DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rbm-17 and Spf45

DIOPT Version :9

Sequence 1:	NP_502198.1	Gene:	rbm-17 / 178091	WormBaseID:	WBGene00010233	Length:	371	Species:	Caenorhabditis elegans
Sequence 2:	NP_001036426.1	Gene:	Spf45 / 3355114	FlyBaseID:	FBgn0086683	Length:	403	Species:	Drosophila melanogaster

Alignment Length:	413	Identity:	117/413 - (28%)
Similarity:	169/413 - (40%)	Gaps:	128/413 - (30%)

- Green bases have known domain annotations that are detailed below.

Worm    41 LQQQAARQKLVKSSAPPPVIDLSTR---NRTIT-----TAVTSKSFQPIRANPVSDNISFLPKAA 97
            ||.|.|.:..||.....||::|.::   :..:|     |.|.||.....:|.|     |.|.:..
  Fly    26 LQTQLAVKMAVKKPLMTPVVNLRSKRLADPEVTCFAPITTVVSKPLISGKALP-----SILERIN 85

Worm    98 TDESVMLFGEEHVKCEYYPMTPNNYEVVAKEINDRKQREKTAREVAKRLQREHEEEDKKRSK--- 159
            .       |:..|..||.|..||.||.:.::.|.   .:|....|:.|..|:.:|:|:||.:
  Fly    86 R-------GDWDVADEYDPQRPNEYEKLKEKSNG---SDKNRAGVSDREDRDDKEKDRKRGRVGR 140

Worm   160 ---------------------------------------GAAIAPPTMLMEPEPEVIKNTNENQD 185
                                                   ||.||||..|.|..   |.:..|..:
  Fly   141 REFYRDEVSAPNLKLSGFGHRQNDDDMYLPSPGLVAKQGGATIAPPPSLQEMS---IDSGCEATN 202

Worm   186 EKPHSSFMPPPSFLPAFGKATSRGLGIAANIMKRHGYKEGAGLGKSEQGMSTALSIEKTGVRGGN 250
            ..|:|              |:|    :||.||.::|:|:|.|||||||||:.||.:|||..|||.
  Fly   203 TMPYS--------------ASS----VAAKIMAKYGFKDGQGLGKSEQGMAIALQVEKTSKRGGR 249

Worm   251 IVAE-----------------------------APKAPTFATNS-------MEAVQNATKILQLW 279
            |:.|                             .|:....|..|       .|.:::.:|::.|.
  Fly   250 IIHEKDVFLPPLALSPPSIGSQIGTSPSHKAMPPPQMVDTAAESGDIGYSITEIMKSPSKVVLLR 314

Worm   280 NLTDLSEVSGEEGKKEFADEIKEEME-KCGQVVNVIVHVDESQEEDRQVRVFVEFTNNAQAIKAF 343
            |:....:|.     :|...|:|:|.. |.|:|.:||:|.......:..|::||||.....||||.
  Fly   315 NMVGPGDVD-----EELEPEVKDECNTKYGEVNSVIIHESFGTVPEDAVKIFVEFRRIESAIKAV 374

Worm   344 VMMNGRFFGGRSVSAGFQNVSDY 366
            |.:||||||||.|.|||.|...:
  Fly   375 VDLNGRFFGGRQVRAGFYNYDKF 397

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rbm-17	NP_502198.1	G-patch	211..254	CDD:279867	25/42 (60%)
rbm-17	NP_502198.1	RRM_UHM_SPF45_PUF60	273..362	CDD:240820	36/89 (40%)
Spf45	NP_001036426.1	G-patch	209..248	CDD:279867	23/42 (55%)
Spf45	NP_001036426.1	RRM_UHM_SPF45	307..402	CDD:241091	37/96 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159645
Domainoid	1	1.000	55	1.000	Domainoid score	I7433
eggNOG	1	0.900	-	-		E1_KOG1996
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H13162
Inparanoid	1	1.050	118	1.000	Inparanoid score	I3358
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60100
OrthoDB	1	1.010	-	-		D1101846at2759
OrthoFinder	1	1.000	-	-		FOG0005833
OrthoInspector	1	1.000	-	-		oto19421
orthoMCL	1	0.900	-	-		OOG6_103640
Panther	1	1.100	-	-	LDO	PTHR13288
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3833
SonicParanoid	1	1.000	-	-		X4816
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	16	15.840