Protein Alignment gadr-2 and CG12084

DIOPT Version :9

• Sequence 1: NP_501674.1
• Gene: gadr-2 / 177782
• WormBaseID: WBGene00007887
• Length: 732
• Species: Caenorhabditis elegans
• Sequence 2: NP_612112.1
• Gene: CG12084 / 192509
• FlyBaseID: FBgn0043458
• Length: 793
• Species: Drosophila melanogaster
• Alignment Length: 689
• Identity: 144/689 - (20%)
• Similarity: 241/689 - (34%)
• Gaps: 220/689 - (31%)

 Worm    35 NKVFSRLLE----LNNGISENLLKLIDG--KLNLSKINLQGVSVN---------RKIVNMVNKYC 84
            |::....||    .|..:.:::::|.:.  :.:|..:||:..:::         .|:..:...||
  Fly    54 NEICDGFLENYQRFNRPLDDSVIRLFEDTHRTSLKIVNLRNSTLSSIGLETLMRHKLFALSLWYC 118

 Worm    85 -----------------LESLILG-SSNL------NEGPSNDIFQAC-----VVDMASLLKNLLN 120
                             |.||.|| ||:|      ||....|....|     :|....::.:.|.
  Fly   119 DMISVGSHHLLAHYGDSLRSLELGISSHLLQYAEPNEKEPVDFQLTCPHLRRLVLNGVVMHHRLQ 183

 Worm   121 EGSLLNLRHLSIRTNQKFLSEWTQEISCLLPNLQSLSIKNRQFFCDESFSEHCQNFSNLLFLDIS 185
            ...|.:|.||.:  ....|:.::.|....||||.:|.:.|.....::..:..|  ...|..||||
  Fly   184 FAHLHDLGHLDL--TSCVLANFSLEALGSLPNLHTLILFNVWPIANQLHAICC--LRRLCTLDIS 244

 Worm   186 GTNLENLWGISHLNHLQVLHMRNLKFENNNCLMELFNLKDLRVLDISRDWDILNTQII------- 243
            .::..|..|...|.. |.|.|          ||:  ||:.|..||||      .|.:.
  Fly   245 ISSSGNGHGTYDLPD-QTLEM----------LMD--NLRHLTHLDIS------GTNLAGNGVATK 290

 Worm   244 EQYLECGM-VLPKLK----FLDCSG----TDICQYFLDNLLNT-------HD----------NLK 282
            |.....|| ..||::    ..|..|    |.....|| .|.:|       ||          |.:
  Fly   291 ESTTTSGMQQSPKMEQHFALTDIPGLASRTQRPLQFL-GLYHTAHWACKRHDIPALEVAGDANEQ 354

 Worm   283 QIVTWNTHLEDAVKAGIELLNGSTITTTINSLVHYMNLKRKAPIGWCLEVISNFLEIN---ENEQ 344
            ||:|...:..|         ....:|..:|.|.|....:....|...|:|:.:.::.:   ::.|
  Fly   355 QILTAARYYHD---------RPVLLTRVLNDLYHLFRFENCKDIHTALDVVLSAMDRHLKFKHMQ 410

 Worm   345 FNVSECI-----------------NHISRAM--GIEKSLES---RHNGIKCLTQISLHHYKKLRS 387
            .:.|..:                 |||.|.:  |:|..:..   ..||...|||.   |......
  Fly   411 ISGSATLFYIVKGRDRSKFGALLRNHIIRTLLNGMEMHITDDTMLRNGYLTLTQF---HMPVDVL 472

 Worm   388 FEIFRLLDYLLNYCNELQHYSPEINEHFWTSI-INLISLGACQFDYDKICLTVLKYLTKSKHFHG 451
            ||..||:..||:..::.:      .|.|...| |.|::..|||.|            .:.|.|.|
  Fly   473 FEYERLIKILLHGVSKTE------QEGFVQRIAIYLLNTLACQVD------------GRQKLFLG 519

 Worm   452 SITSTCSILTVLIPAMSR-----------KSMISITNEKENSTQIVEILKLGLDLKCAPWCISAL 505
            .:....::.|::...::|           .:|.::|:|
  Fly   520 ELGVVSTMFTLIKDRLTRSVFDDVMEVAWSTMWNVTDE--------------------------- 557

 Worm   506 GVLQLFSLINHDACRNIISVGGIDILFKCLKLAVKDIQTLAIN---VLTNIAIL------LKYDE 561
                  :.||   |:..:...|::...|||. ...|...|..|   :|.|:|.:      |...|
  Fly   558 ------TAIN---CKRFLDGRGMEYFLKCLH-TFPDRDELLRNMMGLLGNVAEVKWLRPKLMTQE 612

 Worm   562 IREIFTDENSRTIKQMLNKFDVSRSMHVISLLTLILSRE 600
            ..|:|    :|.:..:.:..:|..:.  .|::..:..||
  Fly   613 FIEVF----ARLLDSLSDGIEVGGAS--ASVVARVRERE 645

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gadr-2	NP_501674.1	None
CG12084	NP_612112.1	leucine-rich repeat	110..135	CDD:275381	2/24 (8%)
		leucine-rich repeat	136..167	CDD:275381	12/30 (40%)
		leucine-rich repeat	168..189	CDD:275381	3/20 (15%)
		leucine-rich repeat	190..213	CDD:275381	6/24 (25%)
		ARM	535..628	CDD:237987	22/133 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3665
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810