Protein Alignment DYNC1LI2 and Dlic

DIOPT Version :10

• Sequence 1: NP_006132.1
• Gene: DYNC1LI2 / 1783
• HGNCID: 2966
• Length: 492
• Species: Homo sapiens
• Sequence 2: NP_572694.1
• Gene: Dlic / 32057
• FlyBaseID: FBgn0030276
• Length: 493
• Species: Drosophila melanogaster
• Alignment Length: 486
• Identity: 219/486 - (45%)
• Similarity: 299/486 - (61%)
• Gaps: 35/486 - (7%)

Human    24 DLTSEEEEGQSLWSSILSEVSTRARSKLPSGKNILVFGEDGSGKTTLMTKLQGAEHGKKGRGLEY 88
            |..:|:|   :|||:||:||.|:..:||||.|::||.|::.:|||||:.||||.|..|||.||||
  Fly    22 DAAAEKE---NLWSAILNEVQTQGSTKLPSNKSVLVLGDNATGKTTLIAKLQGVEDPKKGSGLEY 83

Human    89 LYLSVHDEDRDDHTRCNVWILDGDLYHKGLLKFAVSAESLPETLVIFVADMSRPWTVMESLQKWA 153
            .|:.|.||.|||.||..||:||||..|..||.:|::..:...||||....|::||..:|.|..|.
  Fly    84 AYIDVKDEYRDDMTRLGVWVLDGDPGHTNLLHYALNETNYAHTLVILTVSMTQPWGWLEQLNHWI 148

Human   154 SVLREHIDKMKIPPEKMRELERKFVKDFQDYMEPEEGCQ-GSPQRRGPLTSGSDEENVALPLGDN 217
            .||.:|||.:::..::.....::....:|.|.|..:... |||.:|....:..||::: |||.::
  Fly   149 KVLGQHIDSLQLDAKEKEAARQRLTTTWQSYCEVGDDLDPGSPVKRTMRNNSIDEDDL-LPLTED 212

Human   218 VLTHNLGIPVLVVCTKCDAVSVLEKEHDYRDEHLDFIQSHLRRFCLQYGAALIYTSVKEEKNLDL 282
            .|..|||:.::||.||.|.::.||||::|||||.||||..:|.|||::|.:|.||||||:||.|:
  Fly   213 ALITNLGLDIVVVVTKTDYMTTLEKEYEYRDEHFDFIQQWIRNFCLRHGTSLFYTSVKEDKNCDV 277

Human   283 LYKYIVHKTYGFHFTTPALVVEKDAVFIPAGWDNEKKIAILHENFTTVKPEDAYEDFIVKPPVRK 347
            ||||:.|:.||..|.|||||||||||.||||||:.|||:||:||...||.|:.|.|.|..||.||
  Fly   278 LYKYLTHRIYGLPFRTPALVVEKDAVLIPAGWDSLKKISILYENMHGVKAENPYTDIIKSPPTRK 342

Human   348 LVHDK--ELAAEDEQVFLMKQQSLLAKQPATPTRASESPARGPSGSPRTQGRGGPASVPSSSPGT 410
            .|.::  |:..||||.||.:||.:|.:....   ..|||.       |:||.|...|.| .:|||
  Fly   343 AVSNREAEVQTEDEQAFLARQQEILKQGDQV---RGESPL-------RSQGVGSNKSGP-RTPGT 396

Human   411 ----SVKKPDPNI-KNNAASEGVLASFFNSLLSKKTGSPGSPGAGGVQSTA----KKSGQKTVL- 465
                |.||.||.: .....:|||||:||||||.||:||||:.|.||..:.|    ..:|...|:
  Fly   397 TGQSSPKKIDPKLTPATPGAEGVLANFFNSLLHKKSGSPGTGGPGGAGNPAGPGRTANGTDAVMT 461

Human   466 -------SNVQEELDRMTRKPDSMVTNSSTE 489
                   ::...||||::|.....:..|.:|
  Fly   462 PEKLAVRTDAAAELDRLSRSVKKEIDMSQSE 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DYNC1LI2	NP_006132.1	DLIC	30..488	CDD:368612	216/477 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	187..206		4/19 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	371..423		17/56 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	437..492		20/65 (31%)
Dlic	NP_572694.1	DLIC	25..489	CDD:368612	216/478 (45%)