRVRRFQRELEAAEDRADTAESSLNIIRAKHRTF 857

Mouse  1929 TSSRMV 1934
            .::..|
  Fly   858 VTTSTV 863

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myh3	NP_001093105.1	Myosin_N	35..73	CDD:367160
		MYSc_Myh3	100..767	CDD:276878
		Actin-binding. /evidence=ECO:0000250	656..678
		Actin-binding. /evidence=ECO:0000250	758..772
		Myosin_tail_1	847..1924	CDD:366712	290/839 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1260..1289		9/28 (32%)
Prm	NP_523982.2	Myosin_tail_1	<34..853	CDD:279860	287/826 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0161
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810