Protein Alignment unc-82 and par-1

DIOPT Version :9

• Sequence 1: NP_001255294.1
• Gene: unc-82 / 177514
• WormBaseID: WBGene00006814
• Length: 1793
• Species: Caenorhabditis elegans
• Sequence 2: NP_995894.2
• Gene: par-1 / 2768852
• FlyBaseID: FBgn0260934
• Length: 1170
• Species: Drosophila melanogaster
• Alignment Length: 1400
• Identity: 333/1400 - (23%)
• Similarity: 507/1400 - (36%)
• Gaps: 400/1400 - (28%)

 Worm    55 AVPHAFSGS--SNGTNASRPPADPKQPQRSRAERLRHRISERRTNAYMIPP----SSTTGKDPAI 113
            :||.|....  ||||.::  .|.|..|..|            .|||  :||    ||||. ..|.
  Fly    11 SVPEALPADSVSNGTASN--VAAPAAPVSS------------ATNA--VPPLAAVSSTTA-TYAT 58

 Worm   114 DALMNKYLNKSKENLDEGRKSRESSRAQEL--------LARTNREMSPTIDSLMKRYGNNNSSA- 169
            :::.....:...:...:.::..:|:.|..:        :|.|| .|.|.:.|  .....:||:|
  Fly    59 NSISTSSHSVKDQQQQQQQQQHDSANANIVSLPPTTTPVANTN-TMMPIVTS--SNSATSNSTAA 120

 Worm   170 ---------------------HRIKDSTVSRRESMEIQDNENSRSLDNKSCREARLSGSDVRIKW 213
                                 ..:..|..:...|.:.....:....:|.:...||||.:
  Fly   121 TPTPASGAAATGGVGSVSQGPATVSASAANTNHSHQHSHQHHHHVANNMTTDGARLSSN------ 179

 Worm   214 EVTNTEVKPTSSVKRFSVIIDPTGGRMPVGNSGSRSGRLARISQSNIRPFGSNGGGATNSYGPGT 278
               |:.|..:|::.... ...|..|..|..|....|...|.  .|.|:...|:..|:.|.
  Fly   180 ---NSAVVASSAINHHH-HHTPGSGVAPTVNKNVLSTHSAH--PSAIKQRTSSAKGSPNM----- 233

 Worm   279 HPMSGAEPCSPTKKEKH--RFEITKKLGSGTYGKVSLAYDHKFDREVAVKLIKKSAIESKADLVR 341
             .|..:.|......|:|  ::::.|.:|.|.:.||.||......:|||:|:|.|:.: :...|.:
  Fly   234 -QMRSSAPMRWRATEEHIGKYKLIKTIGKGNFAKVKLAKHLPTGKEVAIKIIDKTQL-NPGSLQK 296

 Worm   342 IRREIRIMSALNHPNIIQIYEVFENKDKIILVMEYSSGGELYDYVSRCGSLPEAEARRIFRQITS 406
            :.||:|||..|:||||:::::|.|.:..:.|:|||:||||::||:...|.:.|.|||..||||.|
  Fly   297 LFREVRIMKMLDHPNIVKLFQVIETEKTLYLIMEYASGGEVFDYLVLHGRMKEKEARVKFRQIVS 361

 Worm   407 AVLYCHKHRVAHRDLKLENILLDQNNNAKIADFGLSNYFADKNLLTTFCGSPLYASPEIINGTPY 471
            ||.|||:.|:.|||||.||:|||...|.||||||.||.|...:.|.||||||.||:||:..|..|
  Fly   362 AVQYCHQKRIIHRDLKAENLLLDSELNIKIADFGFSNEFTPGSKLDTFCGSPPYAAPELFQGKKY 426

 Worm   472 KGPEVDCWSLGILLYTLVYGSMPFDGRDFNRMVRQIKRGAYFEPETPST-ASMLIRNMLRVNPER 535
            .|||||.||||::|||||.||:||||.....:..::.||.|..|...|| ...|:|..|.:||.:
  Fly   427 DGPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLRKFLVLNPAK 491

 Worm   536 RATIFDIASHWWLNL----EENMPVIQELPENQIIDHTPLTEREETMIVQDLADEQ--DVFMEFG 594
            ||::..|....|:|:    :|..|.|:  |:                  .||||.:  :..:..|
  Fly   492 RASLETIMGDKWMNMGFEEDELKPYIE--PK------------------ADLADPKRIEALVAMG 536

 Worm   595 HLSSETRRKIEDFR----------IRRKEAEEFNDNSPVKPPKARKTDELT-------------G 636
            :..||....:...|          :.||..:..:|.|       |....|:             |
  Fly   537 YNRSEIEASLSQVRYDDVFATYLLLGRKSTDPESDGS-------RSGSSLSLRNISGNDAGANAG 594

