DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mtf1 and CG1792

DIOPT Version :9

Sequence 1:	NP_032662.3	Gene:	Mtf1 / 17764	MGIID:	101786	Length:	675	Species:	Mus musculus
Sequence 2:	NP_651878.1	Gene:	CG1792 / 43727	FlyBaseID:	FBgn0039860	Length:	372	Species:	Drosophila melanogaster

Alignment Length:	269	Identity:	80/269 - (29%)
Similarity:	119/269 - (44%)	Gaps:	41/269 - (15%)

- Green bases have known domain annotations that are detailed below.

Mouse    79 EGFLIDQEAMSQGYVQHIISPDQIHLTINPGSTPMPRNIEGATLTLQSECPETK----RKEVKRY 139
            |.|.:..|...| |.:.:...:.|.|.  |....:....|...:..|:|.|:.|    .|:::|.
  Fly    91 ESFAVGVEKEIQ-YAEEVTEIEVIDLL--PEEHLLEETEEPYEICEQNEQPQVKVPAQEKKLRRS 152

Mouse   140 QCTFEGCPRTYST---AGNLRTHQ--------------KTHRGEYTFVCNQEGCGKAFLTSYSLR 187
            ..|   .|..:::   |.|.:..:              |..|.:...:|.|  ||:.|....:.:
  Fly   153 TKT---TPTVFTSVKFADNSQATRTQWSRLTEDEVVALKRERRKRDCICEQ--CGRHFTCPSNFK 212

Mouse   188 IHVRVHTKEKPFECDVQGCEKAFNTLYRLKAHQRLHTGKT-FNCESQGCSKYFTTLSDLRKHIR- 250
            :|:..||..|.|.||  .|.:.|.|...|:.||.||.|.. |.|  :.|...::..|...:|.|
  Fly   213 LHLLRHTGVKSFACD--QCSQQFYTATLLRRHQELHAGNALFQC--RYCEATYSNASGRIQHERM 273

Mouse   251 THTGEKPFRCDHDGCGKAFAASHHLKTHVRTHTGERPFFCPSNGCEKTFSTQYSLKSH--MKGHD 313
            .||..|||.|..  |.|:||.|..|:||:.:|||.|.|.|.|  |:.:|..:..|.||  .|||.
  Fly   274 RHTNVKPFTCKE--CNKSFAMSGKLRTHMLSHTGVRAFHCDS--CQVSFVRRSHLTSHYRSKGHA 334

Mouse   314 NKGTAYSAL 322
            :..:|.:||
  Fly   335 HTSSAQAAL 343

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mtf1	NP_032662.3	COG5048	<92..308	CDD:227381	68/238 (29%)
		Nuclear localization signal. /evidence=ECO:0000255	132..137		2/8 (25%)
		C2H2 Zn finger	141..163	CDD:275368	5/38 (13%)
		zf-H2C2_2	155..182	CDD:290200	8/40 (20%)
		C2H2 Zn finger	171..193	CDD:275368	6/21 (29%)
		zf-H2C2_2	185..212	CDD:290200	9/26 (35%)
		C2H2 Zn finger	201..223	CDD:275368	8/21 (38%)
		C2H2 Zn finger	235..252	CDD:275368	4/17 (24%)
		zf-H2C2_2	244..270	CDD:290200	10/26 (38%)
		C2H2 Zn finger	260..282	CDD:275368	9/21 (43%)
		zf-H2C2_2	274..301	CDD:290200	12/26 (46%)
		C2H2 Zn finger	290..312	CDD:275368	8/23 (35%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	427..464
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	645..675
CG1792	NP_651878.1	zf-AD	6..80	CDD:214871
		C2H2 Zn finger	198..218	CDD:275368	6/21 (29%)
		C2H2 Zn finger	226..243	CDD:275368	6/18 (33%)
		C2H2 Zn finger	254..275	CDD:275368	5/22 (23%)
		zf-C2H2	281..303	CDD:278523	10/23 (43%)
		C2H2 Zn finger	283..303	CDD:275368	9/21 (43%)
		zf-H2C2_2	296..320	CDD:290200	12/25 (48%)
		C2H2 Zn finger	311..329	CDD:275368	7/19 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000