|
Human 46 VYTNYPFPGET-FNREKFRSLDWENPTEREDDSDKYCKLNLQQSGSFQYY--FLQGNEK---SGG 104
|:||.|....| |.|:||......:....:|..| ||:...||:.:| |...||| :..
Yeast 62 VWTNCPPDHNTPFKRDKFYKKIIHSSFHEDDCID----LNVYAPGSYCFYLSFRNDNEKLETTRK 122
Human 105 GYIVVDPILRVGADNHVLPLDCVTLQTFLAKCLGPFDEWESRLRVAKESGYNMIHFTPLQTLGLS 169
.|.|..|:|.: ::..|||:.:.||:.::|.|| .:||..|.......|||:||||||..|.|
Yeast 123 YYFVALPMLYI--NDQFLPLNSIALQSVVSKWLG--SDWEPILSKIAAKNYNMVHFTPLQERGES 183
Human 170 RSCYSLANQLELNPD-FSRPNRKYTWNDVGQLVEKLKKEWNVICITDVVYNHTAANSKWIQEHPE 233
.|.||:.:||:.:.: |..| .||..|||.:.::.|::.:||:|:||||.||.|:.||||
Yeast 184 NSPYSIYDQLQFDQEHFKSP------EDVKNLVEHIHRDLNMLSLTDIVFNHTANNSPWLVEHPE 242
Human 234 CAYNLVNSPHLKPAWVLDRALWRFSCDVAEGKYKEKGIPALIENDHHMNSIRKIIWEDIFPKLKL 298
..||.:.:|||..|..||:.|..||.:: |..|.|..::|...:..|...|...:...|||
Yeast 243 AGYNHITAPHLISAIELDQELLNFSRNL-----KSWGYPTELKNIEDLFKIMDGIKVHVLGSLKL 302
Human 299 WEFFQVDVNKAVEQFRRLLTQ---------ENRRVTKSDPNQHLTIIQD----PEYRRFGCTVDM 350
||::.|:|..|:...:..... ||.:...||..:..:.::| |.:...|.....
Yeast 303 WEYYAVNVQTALRDIKAHWNDESNESYSFPENIKDISSDFVKLASFVKDNVTEPNFGTLGERNSN 367
Human 351 NIALTTFIP-----HDKGPAAIEECCNWFHKRMEELNSEKHRLINYHQEQAVNCLLGNVFYERLA 410
.|.:..||. :|.|....|.........:.|:|...:|..:....:.:..|...:.|.||.
Yeast 368 RINVPKFIQLLKLINDGGSDDSESSLATAQNILNEVNLPLYREYDDDVSEILEQLFNRIKYLRLD 432
Human 411 GHGPKLGPVTRKHPLVTRYFTFPFEEIDFSMEESMIHLPNKACFLMAHNGWVMGDDPLRNFAEPG 475
..|||.||||...||...||| .|:..| ...:.:|:|||:...:||.:||...
Yeast 433 DGGPKQGPVTVDVPLTEPYFT-RFKGKD------------GTDYALANNGWIWNGNPLVDFASQN 484
Human 476 SEVYLRRELICWGDSVKLRYGNKPEDCPYLWAHMKKYTEITATYFQGVRLDNCHSTPLHVAEYML 540
|..|||||:|.|||.||||||..|||.||||..|.||.|:.|..|.|.|:|||||||:||.||.|
Yeast 485 SRAYLRREVIVWGDCVKLRYGKSPEDSPYLWERMSKYIEMNAKIFDGFRIDNCHSTPIHVGEYFL 549
Human 541 DAARNLQPNLYVVAELFTGSEDLDNVFVTRLGISSLIREAMSAYNSHEEGRLVYRYGGEPVGS-- 603
|.||...||||||||||:|||.||.:||.||||||||||||.|::..|..|||:::||.|:||
Yeast 550 DLARKYNPNLYVVAELFSGSETLDCLFVERLGISSLIREAMQAWSEEELSRLVHKHGGRPIGSYK 614
Human 604 ------FVQP--------------------CLRPLM-PAI-----AHALFMDITHDNECPIVHRS 636
|..| |:..:| |.| .||||||.|||||.|...|:
Yeast 615 FVPMDDFSYPADINLNEEHCFNDSNDNSIRCVSEIMIPKILTATPPHALFMDCTHDNETPFEKRT 679
Human 637 AYDALPSTTIVSMACCASGSTRGYDELVPHQISVVSEERFYTKWNPEALPSNTGEVNFQSGIIAA 701
..|.||:..:|::...|.||..||||:.||.:::|:|:|.|....|...|| .||...
Yeast 680 VEDTLPNAALVALCSSAIGSVYGYDEIFPHLLNLVTEKRHYDISTPTGSPS--------IGITKV 736
Human 702 RCAISKLHQELGAKGFIQVYVDQVDEDIVAVTRHSPSI--HQSVVAVSRTAFRNPKTSFYSKEVP 764
:..::.:...:|.|.: .:::..:.|......| |:..|...:..:...:..|...:.|
Yeast 737 KATLNSIRTSIGEKAY------DIEDSEMHVHHQGQYITFHRMDVKSGKGWYLIARMKFSDNDDP 795
Human 765 QMCIPGKIEEVVLEART--------IERNTKPYRKDENSINGTPDITVEIRE-HIQLNESKIVKQ 820
...:| .|||...| :||.......|:..|.|.|....|:.. .|..::||.:.
