Protein Alignment Myh11 and Prm

DIOPT Version :9

• Sequence 1: XP_006521906.1
• Gene: Myh11 / 17880
• MGIID: 102643
• Length: 1979
• Species: Mus musculus
• Sequence 2: NP_523982.2
• Gene: Prm / 39002
• FlyBaseID: FBgn0003149
• Length: 879
• Species: Drosophila melanogaster
• Alignment Length: 883
• Identity: 236/883 - (26%)
• Similarity: 424/883 - (48%)
• Gaps: 84/883 - (9%)

Mouse  1117 LKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQ 1181
            |..:..||..|..||:||:.||..|.:.|::|.||..::..:...||:.......|.|...||:.
  Fly    34 LSSLSRLEDKIRLLQDDLEVERELRQRIEREKADLSVQVIQMSERLEEAEGGAEHQFEANRKRDA 98

Mouse  1182 EVTVLKKALDEETRSHEAQVQEMRQKHTQAVEELTEQLEQFKRAKANLDKSKQTLEKENADLAGE 1246
            |:..|:|.|::.....|.....:::||.:.:.:..||:|...:.||..:|.|...:.|..:|..:
  Fly    99 ELLKLRKLLEDVHLESEETTLLLKKKHNEIITDFQEQVEILTKNKARAEKDKAKFQTEVYELLSQ 163

Mouse  1247 LRVLGQAKQEVEHKKKKLEVQLQDLQSKCSDGERARAELSDKVHKLQNEVESVTGMLNEAEGKAI 1311
            :....:.|...|....||||.:.:|..|..:..|...::|....:|..|              .|
  Fly   164 IESYNKEKIVSEKHISKLEVSISELNVKIEELNRTVIDISSHRSRLSQE--------------NI 214

Mouse  1312 KLAKDVASLG--------------SQLQDTQELLQEETRQKLNVSTKLRQLEDERNSLQDQLDEE 1362
            :|.|||..|.              |||:|.:..|::|.|::..:.:.|.|:|.|.:|:::||:||
  Fly   215 ELTKDVQDLKVQLDTVSFSKSQVISQLEDARRRLEDEDRRRSLLESSLHQVEIELDSVRNQLEEE 279

Mouse  1363 MEAKQNLERHVSTLNIQLSDSKKKL-QDFASTIEVMEEGKKRLQKEMEGLSQQYEEKAAAYDKLE 1426
            .||:.:|||.:...|...:..:.|. .:.|:..|.:||.:::.|..:..|.:..|......:.||
  Fly   280 SEARIDLERQLVKANADATSWQNKWNSEVAARAEEVEEIRRKYQVRITELEEHIESLIVKVNNLE 344

Mouse  1427 KTKNRLQQELDDLVVDLDNQ----RQL---VSNLEKKQKKFDQLLAE--------EKNISSKYAD 1476
            |.|.||..|::.|::||:..    |:|   |:.|||...:....|.|        ::::.:|:||
  Fly   345 KMKTRLASEVEVLIIDLEKSNNSCRELTKSVNTLEKHNVELKSRLDETIILYETSQRDLKNKHAD 409

Mouse  1477 ERDRAEAEAREKETKALSLARALEEALEAKE---ELERTNKMLKAEMEDLVSSKDDVGKNVHELE 1538
                              |.|.:.|..:.|:   :|.|.||.|..::.:...:.:::.:.:||||
  Fly   410 ------------------LVRTVHELDKVKDNNNQLTRENKKLGDDLHEAKGAINELNRRLHELE 456

Mouse  1539 KSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQR 1603
            ...|.||.:.:|:....:|.|...:|.|....||..:....:...||.|..:||:.|..|:|...
  Fly   457 LELRRLENERDELTAAYKEAEAGRKAEEQRGQRLAADFNQYRHDAERRLAEKDEEIEAIRKQTSI 521

Mouse  1604 QLHEYETE-LEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGR---EEAIK----QLRKLQAQ 1660
            ::.:.... :|.|.:.:......||||:..:.:||:..|.|.|..   ::.||    ||.:|||.
  Fly   522 EIEQLNARVIEAETRLKTEVTRIKKKLQIQITELEMSLDVANKTNIDLQKVIKKQSLQLTELQAH 586

Mouse  1661 MKDFQRELDDARASRDEIFATSKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELA 1725
            .:|.||:|   :|:.|: :|.:   :::...|..:|.:::..|.:|.||::..:|:.||.|..:.
  Fly   587 YEDVQRQL---QATLDQ-YAVA---QRRLAGLNGELEEVRSHLDSANRAKRTVELQYEEAASRIN 644

Mouse  1726 SSLSGRNTLQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATLQAEQLSNELATERSTAQKN 1790
            ...:...:|...|.:||..::.:..:.||....:....:|.:|..::.:.:..::..|:....|.
  Fly   645 ELTTANVSLVSIKSKLEQELSVVASDYEEVSKELRISDERYQKVQVELKHVVEQVHEEQERIVKL 709

Mouse  1791 ESARQQLERQNKELRSKLQEVEGAVKAKLKSTVAALEAKIAQLEEQVEQEAREKQAATKSLKQKD 1855
            |:.::.||.:.|.|..:|:|||....|..|..::.|||:|..||.::|:|.|......|.|::|:
  Fly   710 ETIKKSLEVEVKNLSIRLEEVELNAVAGSKRIISKLEARIRDLELELEEEKRRHAETIKILRKKE 774

Mouse  1856 KKLKEVLLQVEDERKMAEQYKEQAEKGNTKVKQLKRQLEEAEEESQRINANRRKLQRELDEATES 1920
            :.:||||:|.|:::|.....::..:|...|:...:|||.|.|..||:.....|:.||||:.|.:.
  Fly   775 RTVKEVLVQCEEDQKNLILLQDALDKSTAKINIYRRQLSEQEGVSQQTTTRVRRFQRELEAAEDR 839

Mouse  1921 NEAMGREVNALKSKLRRGNEASFVPSRRAGGRRVIENT 1958
            .:.....:|.:::|.|.....|.||    |.:..|:.|
  Fly   840 ADTAESSLNIIRAKHRTFVTTSTVP----GSQVYIQET 873

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myh11	XP_006521906.1	Myosin_N	33..71	CDD:367160
		MYSc_class_II	99..778	CDD:276951
		Myosin_tail_1	855..1935	CDD:366712	228/858 (27%)
Prm	NP_523982.2	Myosin_tail_1	<34..853	CDD:279860	228/857 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0161
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810