 Worm   637 KISKEQPEEMKSAEKSL--RGVKEEKEKPKVVDPNDPLERLRQIENRLGQ-NKKDKEAAKTSA-- 696
            ..|.:.|.. :...:|:  ...|..:.....|.|.:....:......:|. |..:...|..||
  Fly   595 SASVQSPTH-RGVHRSISASSTKPSRRASSGVGPTNAAATVAAATGAVGAVNPSNNYNAAGSAAD 658

 Worm   697 ---------RVETVKLKEVKKEKSPEQQPEDPKTARGTSK---PADSRAPSFVPVKDRPETSE-- 747
                     |..|:....: ||.:.....::.:.|..|.|   .||:...|  |.|.|..|..
  Fly   659 RASVGSNFKRQNTIDSATI-KENTARLAAQNQRPASATQKMLTTADTTLNS--PAKPRTATKYDP 720

 Worm   748 --------------PERPRTRPHLTASAYRIETDSLNMLMNQVLEQMEKGPVNLNIIARIKAHPL 798
                          |.|..|....|:|     |:..|::           |...|:..|::
  Fly   721 TNGNRTVSGTSGIIPRRSTTLYEKTSS-----TEKTNVI-----------PAETNLFDRLR---- 765

 Worm   799 YDTRPMVKELLESIIAAQPEPVQKQTSKVVEQQTFSRQNTLTRKKKEDPLEEEIPEVPS-----P 858
                     :..::.:::..|     ..|..:.||  .:..||.:....||.......|     |
  Fly   766 ---------MASAVKSSRHFP-----RNVPSRSTF--HSGQTRARNNTALEYSGTSGASGDSSHP 814

 Worm   859 SR---------KMKERPWHSVEVG------FDPDEEPEHDRMQESIASNATEVTVQDTSFEDDSS 908
            .|         :..:||..:.|..      |....:.....|.:.|.....||      .:.::.
  Fly   815 GRMSFFSKLSSRFSKRPTIADEAAKPRVLRFTWSMKTTSPLMPDQIMQKIREV------LDQNNC 873

 Worm   909 DEEERKKTP---VASTPKTPVLIVEKQE------SSTNAEDEESDEGDDYSDAEMEELADEVDKK 964
            |.|:|::..   |...|.|..|:..:.|      .|.|....:...|   :....:.:|..:
  Fly   874 DYEQRERFVLWCVHGDPNTDSLVQWEIEVCKLPRLSLNGVRFKRISG---TSIGFKNIASRI--- 932

 Worm   965 GPSDSKLAPVVENLEANP------PPDPSSSPQFLDAFDRGLIKRQSKGKYQHTLINNYGRGVST 1023
             ..|.||.....|.|.|.      |.||:      |.......:|.|.......      ..:|.
  Fly   933 -AFDLKLXLNQTNNEGNAAATASRPTDPT------DTMTTTNCRRPSNDSTSRL------SELSL 984

 Worm  1024 ECESPTQQRKFFGGPQPSAELSPFLFDKAKEILQTYPNNKLDARGIDVELRRKLRMEKVKADLLK 1088
            .|.|.|.|:    |.|                                  |||      |:.|..
  Fly   985 LCRSLTSQQ----GSQ----------------------------------RRK------KSRLST 1005

 Worm  1089 QPKDGDKPRNSYVGSVPPRSPPPIVVKSDGEELDDEEEEEEDEEEIEETDSEEGSD-----FENF 1148
            ...:..|..||.:.:....||     .|..|.:...||    .|::...|::.|..     |.:|
  Fly  1006 GGSEDQKKSNSLLSAFQMYSP-----FSSKENMQSSEE----VEDLHVIDTQPGHSVDVPLFADF 1061

 Worm  1149 KPKRPIIAAVRRDDGAVVPVIHQTTRPAVVSPNSQNPRYQVASPKTSTVIQATPEKVPVAGTSAK 1213
            .|..||:                           :.....|...|||..      ||...|:..|
  Fly  1062 SPINPIM---------------------------EEDAEGVEGGKTSEA------KVISGGSGQK 1093

 Worm  1214 YLVTVAELKLKPTDKKEEA-------QLKEQLKDSEINSERKVTKGAAPSTISQDSDGKDTFESA 1271
            .              |.:.       :||..:|.:.....||:|.|.     ..|:|.|..
  Fly  1094 V--------------KGDGGGGGGGNRLKRNIKHTGSLIVRKLTAGR-----HNDADKKGA---- 1135

 Worm  1272 SAYIRRKNRERRQRNRTIGTAEEALRALERPSVDP 1306
               ||:|::|::         |.|....|||:..|
  Fly  1136 ---IRKKDKEQQ---------EVADTDKERPTSKP 1158

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
unc-82	NP_001255294.1	STKc_NUAK	295..548	CDD:270975	120/255 (47%)
par-1	NP_995894.2	STKc_MARK	252..504	CDD:270974	119/252 (47%)
		S_TKc	253..504	CDD:214567	119/251 (47%)
		UBA_MARK_Par1	525..563	CDD:270522	5/37 (14%)
		MARK1-3_C	839..936	CDD:213381	17/109 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910