Yeast 796 NETLP----PVVLNQSTCSLRFSYALERVGDEIPNDDKFIKGIPTKLKELEGFDISYDDSKKIS- 855
Human 821 AGVATKGPNEYIQEIEFENLSPGSVIIFRVSLDPHAQVAVGILRNHLTQFSPHF-KSGSLAVDNA 884
..|.|||:.| ||:.||... :|.:.:...|| :||:|
Yeast 856 ---TIKLPNEFPQ---------GSIAIFETQ------------QNGVDESLDHFIRSGAL----- 891
Human 885 DPILKIPFASLASRLTLAELNQILYRCESEEKE---DGGGCYDIPNWSALKYAGLQGLMSVLAEI 946
...|.|||..:|.:|||.|.||.: ..||.|.|||:....|.||||.:|||.:|
Yeast 892 ---------KATSSLTLESINSVLYRSEPEEYDVSAGEGGAYIIPNFGKPVYCGLQGWVSVLRKI 947
Human 947 RPKNDLGHPFCNNLRSGDWMIDYVSNRL--ISRSGTIAEVGKWLQAMFFYLKQIPRYLIPCYFDA 1009
...|||.||...|||:|.|.:||..:|| .|....|.||..||::.|..:|::|.||:|.|| |
Yeast 948 VFYNDLAHPLSANLRNGHWALDYTISRLNYYSDEAGINEVQNWLRSRFDRVKKLPSYLVPSYF-A 1011
Human 1010 ILIG-AYTTLLDTAWKQMSSFVQNGSTFVKHLSLGSVQLCGVGKFPSLPILSPALMDVPYRLNEI 1073
::|| .|......|.:.||..:...:.||:.||:.|:|: |.:..|..||... :||
Yeast 1012 LIIGILYGCCRLKAIQLMSRNIGKSTLFVQSLSMTSIQM--VSRMKSTSILPGE--NVP------ 1066
Human 1074 TKEKEQCCVSLAAGLPHFSSGIFRCWGRDTFIALRGILLITGRYVEARNIILAFAGTLRHGLIPN 1138
|:||||||||....||||||.||:|||:||.|||:.||:..|||||.||:||||||
Yeast 1067 ---------SMAAGLPHFSVNYMRCWGRDVFISLRGMLLTTGRFDEAKAHILAFAKTLKHGLIPN 1122
Human 1139 LLGEGIYARYNCRDAVWWWLQCIQDYCKMVPNGLDILKCPVSRMYPTDDSAPLPAGTLDQP---- 1199
||..|...|||.|||.|::||.:|||..:||:|..||:..|:|.:|.||:. :| :|.|
Yeast 1123 LLDAGRNPRYNARDAAWFFLQAVQDYVYIVPDGEKILQEQVTRRFPLDDTY-IP---VDDPRAFS 1183
Human 1200 ----LFEVIQEAMQKHMQGIQFRERNAGPQIDRNMKDEGFNITAGVDEETGFVYGGNRFNCGTWM 1260
|.|:|.|.:.:|.:||:|||.||||.:||.|.|:|||:...||..||.::||:::||||||
Yeast 1184 YSSTLEEIIYEILSRHAKGIKFREANAGPNLDRVMTDKGFNVEIHVDWSTGLIHGGSQYNCGTWM 1248
Human 1261 DKMGESDRARNRGIPATPRDGSAVEIVGLSKSAVRWLLELSKKNIFPYHEVTVKRHGKAIKVSYD 1325
||||||::|.:.|||.|||||:|:||.||.|||:|:::||..|.:|.:.:|..:..| ::.:.
Yeast 1249 DKMGESEKAGSVGIPGTPRDGAAIEINGLLKSALRFVIELKNKGLFKFSDVETQDGG---RIDFT 1310
Human 1326 EWNRKIQDNFEKLFHVSEDPS-----DLNEKHPNLVHKRGIYKDSYGASSPWCDYQLRPNFTIAM 1385
|||:.:||||||.::|.|||| |::.|.. |::||||:|.|.:..|:.||||||||.|||
Yeast 1311 EWNQLLQDNFEKRYYVPEDPSQDADYDVSAKLG--VNRRGIYRDLYKSGKPYEDYQLRPNFAIAM 1373
Human 1386 VVAPELFTTEKAWKALEIAEKKLLGPLGMKTLDPDDMVYCGIYDNALDNDNYNLAKGFNYHQGPE 1450
.||||||..|.|.||:.||::.|.||:||:||||.|..|...|:|..|:|::..:||.|||||||
Yeast 1374 TVAPELFVPEHAIKAITIADEVLRGPVGMRTLDPSDYNYRPYYNNGEDSDDFATSKGRNYHQGPE 1438
Human 1451 WLWPIGYFLRAKLYFSRLMGP--ETTAK---TIVLVKNV---LSRHYVHLERSPWKGLPELTNEN 1507
|:|..||||||..:|.....| :..|| :..|.:.: |..|...:..|.|.||.||||::
Yeast 1439 WVWLYGYFLRAFHHFHFKTSPRCQNAAKEKPSSYLYQQLYYRLKGHRKWIFESVWAGLTELTNKD 1503
Human 1508 AQYCPFSCETQAWSIATILETLYDL 1532
.:.|..|..|||||.|.:|:..|||
Yeast 1504 GEVCNDSSPTQAWSSACLLDLFYDL 1528
| 
